Research graph
References from Pre-hospital time and risk of perforation in patients with acute appendicitis in 112 countries (AlliGatOr): an international, prospective, observational cohort study. Local targets link to admitted publications; unresolved targets remain external evidence.
The global incidence of appendicitis: a systematic review of population-based studies
10.1097/sla.0000000000002188 · 2017 · External reference
Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries
10.1016/s0140-6736(22)01884-0 · 2022 · External reference
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
10.1016/s0140-6736(20)31182-x · 2020 · External reference
Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial
10.1016/s0140-6736(21)01548-8 · 2021 · External reference
The rate of negative appendicectomy and perforated appendicitis as quality indicators of the general surgical service in a district general hospital in Cavan, Republic of Ireland
2023 · External reference
Pediatric appendicitis rupture rate: a national indicator of disparities in healthcare access
10.1186/1478-7954-3-4 · 2005 · External reference
Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management
10.1016/s0140-6736(15)00275-5 · 2015 · External reference
Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
10.1186/s13017-018-0179-0 · 2018 · External reference
The effect of appendectomy in future tubal infertility and ectopic pregnancy: a systematic review and meta-analysis
10.1016/j.jss.2014.08.017 · 2014 · External reference
The impact of timing on outcomes in appendicectomy: a systematic review and network meta-analysis
10.1186/s13017-024-00549-4 · 2024 · External reference
Disconnect between incidence of nonperforated and perforated appendicitis: implications for pathophysiology and management
10.1097/01.sla.0000256391.05233.aa · 2007 · External reference
A randomized trial comparing antibiotics with appendectomy for appendicitis
10.1056/nejmoa2014320 · 2020 · External reference
A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis: results of the COMMA trial
10.1097/sla.0000000000004785 · 2021 · External reference
State of the art review: evidence based management of acute appendicitis
10.62463/surgery.45 · 2024 · External reference
Conservative versus surgical management of acute appendicitis: a systematic review
2024 · External reference
Antibiotic treatment for uncomplicated appendicitis really works: results from 5 years of observation in the APPAC trial
10.1001/jama.2018.13368 · 2018 · External reference
Clinical practice. Acute appendicitis—appendectomy or the “antibiotics first” strategy
10.1056/nejmcp1215006 · 2015 · External reference
Safety of short, in-hospital delays before surgery for acute appendicitis: multicentre cohort study, systematic review, and meta-analysis
10.1097/sla.0000000000000492 · 2014 · External reference
Appendicitis Global Outcomes (AlliGatOr) study protocol: identifying areas for whole systems strengthening in emergency care pathways
10.62463/surgery.204 · 2025 · External reference
The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies
10.1016/s0140-6736(07)61602-x · 2007 · External reference
The REDCap consortium: building an international community of software platform partners
10.1016/j.jbi.2019.103208 · 2019 · External reference
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
10.1016/s0140-6736(21)00001-5 · 2021 · External reference
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
10.1111/anae.15458 · 2021 · External reference
Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey
10.1097/01.sla.0000133083.54934.ae · 2004 · External reference
Access to and quality of elective care: a prospective cohort study using hernia surgery as a tracer condition in 83 countries
10.1016/s2214-109x(24)00142-6 · 2024 · External reference
Overestimation of risk ratios by odds ratios in trials and cohort studies: alternatives to logistic regression
10.1503/cmaj.101715 · 2012 · External reference
glmmTMB balances speed and flexibility among packages for zero-inflated generalized linear mixed modeling
10.32614/rj-2017-066 · 2017 · External reference
Usable and precise asymptotics for generalized linear mixed model analysis and design
10.1111/rssb.12473 · 2022 · External reference
Risk factors for perforated appendicitis in the acute care surgery era-minimizing the patient’s delayed presentation factor
10.1016/j.jss.2019.01.031 · 2019 · External reference
Trends in rates of perforated appendix, 2001–2010
2006 · External reference
Do racial/ethnic and economic factors affect the rate of complicated appendicitis in children?
2020 · External reference
Appendix perforation: contributing risk factors
10.18203/2349-2902.isj20251896 · 2025 · External reference
Costs associated with postoperative intra-abdominal abscess in pediatric perforated appendicitis: a retrospective cohort study
10.1016/j.surg.2022.01.042 · 2022 · External reference
The cost effectiveness of early management of acute appendicitis underlies the importance of curative surgical services to a primary healthcare programme
10.1308/003588413x13511609958415 · 2013 · External reference
Role of preoperative in-hospital delay on appendiceal perforation while awaiting appendicectomy (PERFECT): a Nordic, pragmatic, open-label, multicentre, non-inferiority, randomised controlled trial
10.1016/s0140-6736(23)01311-9 · 2023 · External reference
Meta-analysis of in-hospital delay before surgery as a risk factor for complications in patients with acute appendicitis
10.1002/bjs.10873 · 2018 · External reference
The Lancet Commission on diagnostics: transforming access to diagnostics
10.1016/s0140-6736(21)00673-5 · 2021 · External reference
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study
10.1007/s00464-018-6064-9 · 2018 · External reference
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
10.1002/bjs.11440 · 2020 · External reference
Multicentre observational study of performance variation in provision and outcome of emergency appendicectomy
10.1002/bjs.9201 · 2013 · External reference
An update to the negative appendectomy rate: review article
2025 · External reference
Imaging utilization affects negative appendectomy rates in appendicitis: An ACS-NSQIP study
10.1016/j.amjsurg.2018.12.072 · 2019 · External reference
