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References from Chelidonic acid attenuates 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis by modulating oxidative stress and detoxification pathways in Golden Syrian hamsters. Local targets link to admitted publications; unresolved targets remain external evidence.
Oral squamous cell carcinomas: state of the field and emerging directions
10.1038/s41368-023-00249-w · 2023 · External reference
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2024 · External reference
Advancements and limitations in traditional anti-cancer therapies: a comprehensive review of surgery, chemotherapy, radiation therapy and hormonal therapy
10.1007/s12672-025-02198-8 · 2025 · External reference
The hamster buccal pouch model of oral carcinogenesis
10.1007/978-1-4939-3603-8_29 · 2016 · External reference
Of humans and hamsters: the hamster buccal pouch carcinogenesis model as a paradigm for oral oncogenesis and chemoprevention
10.2174/187152009789124619 · 2009 · External reference
Anticancer and antioxidant profiling effects of nerolidol against DMBA-induced oral experimental carcinogenesis
10.1002/jbt.23029 · 2022 · External reference
Oxidative stress and lipid peroxidation products in cancer progression and therapy
2012 · External reference
Lipid peroxidation: production, metabolism and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
10.1155/2014/360438 · 2014 · External reference
Antioxidants and reactive oxygen species: shaping human health and disease outcomes
10.3390/ijms26157520 · 2025 · External reference
Ursolic acid-loaded chitosan nanoparticles suppress 7,12-dimethylbenz(a)anthracene-induced oral tumor formation through their antilipid peroxidative potential in golden Syrian hamsters
10.1007/s00210-023-02509-2 · 2023 · External reference
Detoxification pathways in the liver
10.1007/bf01797915 · 1991 · External reference
Chemopreventive potential of esculetin in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis
10.1007/s11010-018-3321-0 · 2018 · External reference
Cytochrome P450 enzymes and drug metabolism in humans
10.3390/ijms222312808 · 2021 · External reference
The roles of cytochrome b5 in cytochrome P450 reactions
10.1002/jbt.10052 · 2002 · External reference
Glutathione S-transferases in cancer
10.3390/antiox10050701 · 2021 · External reference
Chemopreventive efficacy of Adhatoda vasica leaves in 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis
2015 · External reference
Cancer chemoprevention: signaling pathways and strategic approaches
10.1038/s41392-025-02167-1 · 2025 · External reference
Plant natural products: promising resources for cancer chemoprevention
10.3390/molecules26040933 · 2021 · External reference
Isolation and characterization of chelidonic acid from Sorghum vulgare
10.1016/s0031-9422(00)89991-4 · 1972 · External reference
Update: biological and chemical aspects of Senna spectabilis
2017 · External reference
Isolation and antiallergic activity of γ-pyrones from the flowers of Cassia spectabilis
1984 · External reference
Antimicrobial activities of Gloriosa superba Linn (Colchicaceae) extracts
10.1080/14756360701747409 · 2008 · External reference
Phytochemical and bioactive potential of Gloriosa superba L
2023 · External reference
A brief review on pharmacological efficacy of chelidonic acid
10.22270/jddt.v15i9.7352 · 2025 · External reference
Mitigation of cisplatin-induced nephrotoxicity by chelidonic acid in Wistar rats
10.1016/j.jtemb.2023.127321 · 2024 · External reference
Cardioprotective effect of chelidonic acid against doxorubicin-induced cardiac toxicity in rats
10.1016/j.repc.2024.06.003 · 2025 · External reference
Neuroprotective effect of chelidonic acid through oxidative stress reduction in paclitaxel-induced peripheral neuropathy in rats
10.1007/s00210-024-03550-5 · 2025 · External reference
Effects of acute and repeated dose toxicity profiling of chelidonic acid in rats: in silico and in vivo evidence
10.1002/cbdv.202301241 · 2023 · External reference
Chelidonic acid ameliorates atopic dermatitis symptoms through suppression of inflammatory mediators in vivo and in vitro
10.1186/s13765-022-00763-1 · 2023 · External reference
Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells
10.3109/08923973.2011.552508 · 2011 · External reference
Lipid peroxides and human diseases
10.1016/0009-3084(87)90071-5 · 1987 · External reference
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
10.1016/0003-2697(79)90738-3 · 1979 · External reference
A modified spectrophotometric assay of superoxide dismutase
1984 · External reference
Colorimetric assay of catalase
10.1016/0003-2697(72)90132-7 · 1972 · External reference
Vitamin E analysis methods for animal tissues
10.1016/s0076-6879(84)05019-9 · 1984 · External reference
Plasma levels of antioxidant beta-carotene and alpha-tocopherol in uterine cervix dysplasias and cancer
10.1080/01635589109514106 · 1991 · External reference
Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids
10.1016/0076-6879(79)62181-x · 1979 · External reference
The effect of sodium nitrite on red cell GSH
10.1007/bf02148042 · 1963 · External reference
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues
10.1016/0003-2697(69)90064-5 · 1969 · External reference
Selenium: biochemical role as a component of glutathione peroxidase
10.1126/science.179.4073.588 · 1973 · External reference
The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification and properties
10.1016/s0021-9258(20)82245-5 · 1964 · External reference
Glutathione S-transferases: the first enzymatic step in mercapturic acid formation
10.1016/s0021-9258(19)42083-8 · 1974 · External reference
Glutathione reductase
10.1016/s0076-6879(85)13062-4 · 1985 · External reference
DT-diaphorase
1967 · External reference
Investigating the effects of chelidonic acid on oxidative stress-induced premature cellular senescence in human skin fibroblast cells
2024 · External reference
Chemopreventive efficacy of geraniol against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis
10.1179/174329211x13020951739839 · 2011 · External reference
Anti-tumor initiating potential of andrographolide in 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis
10.7314/apjcp.2012.13.11.5701 · 2012 · External reference
Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification
10.1016/s0074-7696(06)60002-8 · 2007 · External reference
Potential chemopreventive effects of dietary combination of phytochemicals against cancer development
10.3390/ph16111591 · 2023 · External reference
Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: the antioxidant status and metabolizing enzymes expression in rats
10.1016/j.ecoenv.2019.01.004 · 2019 · External reference
Drug metabolism: phase I and phase II metabolic pathways
10.5772/intechopen.112854 · 2024 · External reference
Modulation of metabolic detoxification pathways using foods and food-derived components: a scientific review with clinical application
10.1155/2015/760689 · 2015 · External reference
Polyunsaturated fatty acids drive lipid peroxidation during ferroptosis
10.3390/cells12050804 · 2023 · External reference
Assessment of lipid peroxidation and antioxidant status in vanillic acid-treated 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis
2017 · External reference
Effects of acute and repeated dose toxicity profiling of chelidonic acid in rats: in silico and in vivo evidence
10.1002/cbdv.202301241 · ExternalCitation · doi-reference
The roles of cytochrome b5 in cytochrome P450 reactions
10.1002/jbt.10052 · ExternalCitation · doi-reference
Anticancer and antioxidant profiling effects of nerolidol against DMBA-induced oral experimental carcinogenesis
10.1002/jbt.23029 · ExternalCitation · doi-reference
The hamster buccal pouch model of oral carcinogenesis
10.1007/978-1-4939-3603-8_29 · ExternalCitation · doi-reference
Detoxification pathways in the liver
10.1007/bf01797915 · ExternalCitation · doi-reference
The effect of sodium nitrite on red cell GSH
10.1007/bf02148042 · ExternalCitation · doi-reference
Ursolic acid-loaded chitosan nanoparticles suppress 7,12-dimethylbenz(a)anthracene-induced oral tumor formation through their antilipid peroxidative potential in golden Syrian hamsters
10.1007/s00210-023-02509-2 · ExternalCitation · doi-reference
Neuroprotective effect of chelidonic acid through oxidative stress reduction in paclitaxel-induced peripheral neuropathy in rats
10.1007/s00210-024-03550-5 · ExternalCitation · doi-reference
Chemopreventive potential of esculetin in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis
10.1007/s11010-018-3321-0 · ExternalCitation · doi-reference
Advancements and limitations in traditional anti-cancer therapies: a comprehensive review of surgery, chemotherapy, radiation therapy and hormonal therapy
10.1007/s12672-025-02198-8 · ExternalCitation · doi-reference
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues
10.1016/0003-2697(69)90064-5 · ExternalCitation · doi-reference
Colorimetric assay of catalase
10.1016/0003-2697(72)90132-7 · ExternalCitation · doi-reference
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
10.1016/0003-2697(79)90738-3 · ExternalCitation · doi-reference
Lipid peroxides and human diseases
10.1016/0009-3084(87)90071-5 · ExternalCitation · doi-reference
Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids
10.1016/0076-6879(79)62181-x · ExternalCitation · doi-reference
Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: the antioxidant status and metabolizing enzymes expression in rats
10.1016/j.ecoenv.2019.01.004 · ExternalCitation · doi-reference
Mitigation of cisplatin-induced nephrotoxicity by chelidonic acid in Wistar rats
10.1016/j.jtemb.2023.127321 · ExternalCitation · doi-reference
Cardioprotective effect of chelidonic acid against doxorubicin-induced cardiac toxicity in rats
10.1016/j.repc.2024.06.003 · ExternalCitation · doi-reference
Glutathione S-transferases: the first enzymatic step in mercapturic acid formation
10.1016/s0021-9258(19)42083-8 · ExternalCitation · doi-reference
The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification and properties
10.1016/s0021-9258(20)82245-5 · ExternalCitation · doi-reference
Isolation and characterization of chelidonic acid from Sorghum vulgare
10.1016/s0031-9422(00)89991-4 · ExternalCitation · doi-reference
Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification
10.1016/s0074-7696(06)60002-8 · ExternalCitation · doi-reference
Vitamin E analysis methods for animal tissues
10.1016/s0076-6879(84)05019-9 · ExternalCitation · doi-reference
Glutathione reductase
10.1016/s0076-6879(85)13062-4 · ExternalCitation · doi-reference
Oral squamous cell carcinomas: state of the field and emerging directions
10.1038/s41368-023-00249-w · ExternalCitation · doi-reference
Cancer chemoprevention: signaling pathways and strategic approaches
10.1038/s41392-025-02167-1 · ExternalCitation · doi-reference
Plasma levels of antioxidant beta-carotene and alpha-tocopherol in uterine cervix dysplasias and cancer
10.1080/01635589109514106 · ExternalCitation · doi-reference
Antimicrobial activities of Gloriosa superba Linn (Colchicaceae) extracts
10.1080/14756360701747409 · ExternalCitation · doi-reference
Selenium: biochemical role as a component of glutathione peroxidase
10.1126/science.179.4073.588 · ExternalCitation · doi-reference
Lipid peroxidation: production, metabolism and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
10.1155/2014/360438 · ExternalCitation · doi-reference
Modulation of metabolic detoxification pathways using foods and food-derived components: a scientific review with clinical application
10.1155/2015/760689 · ExternalCitation · doi-reference
Chemopreventive efficacy of geraniol against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis
10.1179/174329211x13020951739839 · ExternalCitation · doi-reference
Chelidonic acid ameliorates atopic dermatitis symptoms through suppression of inflammatory mediators in vivo and in vitro
10.1186/s13765-022-00763-1 · ExternalCitation · doi-reference
Of humans and hamsters: the hamster buccal pouch carcinogenesis model as a paradigm for oral oncogenesis and chemoprevention
10.2174/187152009789124619 · ExternalCitation · doi-reference
A brief review on pharmacological efficacy of chelidonic acid
10.22270/jddt.v15i9.7352 · ExternalCitation · doi-reference
Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells
10.3109/08923973.2011.552508 · ExternalCitation · doi-reference
Glutathione S-transferases in cancer
10.3390/antiox10050701 · ExternalCitation · doi-reference
Polyunsaturated fatty acids drive lipid peroxidation during ferroptosis
10.3390/cells12050804 · ExternalCitation · doi-reference
Cytochrome P450 enzymes and drug metabolism in humans
10.3390/ijms222312808 · ExternalCitation · doi-reference
Antioxidants and reactive oxygen species: shaping human health and disease outcomes
10.3390/ijms26157520 · ExternalCitation · doi-reference
Plant natural products: promising resources for cancer chemoprevention
10.3390/molecules26040933 · ExternalCitation · doi-reference
Potential chemopreventive effects of dietary combination of phytochemicals against cancer development
10.3390/ph16111591 · ExternalCitation · doi-reference
Drug metabolism: phase I and phase II metabolic pathways
10.5772/intechopen.112854 · ExternalCitation · doi-reference
Anti-tumor initiating potential of andrographolide in 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis
10.7314/apjcp.2012.13.11.5701 · ExternalCitation · doi-reference
