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References from Impact of methodological variability on the prognostic performance of circulating tumor DNA in colorectal cancer: A systematic review and meta-analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
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Blood CEA levels for detecting recurrent colorectal cancer
2015 · External reference
Significance of carcinoembryonic antigen detection in the early diagnosis of colorectal cancer: a systematic review and meta-analysis
10.4240/wjgs.v15.i12.2907 · 2023 · External reference
Limited detection of small (≤ 10 mm) colorectal liver metastasis at preoperative CT in patients undergoing liver resection
10.1371/journal.pone.0189797 · 2017 · External reference
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10.1186/s40364-021-00306-8 · 2021 · External reference
DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells
2001 · External reference
Tumor fraction correlates with detection of actionable variants across > 23,000 circulating tumor DNA samples
2022 · External reference
Circulating mutant DNA to assess tumor dynamics
10.1038/nm.1789 · 2008 · External reference
Circulating Tumor DNA in stage III colorectal cancer, beyond minimal residual disease detection, toward assessment of adjuvant therapy efficacy and clinical behavior of recurrences
10.1158/1078-0432.ccr-21-2404 · 2022 · External reference
Circulating tumour DNA in predicting and monitoring survival of patients with locally advanced rectal cancer undergoing multimodal treatment: long-term results from a prospective multicenter study
10.1016/j.ebiom.2024.105548 · 2025 · External reference
Circulating tumor DNA analysis guiding adjuvant therapy in stage II Colon cancer
10.1056/nejmoa2200075 · 2022 · External reference
Circulating tumor DNA-guided adjuvant therapy in locally advanced colon cancer: the randomized phase 2/3 DYNAMIC-III trial
10.1038/s41591-025-04030-w · 2025 · External reference
ctDNA-based molecular residual disease and survival in resectable colorectal cancer
10.1038/s41591-024-03254-6 · 2024 · External reference
Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study
10.1186/s12885-020-07252-y · 2020 · External reference
From early detection to advanced therapies: how circulating tumor DNA is transforming the care of colorectal cancer
10.1007/s11912-025-01725-8 · 2025 · External reference
Circulating tumor DNA as prognostic marker in patients with metastatic colorectal cancer undergoing systemic therapy: a systematic review and meta-analysis
10.1016/j.ctrv.2025.102999 · 2025 · External reference
Circulating tumor DNA as a biomarker of prognosis prediction in colorectal cancer: a systematic review and meta-analysis
2025 · External reference
International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors
10.1016/j.jlb.2025.100301 · 2025 · External reference
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2021 · External reference
Circulating tumor cells and circulating tumor DNA detection in potentially resectable metastatic colorectal cancer: a prospective ancillary study to the unicancer Prodige-14 trial
10.3390/cells8060516 · 2019 · External reference
Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases
10.1016/j.ebiom.2021.103498 · 2021 · External reference
Circulating tumor DNA as a marker of minimal residual disease following local treatment of metastases from colorectal cancer
10.1080/0284186x.2020.1806357 · 2020 · External reference
Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer
10.1186/s13045-021-01089-z · 2021 · External reference
Preoperative liquid biopsy for optimal patient selection in metastatic colorectal cancer
10.1016/j.surg.2024.06.060 · 2025 · External reference
Development and validation of postoperative circulating tumor DNA combined with clinicopathological risk factors for recurrence prediction in patients with stage I-III colorectal cancer
10.1186/s12967-023-03884-3 · 2023 · External reference
Postoperative circulating tumor DNA detection is associated with the risk of recurrence in patients resected for a stage II colorectal cancer
10.3389/fonc.2022.973167 · 2022 · External reference
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
10.1002/ijc.33672 · 2021 · External reference
Unraveling the potential clinical utility of circulating tumor DNA detection in colorectal cancer-evaluation in a nationwide Danish cohort
10.1016/j.annonc.2023.11.009 · 2024 · External reference
Circulating tumor DNA detection after neoadjuvant treatment and surgery predicts recurrence in patients with early-stage and locally advanced rectal cancer
10.1016/j.ejso.2023.01.026 · 2023 · External reference
Postoperative circulating tumor DNA testing based on tumor naïve strategy after liver metastasis surgery in colorectal cancer patients
2023 · External reference
Feasibility of ctDNA in detecting minimal residual disease and predicting recurrence for colorectal cancer liver metastases
10.3389/fonc.2024.1418696 · 2024 · External reference
Impact of minimal residual disease on early recurrence of liver metastatic colorectal cancer
10.1111/cas.16442 · 2025 · External reference
MRI tumor regression grade and circulating tumor DNA as complementary tools to assess response and guide therapy adaptation in rectal cancer
10.1158/1078-0432.ccr-19-1996 · 2020 · External reference
Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer
10.1038/s41591-022-02115-4 · 2023 · External reference
Comprehensive genomic profiling (CGP)-informed personalized molecular residual disease (MRD) detection: an exploratory analysis from the PREDATOR study of metastatic colorectal cancer (mCRC) patients undergoing surgical resection
10.3390/ijms231911529 · 2022 · External reference
Detection of molecular residual disease using personalized circulating tumor DNA assay in patients with colorectal cancer undergoing resection of metastases
2021 · External reference
Serial circulating tumor DNA mutational status in patients with KRAS-mutant metastatic colorectal cancer from the phase 3 AIO KRK0207 trial
10.1093/clinchem/hvaa223 · 2020 · External reference
The added value of baseline circulating tumor DNA profiling in patients with molecularly hyperselected, left-sided metastatic colorectal cancer
10.1158/1078-0432.ccr-20-4699 · 2021 · External reference
Circulating tumor DNA as a marker of minimal residual disease after radical resection of colorectal liver metastases
2022 · External reference
Prognostic role of postoperative persistence of ctDNA molecular signature after liver resection for colorectal liver metastases: preliminary results from a prospective study
10.1016/j.ejso.2025.109706 · 2025 · External reference
Circulating tumor DNA predicts early recurrence following locoregional therapy for oligometastatic colorectal cancer
2024 · External reference
Minimal residual disease using a plasma-only circulating tumor DNA assay to predict recurrence of metastatic colorectal cancer following curative intent treatment
10.1158/1078-0432.ccr-23-3660 · 2024 · External reference
ctDNA MRD detection and personalized oncogenomic analysis in oligometastatic colorectal cancer from plasma and urine
2021 · External reference
The prognostic utility of KRAS mutations in tissue and circulating tumour DNA in colorectal cancer patients
10.3390/gastroent15010008 · 2024 · External reference
Circulating tumor DNA for prognosis assessment and postoperative management after curative-intent resection of colorectal liver metastases
10.1002/ijc.33924 · 2022 · External reference
Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer
10.1038/s41416-023-02300-3 · 2023 · External reference
Clinical utility of KRAS status in circulating plasma DNA compared to archival tumour tissue from patients with metastatic colorectal cancer treated with anti-epidermal growth factor receptor therapy
10.1016/j.ejca.2015.06.118 · 2015 · External reference
RAS mutations in circulating tumor DNA and clinical outcomes of rechallenge treatment with Anti-EGFR antibodies in patients with metastatic colorectal cancer
10.1200/po.20.00109 · 2020 · External reference
Detection of postoperative plasma circulating tumour DNA and lack of CDX2 expression as markers of recurrence in patients with localised colon cancer
10.1136/esmoopen-2020-000847 · 2020 · External reference
Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: individual patient pooled analysis of three cohort studies
10.1002/ijc.33312 · 2021 · External reference
Circulating tumor DNA analyses as markers of recurrence risk and benefit of adjuvant therapy for stage III Colon cancer
10.1001/jamaoncol.2019.3616 · 2019 · External reference
Circulating tumour cells & circulating tumour DNA in patients with resectable colorectal liver metastases (MIRACLE): a prospective, observational biomarker study
10.1016/j.eclinm.2025.103406 · 2025 · External reference
Evaluation of molecular residual disease by a fixed panel in resectable colorectal cancer
10.4143/crt.2023.1371 · 2024 · External reference
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10.1016/j.ejca.2008.10.026 · 2009 · External reference
Post-treatment surveillance in colorectal cancer
10.2478/v10019-010-0018-8 · 2010 · External reference
Prognostic value of the postoperative carcinoembryonic antigen level in colorectal cancer: a meta-analysis
10.1002/wjs.12349 · 2024 · External reference
Carcinoembryonic Antigen
2025 · External reference
Evaluation of recurrence risk after curative resection for patients with stage I to III colorectal cancer using the hazard function: retrospective analysis of a single-institution large cohort
10.1097/sla.0000000000004058 · 2022 · External reference
Incidence of recurrence and time to recurrence in stage I to III colorectal cancer: a nationwide Danish cohort study
10.1001/jamaoncol.2023.5098 · 2024 · External reference
Circulating tumor DNA as a prognostic indicator of colorectal cancer recurrence-a systematic review and meta-analysis
10.1007/s00384-022-04144-4 · 2022 · External reference
The effect of surgical trauma on circulating free DNA levels in cancer patients-implications for studies of circulating tumor DNA
10.1002/1878-0261.12729 · 2020 · External reference
Effects of collection and processing procedures on plasma circulating cell-free DNA from cancer patients
10.1016/j.jmoldx.2018.07.005 · 2018 · External reference
Performance of streck cfDNA blood collection tubes for liquid biopsy testing
10.1371/journal.pone.0166354 · 2016 · External reference
Clinical practice guideline for blood-based circulating tumor DNA assays
10.3343/alm.2023.0389 · 2024 · External reference
Comprehensive evaluation of methods to isolate, quantify, and characterize circulating cell-free DNA from small volumes of plasma
10.1007/s00216-015-8846-4 · 2015 · External reference
Extraction of cell-free DNA: evaluation of efficiency, quantity, and quality
10.1016/j.jmoldx.2024.01.008 · 2024 · External reference
Clinical performance of tumor-informed versus tumor-agnostic ctDNA assays for colorectal cancer recurrence: a systematic review and diagnostic accuracy meta-analysis
10.1016/j.ctrv.2025.103066 · 2026 · External reference