Research graph
References from Frailty-Related Metabolic Signature in the Association Between Frailty and Coronary Artery Disease: Modification by Genetic Susceptibility. Local targets link to admitted publications; unresolved targets remain external evidence.
Epidemiology and the magnitude of coronary artery disease and acute coronary syndrome: a narrative review
10.2991/jegh.k.201217.001 · 2021 · External reference
Cardiovascular disease and frailty: what are the mechanistic links?
10.1373/clinchem.2018.287318 · 2019 · External reference
Direct and Indirect effects of COVID-19 in frail elderly: interventions and recommendations
10.3390/jpm11100999 · 2021 · External reference
Metabolomics
10.1016/j.cmet.2007.10.005 · 2007 · External reference
Different plasma biomarker patterns associated with coronary atherosclerosis in low- versus high-risk individuals - an observational cross-sectional study
10.1016/j.atherosclerosis.2025.120457 · 2025 · External reference
New insights into healthy ageing, inflammageing and frailty using metabolomics
10.3389/fragi.2024.1426436 · 2024 · External reference
A large study of metabolomics reveals common and distinct metabolic biomarkers for type 2 diabetes, coronary heart disease, and stroke
10.1093/aje/kwae167 · 2025 · External reference
Intersecting genetics of frailty and cardiovascular disease
10.1007/s12603-021-1673-8 · 2021 · External reference
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
10.1371/journal.pmed.1001779 · 2015 · External reference
Frailty in older adults: evidence for a phenotype
10.1093/gerona/56.3.m146 · 2001 · External reference
Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank participants
10.1016/s2468-2667(18)30091-4 · 2018 · External reference
Associations between physical frailty and dementia incidence: a prospective study from UK Biobank
10.1016/s2666-7568(20)30007-6 · 2020 · External reference
Association of a healthy lifestyle, life’s essential 8 scores with incident macrovascular and microvascular disease among individuals with type 2 diabetes
10.1161/jaha.122.029441 · 2023 · External reference
UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits
2022 · External reference
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism
10.1039/b910205a · 2009 · External reference
Metabolomic network reveals novel biomarkers for type 2 diabetes mellitus in the UK Biobank study
10.1111/dom.16351 · 2025 · External reference
Associations of combined genetic and lifestyle risks with incident cardiovascular disease and diabetes in the UK biobank Study
10.1001/jamacardio.2018.1717 · 2018 · External reference
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
10.1016/s0140-6736(12)60240-2 · 2012 · External reference
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
10.1093/eurheartj/ehaa209 · 2020 · External reference
Metabolic signature of healthy lifestyle and risk of rheumatoid arthritis: observational and mendelian randomization study
10.1016/j.ajcnut.2023.04.034 · 2023 · External reference
Regularization and variable selection via the elastic net
10.1111/j.1467-9868.2005.00503.x · 2005 · External reference
Genomic selection using regularized linear regression models: ridge regression, lasso, elastic net and their extensions
10.1186/1753-6561-6-s2-s10 · 2012 · External reference
Metabolomic profiling identifies early biomarkers of frailty, balance impairment, and fall risks in older adults
2025 · External reference
Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses
10.1111/acel.13868 · 2023 · External reference
Serum albumin as a biomarker of (nutritional status in) sarcopenia
10.1007/s00774-024-01557-9 · 2025 · External reference
Biomarkers shared by frailty and sarcopenia in older adults: A systematic review and meta-analysis
10.1016/j.arr.2021.101530 · 2022 · External reference
Plasma amino acid signature for sarcopenic phenotypes in community-dwelling octogenarians: Results from the Kawasaki Aging Wellbeing Project
10.1016/j.exger.2023.112230 · 2023 · External reference
Serum creatinine and serum cystatin C as an index of muscle mass in adults
10.1097/mnh.0000000000001022 · 2024 · External reference
GlycA, a pro-inflammatory glycoprotein biomarker, and incident cardiovascular disease: relationship with C-reactive protein and renal function
10.1371/journal.pone.0139057 · 2015 · External reference
Metabolomic profiling identifies early biomarkers of frailty, balance impairment, and fall risks in older adults
10.1159/000546772 · 2025 · External reference
The intersection of frailty and metabolism
10.1016/j.cmet.2024.03.012 · 2024 · External reference
The association of prior intensive lifestyle intervention and diabetes support and education with frailty prevalence at long-term follow-up in the action for health in diabetes extension study
10.1093/gerona/glab312 · 2022 · External reference
Monounsaturated fatty acid levels may not affect cardiovascular events: results from a mendelian randomization analysis
10.3389/fnut.2020.00123 · 2020 · External reference
Fatty acids and frailty: a mendelian randomization study
10.3390/nu13103539 · 2021 · External reference
Relationship between serum fatty acids and components of physical frailty in community-dwelling Japanese older adults
10.14283/jfa.2020.67 · 2021 · External reference
Monounsaturated fatty acids in cardiovascular disease: intake, individual types, and content in adipose tissue as a biomarker of endogenous exposure
10.3390/nu17152509 · 2025 · External reference
Low levels of branched chain amino acids, eicosapentaenoic acid and micronutrients are associated with low muscle mass, strength and function in community-dwelling older adults
10.1007/s12603-018-1108-3 · 2019 · External reference
Duality of branched-chain amino acids in chronic cardiovascular disease: potential biomarkers versus active pathophysiological promoters
10.3390/nu16121972 · 2024 · External reference
Branched-chain amino acids in cardiovascular disease
10.1038/s41569-022-00760-3 · 2023 · External reference
Modification of coronary artery disease clinical risk factors by coronary artery disease polygenic risk score
10.1016/j.medj.2024.02.015 · 2024 · External reference
