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References from Chemical characterization of aconite polysaccharide and its ameliorative effect on ulcerative colitis by regulating gut microbiota and THDCA-driven TGR5/cAMP/PKA/NLRP3 pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Ulcerative colitis: clinical biomarkers, therapeutic targets, and emerging treatments
10.1016/j.tips.2024.08.003 · 2024 · External reference
Ulcerative colitis
10.1016/s0140-6736(23)00966-2 · 2023 · External reference
Ulcerative colitis
10.1016/s0140-6736(16)32126-2 · 2017 · External reference
Current treatment of ulcerative colitis
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Atractylodes macrocephala Koidz. volatile oil relieves acute ulcerative colitis via regulating gut microbiota and gut microbiota metabolism
10.3389/fimmu.2023.1127785 · 2023 · External reference
Polysaccharides from Aconitum carmichaelii leaves: structure, immunomodulatory and anti-inflammatory activities
10.1016/j.carbpol.2022.119655 · 2022 · External reference
Extraction, structural characterization, and immunoregulatory effect of a polysaccharide fraction from Radix Aconiti Lateralis Preparata (Fuzi)
10.1016/j.ijbiomac.2019.11.208 · 2020 · External reference
Fuzi lizhong pills alter microbial community compositions and metabolite profiles in ulcerative colitis rat with spleen-kidney yang deficiency syndrome
10.1016/j.jep.2024.118645 · 2024 · External reference
Polysaccharides from natural resources exhibit great potential in the treatment of ulcerative colitis: a review
10.1016/j.carbpol.2020.117189 · 2021 · External reference
Structural characterization and immunomodulatory activity of polysaccharides from the lateral roots of Aconitum carmichaelii
10.1016/j.ijbiomac.2024.136935 · 2024 · External reference
Repairing gut barrier by traditional Chinese medicine: roles of gut microbiota
10.3389/fcimb.2024.1389925 · 2024 · External reference
Interactions between gut microbiota and polyphenols: a mechanistic and metabolomic review
10.1016/j.phymed.2023.154979 · 2023 · External reference
Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment
10.1111/1751-2980.12849 · 2020 · External reference
Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine
10.1016/j.jpha.2021.10.003 · 2022 · External reference
Gut microbiota, bile acids, and nature compounds
10.1002/ptr.7517 · 2022 · External reference
Gastrodin ameliorates ulcerative colitis via modulating gut microbial tryptophan metabolism and AhR/NLRP3 pathway
10.1016/j.phymed.2025.157217 · 2025 · External reference
Dynamic variations in physicochemical characteristics of oolong tea polysaccharides during simulated digestion and fecal fermentation in vitro
10.1016/j.fochx.2022.100288 · 2022 · External reference
Interactions between polysaccharides and gut microbiota: a metabolomic and microbial review
10.1016/j.foodres.2022.111653 · 2022 · External reference
Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance
10.1016/j.lfs.2023.121501 · 2023 · External reference
Chemically induced mouse models of acute and chronic intestinal inflammation
10.1038/nprot.2017.044 · 2017 · External reference
Structural characterization and mechanisms of macrophage immunomodulatory activity of a pectic polysaccharide from Cucurbita moschata Duch
10.1016/j.carbpol.2021.118288 · 2021 · External reference
Structural characteristics and immunomodulatory effects of a long-chain polysaccharide from Laminaria japonica
10.3389/fnut.2022.762595 · 2022 · External reference
Characterisation, chain conformation and antifatigue effect of steamed ginseng polysaccharides with different molecular weight
10.3389/fphar.2021.712836 · 2021 · External reference
Isolation, structural characterization and cholesterol-lowering effects of a novel polysaccharide from mulberry (Morus alba L.) leaf
10.1016/j.indcrop.2023.117010 · 2023 · External reference
Structural mechanisms of NLRP3 inflammasome assembly and activation
10.1146/annurev-immunol-081022-021207 · 2023 · External reference
The NLRP3 inflammasome: contributions to inflammation-related diseases
10.1186/s11658-023-00462-9 · 2023 · External reference
Phytochemical inhibitors of the NLRP3 inflammasome for the treatment of inflammatory diseases
10.1016/j.phrs.2021.105710 · 2021 · External reference
Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats
10.1016/j.phymed.2024.155729 · 2024 · External reference
Chronic cold environment regulates rheumatoid arthritis through modulation of gut microbiota-derived bile acids
10.1016/j.scitotenv.2023.166837 · 2023 · External reference
Berberine regulates intestinal microbiome and metabolism homeostasis to treat ulcerative colitis
10.1016/j.lfs.2023.122385 · 2024 · External reference
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway
10.1038/s41467-024-45636-x · 2024 · External reference
Dietary Lactobacillus reuteri prevent from inflammation mediated apoptosis of liver via improving intestinal microbiota and bile acid metabolism
10.1016/j.foodchem.2022.134643 · 2023 · External reference
Live Lactobacillus acidophilus alleviates ulcerative colitis via the SCFAs/mitophagy/NLRP3 inflammasome axis
10.1039/d1fo03360c · 2022 · External reference
Ribonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
10.1038/s41467-024-50223-1 · 2024 · External reference
Herba Origani alleviated DSS-induced ulcerative colitis in mice through remolding gut microbiota to regulate bile acid and short-chain fatty acid metabolisms
10.1016/j.biopha.2023.114409 · 2023 · External reference
Enterohemorrhagic E. coli (EHEC) and the microbiome
10.1371/journal.ppat.1013224 · 2025 · External reference
Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia
10.1038/s41467-022-34687-7 · 2022 · External reference
Recent advances in modelling Shigella infection
10.1016/j.tim.2024.02.004 · 2024 · External reference
Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat
10.1002/hep.510270228 · 1998 · External reference
Astragalus polysaccharide attenuates nonalcoholic fatty liver disease through THDCA in high-fat diet-fed mice
10.1016/j.jep.2023.117401 · 2024 · External reference
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
10.1038/s41401-022-00880-z · 2022 · External reference
L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism
10.1002/jsfa.12222 · 2023 · External reference
Acanthopanax senticosus polysaccharide alleviates LPS-induced intestinal inflammation in piglets by gut microbiota and hyodeoxycholic acid regulation
10.1016/j.ijbiomac.2025.141467 · 2025 · External reference
Central anorexigenic actions of bile acids are mediated by TGR5
10.1038/s42255-021-00398-4 · 2021 · External reference
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
10.1038/s41401-023-01081-y · 2023 · External reference
The effect of in vitro digestion on the chemical and antioxidant properties of Lycium barbarum polysaccharides
10.1016/j.foodhyd.2023.108507 · 2023 · External reference
Biological factors controlling starch digestibility in human digestive system
10.1016/j.fshw.2022.07.037 · 2023 · External reference
Mechanisms of starch digestion by α-amylase-Structural basis for kinetic properties
10.1080/10408398.2014.922043 · 2017 · External reference
Investigation of the structural and immunomodulatory properties of alkali-soluble β-glucans from Pleurotus eryngii fruiting bodies
10.1016/j.carbpol.2023.121367 · 2023 · External reference
β-glucans from Agaricus bisporus mushroom products drive trained immunity
10.3389/fnut.2024.1346706 · 2024 · External reference
