Research graph
References from STING deficiency differentially affects skeletal muscle responses to high-intensity interval training and mechanical overload. Local targets link to admitted publications; unresolved targets remain external evidence.
Skeletal muscle: a brief review of structure and function
10.1007/s00223-014-9915-y · 2015 · External reference
Integrative biology of exercise
10.1016/j.cell.2014.10.029 · 2014 · External reference
Exercise metabolism and the molecular regulation of skeletal muscle adaptation
10.1016/j.cmet.2012.12.012 · 2013 · External reference
TLR4-mediated inflammatory responses regulate exercise-induced molecular adaptations in mouse skeletal muscle
10.3390/ijms23031877 · 2022 · External reference
Muscle damage and inflammation during recovery from exercise
10.1152/japplphysiol.00971.2016 · 2017 · External reference
Inflammation during skeletal muscle regeneration and tissue remodeling: application to exercise-induced muscle damage management
10.1038/icb.2015.97 · 2016 · External reference
Icing after eccentric contraction-induced muscle damage perturbs the disappearance of necrotic muscle fibers and phenotypic dynamics of macrophages in mice
10.1152/japplphysiol.01069.2020 · 2021 · External reference
Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
10.1016/j.cmet.2024.12.011 · 2025 · External reference
Regulation of muscle hypertrophy through granulin: relayed communication among mesenchymal progenitors, macrophages, and satellite cells
2024 · External reference
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
10.1038/s41467-018-03555-8 · 2018 · External reference
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity
10.1016/j.immuni.2015.01.012 · 2015 · External reference
Maintenance of skeletal muscle mitochondria in health, exercise, and aging
10.1146/annurev-physiol-020518-114310 · 2019 · External reference
Mitochondrial DNA stress primes the antiviral innate immune response
10.1038/nature14156 · 2015 · External reference
cGAS–STING drives ageing-related inflammation and neurodegeneration
10.1038/s41586-023-06373-1 · 2023 · External reference
STING activation promotes inflammatory response and delays skin wound healing in diabetic mice
10.1016/j.bbrc.2022.04.085 · 2022 · External reference
Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1
10.1128/jvi.00037-14 · 2014 · External reference
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
10.1126/science.1232458 · 2013 · External reference
CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
10.1016/j.celrep.2023.113626 · 2024 · External reference
High-intensity interval training ameliorates high-fat diet-induced metabolic disorders via the cyclic GMP-AMP synthase-stimulator of interferon gene signaling pathway
10.3390/ijms241813840 · 2023 · External reference
Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy
10.1002/jcla.24631 · 2022 · External reference
Exercise training ameliorates high-fat diet-induced skeletal muscle atrophy and ferroptosis via downregulation of STING
10.1016/j.freeradbiomed.2025.08.043 · 2025 · External reference
Effect of aging, endurance training, and denervation on innate immune signaling in skeletal muscle
10.1152/japplphysiol.00038.2025 · 2025 · External reference
STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation
10.1016/j.bbrc.2016.09.021 · 2016 · External reference
Rapamycin does not compromise exercise-induced muscular adaptations in female mice
10.1111/acel.70183 · 2025 · External reference
Markers of mitochondrial function and oxidative metabolism in skeletal muscle do not display intrinsic circadian regulation in female mice
10.1152/ajpendo.00027.2025 · 2025 · External reference
Design of amidobenzimidazole STING receptor agonists with systemic activity
10.1038/s41586-018-0705-y · 2018 · External reference
High intensity interval training improves physical performance and frailty in aged mice
10.1093/gerona/glx120 · 2018 · External reference
Synergist ablation as a rodent model to study satellite cell dynamics in adult skeletal muscle
10.1007/978-1-4939-3810-0_4 · 2016 · External reference
Direct and acute effects of advanced glycation end products on proteostasis in isolated mouse skeletal muscle
10.14814/phy2.16121 · 2024 · External reference
Comparisons of treatment means when factors do not interact in two-factorial studies
10.1007/s00726-011-0924-0 · 2012 · External reference
Two weeks of high-intensity interval training increases skeletal muscle mitochondrial respiration via complex-specific remodeling in sedentary humans
10.1152/japplphysiol.00467.2022 · 2023 · External reference
Physiological adaptations to low-volume, high-intensity interval training in health and disease
10.1113/jphysiol.2011.224725 · 2012 · External reference
Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle
10.14814/phy2.13893 · 2018 · External reference
Training intensity modulates changes in PGC-1α and p53 protein content and mitochondrial respiration, but not markers of mitochondrial content in human skeletal muscle
10.1096/fj.15-276907 · 2016 · External reference
A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics
10.1152/japplphysiol.00115.2015 · 2016 · External reference
4E-BP1, a multifactor regulated multifunctional protein
10.1080/15384101.2016.1151581 · 2016 · External reference
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
10.1073/pnas.0809136105 · 2008 · External reference
S6K1 Is required for increasing skeletal muscle force during hypertrophy
10.1016/j.celrep.2016.09.020 · 2016 · External reference
Effects of acute endurance exercise and exhaustive exercise on innate immune signals induced by mtDNA
10.1177/1721727x221134942 · 2022 · External reference
The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review
10.1186/s13102-022-00397-2 · 2022 · External reference
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
10.1126/science.aaa2630 · 2015 · External reference
Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice
10.1152/ajpcell.00201.2007 · 2007 · External reference
Reduced exercise endurance in interleukin-6-deficient mice
10.1210/en.2003-1319 · 2004 · External reference
Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise
10.1371/journal.pone.0156460 · 2016 · External reference
