References

Sphingolipids and their metabolism in physiology and disease

10.1038/nrm.2017.107 · 2018 · External reference

Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis

10.1074/jbc.m505712200 · 2005 · External reference

Novelty of sphingolipids in the central nervous system physiology and disease: focusing on the sphingolipid hypothesis of neuroinflammation and neurodegeneration

10.3390/ijms22147353 · 2021 · External reference

Diverse biological functions of sphingolipids in the CNS: ceramide and sphingosine regulate myelination in developing brain but stimulate demyelination during pathogenesis of multiple sclerosis

2017 · External reference

Sphingolipids and brain resident macrophages in neuroinflammation: an emerging aspect of nervous system pathology

10.1155/2013/309302 · 2013 · External reference

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

10.1038/nature15399 · 2015 · External reference

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

10.1038/nature15400 · 2015 · External reference

Serinc2 deficiency exacerbates sepsis-induced cardiomyopathy by enhancing necroptosis and apoptosis

10.1016/j.bcp.2023.115903 · 2023 · External reference

Phenome-wide association studies between SERINC2 and neuropsychiatric disorders

2024 · External reference

SERINC2-mediated serine metabolism promotes cervical cancer progression and drives T cell exhaustion

10.7150/ijbs.105572 · 2025 · External reference

Serinc2 drives the progression of cervical cancer through regulating Myc pathway

10.1002/cam4.70296 · 2024 · External reference

The emerging role of the serine incorporator protein family in regulating viral infection

2022 · External reference

SERINC2-knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma

2018 · External reference

Coelacanth SERINC2 inhibits HIV-1 infectivity and is counteracted by envelope glycoprotein from foamy virus

10.1128/jvi.00229-21 · 2021 · External reference

HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy

10.1074/jbc.ra120.014466 · 2020 · External reference

Structural basis for tetherin antagonism as a barrier to zoonotic lentiviral transmission

10.1016/j.chom.2019.08.002 · 2019 · External reference

The importance of serine metabolism in cancer

10.1083/jcb.201604085 · 2016 · External reference

A bipartite structural organization defines the SERINC family of HIV-1 restriction factors

10.1038/s41594-019-0357-0 · 2020 · External reference

Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway

10.1016/j.bbadis.2024.167650 · 2025 · External reference

Expression characteristics and biological significance of exosome-related genes in lung cancer

10.1007/s12672-025-03173-z · 2025 · External reference

MYC and metabolism on the path to cancer

10.1016/j.semcdb.2015.08.003 · 2015 · External reference

Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy

10.1111/cas.14862 · 2021 · External reference

Serine incorporator 2 (SERINC2) expression predicts an unfavorable prognosis of low-grade glioma (LGG): evidence from bioinformatics analysis

10.1007/s12031-020-01620-w · 2020 · External reference

Phosphatidylserine is a critical modulator for Akt activation

10.1083/jcb.201005100 · 2011 · External reference

Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation

10.1038/oncsis.2014.21 · 2014 · External reference

Integrative methylome and transcriptome characterization identifies SERINC2 as a tumor-driven gene for papillary thyroid carcinoma

10.3390/cancers15010243 · 2022 · External reference

New insights into the role of mTOR signaling in the cardiovascular system

10.1161/circresaha.117.311147 · 2018 · External reference

Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases

10.1074/jbc.ac119.007382 · 2019 · External reference

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

10.1038/nature21423 · 2017 · External reference

Molecular events in the cardiomyopathy of sepsis

10.2119/2007-00130.flierl · 2008 · External reference

Sepsis-induced cardiac dysfunction: a review of pathophysiology

10.4266/acc.2020.00248 · 2020 · External reference

Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury

10.1186/s12950-022-00306-x · 2022 · External reference

NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent

10.1016/j.drugalcdep.2013.02.006 · 2013 · External reference

SERINC2 increases the risk of bipolar disorder in the Chinese population

10.1002/da.23186 · 2021 · External reference

Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent

10.1097/fpc.0b013e328362f9f2 · 2013 · External reference

Whole-brain spatial distribution of serine incorporator 2 mRNA in adult C57BL/6J mice

10.1016/j.brainresbull.2025.111519 · 2025 · External reference

The distribution and function of phosphatidylserine in cellular membranes

10.1146/annurev.biophys.093008.131234 · 2010 · External reference

The mystery of membrane organization: composition, regulation and roles of lipid rafts

10.1038/nrm.2017.16 · 2017 · External reference

Effect of CTMP1 gene on pulmonary fibrosis

10.1007/s43188-024-00269-6 · 2025 · External reference