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References from Investigation of molecular effects of beta caryophyllene in cadmium-induced nephrotoxicity model in rats: in silico and in vivo studies. Local targets link to admitted publications; unresolved targets remain external evidence.
β-Caryophyllene attenuates cadmium induced neurotoxicity in rats by modulating different cellular signaling pathways
10.1016/j.neuro.2025.04.006 · 2025 · External reference
The European maximum level for cadmium in bovine kidneys is in Belgium only realistic for cattle up to 2 years of age
10.1080/02652030903081937 · 2009 · External reference
Syringic acid alleviates cadmium-induced neurotoxicity in rats by modulating cellular signaling pathways
10.1016/j.intimp.2025.114816 · 2025 · External reference
Investigation of neurotoxicity oxidative stress and oxidative DNA damage in cadmium-induced brain injury in rats
10.5152/vetscipract.2023.222441 · 2023 · External reference
Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: a mechanistic study
10.1016/j.lfs.2020.117324 · 2020 · External reference
Cadmium renal toxicity via apoptotic pathways
10.1248/bpb.b212014 · 2012 · External reference
The mechanism of the cadmium-induced toxicity and cellular response in the liver
10.1016/j.tox.2022.153339 · 2022 · External reference
Cadmium toxicity: effects on human reproduction and fertility
10.1515/reveh-2019-0016 · 2019 · External reference
Toxicodynamics of lead, cadmium, mercury and arsenic- induced kidney toxicity and treatment strategy: a mini review
10.1016/j.toxrep.2018.05.012 · 2018 · External reference
10.1007/978-94-007-5179-8_14
10.1007/978-94-007-5179-8_14 · External reference
Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2α
10.1016/j.biopha.2021.111862 · 2021 · External reference
Cadmium stress: an oxidative challenge
10.1007/s10534-010-9329-x · 2010 · External reference
Heavy metal poisoning: the effects of cadmium on the kidney
10.1007/s10534-010-9328-y · 2010 · External reference
β -caryophyllene and β -caryophyllene oxide—natural compounds of anticancer and analgesic properties
10.1002/cam4.816 · 2016 · External reference
β-Caryophyllene, the major constituent of copaiba oil, reduces systemic inflammation and oxidative stress in arthritic rats
10.1002/jcb.27369 · 2018 · External reference
The potential therapeutic role of beta-caryophyllene as a chemosensitizer and an inhibitor of angiogenesis in cancer
10.3390/molecules30081751 · 2025 · External reference
Antibacterial activity and mode of action of β-caryophyllene on Bacillus cereus
10.33073/pjm-2020-007 · 2020 · External reference
A systematic review on the neuroprotective perspectives of beta-caryophyllene
10.1002/ptr.6199 · 2018 · External reference
IUPHAR review- preclinical models of neuropathic pain: evaluating multifunctional properties of natural cannabinoid receptors ligands
10.1016/j.phrs.2023.107013 · 2024 · External reference
Protective effects of curcumin against valproic acid induced brain kidney and liver damage in rats
2024 · External reference
Investigation of the effects of pulmonary adenomatosis on oxidative dna damage, inflammation, apoptosis, and autophagy in lung tissues in sheep
10.1016/j.smallrumres.2023.107171 · 2024 · External reference
Cellular pathophysiology of Leptospira interrogans infection in canine testicular tissue: role of the TLR4/NF-kB/JNK pathway
10.1016/j.jcpa.2024.11.001 · 2025 · External reference
Differential TLR2 and TLR4 mediated inflammatory and apoptotic responses in asymptomatic and symptomatic Leptospira interrogans infections in canine uterine tissue
10.1016/j.micpath.2024.107186 · 2025 · External reference
Gallic acid’s protective mechanisms against acrylamide-induced pulmonary injury: in vivo and in silico insights into the Nrf-2/HO-1/NFκB pathway modulation
10.1007/s00210-025-03996-1 · 2025 · External reference
Cadmium, an environmental contaminant, exacerbates alzheimer’s pathology in the aged mice’s brain
10.3389/fnagi.2021.650930 · 2021 · External reference
Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney
10.3390/ijerph16020274 · 2019 · External reference
Cadmium (Cd) and chlorpyrifos (CPF) induced pulmonary toxicity in wistar rats
10.30954/2277-940x.03.2020.23 · 2020 · External reference
Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation
10.1016/j.lfs.2021.119610 · 2021 · External reference
β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner
10.1016/j.freeradbiomed.2012.01.014 · 2012 · External reference
β-Caryophyllene may attenuate hyperoxaluria-induced kidney dysfunction in rats by regulating stress marker KIM-1/MCP-1 and NF-κB signaling pathway
10.1002/jbt.22891 · 2021 · External reference
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view
10.1016/j.lfs.2022.120971 · 2022 · External reference
Thymoquinone ameliorates cadmium-induced nephrotoxicity, apoptosis, and oxidative stress in rats is based on its anti-apoptotic and anti-oxidant properties
10.1007/s12011-015-0453-x · 2016 · External reference
The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis
10.1152/physrev.00023.2017 · 2018 · External reference
Attenuation of inflammation, oxidative stress and TGF-β1/Smad3 signaling and upregulation of Nrf2/HO-1 signaling mediate the protective effect of diallyl disulfide against cadmium nephrotoxicity
10.1016/j.tice.2024.102576 · 2024 · External reference
Activation of toll-like receptors 2 and 4 in Aspergillus fumigatus keratitis
10.1177/1753425908101521 · 2009 · External reference
Selenium antagonizes cadmium-induced inflammation and oxidative stress via suppressing the interplay between NLRP3 inflammasome and HMGB1/NF-κB pathway in duck hepatocytes
10.3390/ijms23116252 · 2022 · External reference
Royal jelly attenuates cadmium-induced nephrotoxicity in male mice
10.1038/s41598-019-42368-7 · 2019 · External reference
Carnosic acid attenuates cadmium induced nephrotoxicity by inhibiting oxidative stress, promoting Nrf2/HO-1 signalling and impairing TGF-β1/smad/collagen IV signalling
10.3390/molecules24224176 · 2019 · External reference
Renoprotective and oxidative stress-modulating effects of taxifolin against cadmium-induced nephrotoxicity in mice
10.3390/life12081150 · 2022 · External reference
β-caryophyllene and docosahexaenoic acid, isolated or associated, have potential antinociceptive and anti-inflammatory effects in vitro and in vivo
10.1038/s41598-022-23842-1 · 2022 · External reference
The investigation of the effect of fraxin on hepatotoxicity induced by cisplatin in rats
2020 · External reference
Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats
10.1016/j.lfs.2016.01.038 · 2016 · External reference
Beneficial effects of chrysin on cadmium-induced nephrotoxicity in rats: modulating the levels of Nrf2/HO-1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling pathways
10.1016/j.gene.2023.147502 · 2023 · External reference
10.1007/978-981-13-8871-2_29
10.1007/978-981-13-8871-2_29 · External reference
Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis
10.1039/c9mt00227h · 2019 · External reference
Cadmium neurotoxicity and therapeutic strategies
10.1002/jbt.23670 · 2024 · External reference
Therapeutic potential of β-caryophyllene: a dietary cannabinoid in diabetes and associated complications
10.3390/nu12102963 · 2020 · External reference
Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis
10.1007/s11011-022-00945-2 · 2022 · External reference
Environment-relevant concentrations of cadmium induces necroptosis and inflammation; baicalein maintains gill homeostasis through suppressing ROS/ER stress signaling in common carps (Cyprinus carpio L.)
10.1016/j.envpol.2023.122805 · 2024 · External reference
Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes
10.1016/j.cbi.2023.110410 · 2023 · External reference
Cadmium disrupted ER Ca2+ homeostasis by inhibiting SERCA2 expression and activity to induce apoptosis in renal proximal tubular cells
10.3390/ijms24065979 · 2023 · External reference
Beta-caryophyllene is a dietary cannabinoid
10.1073/pnas.0803601105 · 2008 · External reference
