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References from Glucocorticoid-induced METTL3 promotes SONFH by enhancing MEG3 m6A methylation and subsequent ABL2 upregulation. Local targets link to admitted publications; unresolved targets remain external evidence.
Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)
10.1016/j.jot.2019.12.004 · 2020 · External reference
Capillary Force-Driven Capture of Magnetic Nanoparticles in Calcium Phosphate Hollow-Tube Whisker Scaffolds for Osteonecrosis of the Femoral Head
10.1021/acsnano.5c02874 · 2025 · External reference
Nationwide epidemiologic survey of idiopathic osteonecrosis of the femoral head
10.1007/s11999-010-1292-x · 2010 · External reference
Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head
10.3389/fmolb.2025.1578755 · 2025 · External reference
Operative Management of Avascular Necrosis of the Femoral Head in Skeletally Immature Patients: A Systematic Review
2022 · External reference
Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling
10.1186/s13287-023-03371-y · 2023 · External reference
TRF16 affects NFKBIA stability and promotes osteoarthritis progression by regulating ALKBH5 expression in m6A-dependent manner
10.1038/s42003-025-08299-y · 2025 · External reference
WTAP mediated m6A modification stabilizes PDIA3P1 and promotes tumor progression driven by histone lactylation in esophageal squamous cell carcinoma
10.1002/advs.202506529 · 2025 · External reference
Novel insights into the regulatory role of N6-methyladenosine in the pathogenesis and clinical treatment of osteoarthritis: research status and prospect
10.2147/jir.s508973 · 2025 · External reference
YTHDF2-mediated m6A methylation inhibition by miR27a as a protective mechanism against hormonal osteonecrosis in BMSCs
10.1186/s12891-024-07481-3 · 2024 · External reference
M6A methylation modification and immune infiltration analysis in osteonecrosis of the femoral head
10.1186/s13018-024-04590-6 · 2024 · External reference
LncRNA-MEG3 regulates muscle mass and metabolic homeostasis by facilitating SUZ12 liquid-liquid phase separation
2025 · External reference
Deciphering the mysteries of MEG3 LncRNA and its implications in genitourinary cancers
10.3389/fonc.2025.1519103 · 2025 · External reference
LncRNA MEG3 exacerbates diabetic cardiomyopathy via activating pyroptosis signaling pathway
10.3389/fphar.2025.1538059 · 2025 · External reference
LncRNA MEG3 promotes pyroptosis via miR-145-5p/TLR4/NLRP3 axis and aggravates cerebral ischemia-reperfusion injury
10.1007/s11011-025-01613-x · 2025 · External reference
Macrophage migration inhibitory factor protects bone marrow mesenchymal stem cells from hypoxia/ischemia-induced apoptosis by regulating lncRNA MEG3
10.1631/jzus.b2200110 · 2022 · External reference
GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor
10.1093/bioinformatics/btm254 · 2007 · External reference
Random Forests
10.1023/a:1010933404324 · 2001 · External reference
A combined deep learning framework for mammalian m6A site prediction
2024 · External reference
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data
10.1093/nar/gkt1248 · 2014 · External reference
miRDB: an online database for prediction of functional microRNA targets
10.1093/nar/gkz757 · 2020 · External reference
miRWalk: An online resource for prediction of microRNA binding sites
10.1371/journal.pone.0206239 · 2018 · External reference
Interactive exploration of RNA22 microRNA target predictions
10.1093/bioinformatics/bts615 · 2012 · External reference
RNAInter v4.0: RNA interactome repository with redefined confidence scoring system and improved accessibility
10.1093/nar/gkab997 · 2022 · External reference
TargetMiner: microRNA target prediction with systematic identification of tissue-specific negative examples
10.1093/bioinformatics/btp503 · 2009 · External reference
The biochemical basis of microRNA targeting efficacy
10.1126/science.aav1741 · 2019 · External reference
miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions
10.1093/nar/gkx1067 · 2018 · External reference
DIANA-LncBase v3: indexing experimentally supported miRNA targets on non-coding transcripts
2020 · External reference
Bone marrow derived mesenchymal stem cells enriched PCL-gelatin nanofiber scaffold for improved wound healing
2024 · External reference
YTHDF3-associated m6A regulation and cuproptosis-related gene expression in steroid-induced osteonecrosis of the femoral head
10.1007/s10735-025-10544-x · 2025 · External reference
The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications
10.1038/s12276-023-00944-y · 2023 · External reference
RGS1 stabilized by METTL3-mediated m6A modification promotes the tumorigenicity and macrophage M2 polarization in osteosarcoma
10.1016/j.jbo.2025.100705 · 2025 · External reference
METTL3-mediated m(6)A modification promotes intervertebral disc degeneration
10.1080/07853890.2025.2546670 · 2025 · External reference
The critical role of METTL3-mediated m(6)A RNA methylation in orchestrating musculoskeletal development: Underlying mechanisms and therapeutic perspectives
10.1016/j.tice.2025.103098 · 2025 · External reference
Unraveling the Role of N6-Methylation Modification: From Bone Biology to Osteoporosis
10.7150/ijms.108763 · 2025 · External reference
m(6)A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis
10.1038/s41420-020-00382-z · 2021 · External reference
LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC
10.1186/s13045-021-01123-0 · 2021 · External reference
m(6)A methyltransferase METTL3-mediated lncRNA FOXD2-AS1 promotes the tumorigenesis of cervical cancer
10.1016/j.omto.2021.07.004 · 2021 · External reference
Bone marrow mesenchymal stem cells-derived exosomal microRNA-19b-1-5p reduces proliferation and raises apoptosis of bladder cancer cells via targeting ABL2
10.1016/j.ygeno.2021.03.011 · 2021 · External reference
Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2
10.1186/s12964-023-01229-7 · 2023 · External reference
High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer
10.1007/s10620-018-5111-7 · 2018 · External reference
Overexpression of Abl2 predicts poor prognosis in hepatocellular carcinomas and is associated with cancer cell migration and invasion
10.2147/ott.s62348 · 2014 · External reference
Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery
10.1186/cc12786 · 2013 · External reference