Research graph
References from Leonurine alleviates radiation-induced brain injury by inhibiting ferroptosis-associated pathways and neuroinflammation. Local targets link to admitted publications; unresolved targets remain external evidence.
Cerebral radiation necrosis: Incidence, pathogenesis, diagnostic challenges, and future opportunities
10.1007/s11912-019-0818-y · 2019 · External reference
(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus
10.3389/fimmu.2022.977698 · 2022 · External reference
Molecular, cellular and functional effects of radiation-induced brain injury: A review
10.3390/ijms161126068 · 2015 · External reference
DEGRO practical guideline for central nervous system radiation necrosis part 1: Classification and a multistep approach for diagnosis
10.1007/s00066-022-01994-3 · 2022 · External reference
EANO–ESMO clinical practice guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours
10.1016/j.annonc.2021.07.016 · 2021 · External reference
Leonurine reduces oxidative stress and provides neuroprotection against ischemic injury via modulating oxidative and NO/NOS pathway
10.3390/ijms231710188 · 2022 · External reference
Ferroptosis: An iron-dependent form of nonapoptotic cell death
10.1016/j.cell.2012.03.042 · 2012 · External reference
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
10.1038/ncb3064 · 2014 · External reference
Radiation therapy for brain metastases: An ASTRO clinical practice guideline
10.1016/j.prro.2022.02.003 · 2022 · External reference
Endothelial response to blood-brain barrier disruption in the human brain
10.1172/jci.insight.187328 · 2024 · External reference
Ferroptosis in radiation-induced brain injury: Roles and clinical implications
10.1186/s12938-024-01288-y · 2024 · External reference
Ferroptosis in radiation-induced brain injury: Roles and clinical implications
10.1186/s12938-024-01288-y · 2024 · External reference
Radiation-induced brain injury: Mechanistic insights and the promise of gut–brain axis therapies
2024 · External reference
Active components of Ginkgo biloba flower attenuate radiation-induced cognitive impairment via inhibiting ferroptosis
2026 · External reference
Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy
10.1016/j.phymed.2016.10.005 · 2016 · External reference
Microglia as therapeutic target for radiation-induced brain injury
10.3390/ijms23158286 · 2022 · External reference
Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function
10.1161/strokeaha.110.589895 · 2010 · External reference
Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
10.1038/nrneurol.2016.185 · 2017 · External reference
Proton therapy - Present and future
10.1016/j.addr.2016.11.006 · 2017 · External reference
Blockade of Kv1.3 channels ameliorates radiation-induced brain injury
10.1093/neuonc/not221 · 2014 · External reference
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury
10.1016/j.freeradbiomed.2024.01.021 · 2024 · External reference
Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8(+) T lymphocytes
10.1016/j.neuron.2022.12.009 · 2023 · External reference
Leonurine exerts anti-inflammatory effect by regulating inflammatory signaling pathways and cytokines in LPS-induced mouse mastitis
10.1007/s10753-014-0009-9 · 2015 · External reference
A systematic review informing the management of symptomatic brain radiation necrosis after stereotactic radiosurgery and international stereotactic radiosurgery society recommendations
10.1016/j.ijrobp.2023.07.015 · 2024 · External reference
Skin wound following irradiation aggravates radiation-induced brain injury in a mouse model
10.3390/ijms241310701 · 2023 · External reference
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury
10.1186/s12974-022-02596-7 · 2022 · External reference
Discovery of Leonuri and therapeutical applications: From bench to bedside
10.1016/j.pharmthera.2018.01.006 · 2018 · External reference
DEGRO practical guideline for central nervous system radiation necrosis part 1: Classification and a multistep approach for diagnosis
10.1007/s00066-022-01994-3 · ExternalCitation · doi-reference
Leonurine exerts anti-inflammatory effect by regulating inflammatory signaling pathways and cytokines in LPS-induced mouse mastitis
10.1007/s10753-014-0009-9 · ExternalCitation · doi-reference
Cerebral radiation necrosis: Incidence, pathogenesis, diagnostic challenges, and future opportunities
10.1007/s11912-019-0818-y · ExternalCitation · doi-reference
Proton therapy - Present and future
10.1016/j.addr.2016.11.006 · ExternalCitation · doi-reference
EANO–ESMO clinical practice guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours
10.1016/j.annonc.2021.07.016 · ExternalCitation · doi-reference
Ferroptosis: An iron-dependent form of nonapoptotic cell death
10.1016/j.cell.2012.03.042 · ExternalCitation · doi-reference
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury
10.1016/j.freeradbiomed.2024.01.021 · ExternalCitation · doi-reference
A systematic review informing the management of symptomatic brain radiation necrosis after stereotactic radiosurgery and international stereotactic radiosurgery society recommendations
10.1016/j.ijrobp.2023.07.015 · ExternalCitation · doi-reference
Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8(+) T lymphocytes
10.1016/j.neuron.2022.12.009 · ExternalCitation · doi-reference
Discovery of Leonuri and therapeutical applications: From bench to bedside
10.1016/j.pharmthera.2018.01.006 · ExternalCitation · doi-reference
Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy
10.1016/j.phymed.2016.10.005 · ExternalCitation · doi-reference
Radiation therapy for brain metastases: An ASTRO clinical practice guideline
10.1016/j.prro.2022.02.003 · ExternalCitation · doi-reference
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
10.1038/ncb3064 · ExternalCitation · doi-reference
Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
10.1038/nrneurol.2016.185 · ExternalCitation · doi-reference
Blockade of Kv1.3 channels ameliorates radiation-induced brain injury
10.1093/neuonc/not221 · ExternalCitation · doi-reference
Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function
10.1161/strokeaha.110.589895 · ExternalCitation · doi-reference
Endothelial response to blood-brain barrier disruption in the human brain
10.1172/jci.insight.187328 · ExternalCitation · doi-reference
Ferroptosis in radiation-induced brain injury: Roles and clinical implications
10.1186/s12938-024-01288-y · ExternalCitation · doi-reference
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury
10.1186/s12974-022-02596-7 · ExternalCitation · doi-reference
(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus
10.3389/fimmu.2022.977698 · ExternalCitation · doi-reference
Molecular, cellular and functional effects of radiation-induced brain injury: A review
10.3390/ijms161126068 · ExternalCitation · doi-reference
Microglia as therapeutic target for radiation-induced brain injury
10.3390/ijms23158286 · ExternalCitation · doi-reference
Leonurine reduces oxidative stress and provides neuroprotection against ischemic injury via modulating oxidative and NO/NOS pathway
10.3390/ijms231710188 · ExternalCitation · doi-reference
Skin wound following irradiation aggravates radiation-induced brain injury in a mouse model
10.3390/ijms241310701 · ExternalCitation · doi-reference
