Research graph
References from Combining automated kinetic model selection with robust optimization and application to maximize cell-free production of UDP-GalNAc. Local targets link to admitted publications; unresolved targets remain external evidence.
Information theory and an extension of the maximum likelihood principle
1973 · External reference
eQuilibrator 3.0: a database solution for thermodynamic constant estimation
10.1093/nar/gkab1106 · 2022 · External reference
BASICO: a simplified Python interface to COPASI
10.21105/joss.05553 · 2023 · External reference
Supplementing glycosylation: a review of applying nucleotide-sugar precursors to growth medium to affect therapeutic recombinant protein glycoform distributions
10.1016/j.biotechadv.2018.06.008 · 2018 · External reference
DeepMoD: deep learning for model discovery in noisy data
10.1016/j.jcp.2020.109985 · 2021 · External reference
Discovering governing equations from data by sparse identification of nonlinear dynamical systems
10.1073/pnas.1517384113 · 2016 · External reference
Kinetic and structural properties of inorganic pyrophosphatase from the pathogenic bacterium Helicobacter pylori
10.1002/prot.21093 · 2006 · External reference
A critical comparison of cellular and cell-free bioproduction systems
10.1016/j.copbio.2019.05.003 · 2019 · External reference
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation
10.1038/srep28547 · 2016 · External reference
Unresolved reference
2014 · External reference
Experimentally implemented dynamic optogenetic optimization of ATPase expression using knowledge-based and gaussian-process-supported models
10.1016/j.procbio.2024.04.032 · 2024 · External reference
Cell-free biosynthesis meets dynamic optimization and control: a fed-batch framework
10.1016/j.ifacol.2023.01.021 · 2022 · External reference
ModelMage: a tool for automatic model generation, selection and management
2008 · External reference
Enzyme cascades for the synthesis of nucleotide sugars: updates to recent production strategies
10.1016/j.carres.2022.108727 · 2023 · External reference
Advanced enzymatic multigram-scale production of nucleotide sugars in a continuous fed-batch membrane reactor
10.1016/j.jbiotec.2024.09.001 · 2024 · External reference
Bayesian regression facilitates quantitative modeling of cell metabolism
10.1021/acssynbio.3c00662 · 2024 · External reference
On structural and practical identifiability: current status and update of results
2025 · External reference
Establishment of a cell-free multi-enzyme cascade for the synthesis of UDP-GalNAc
10.1016/j.nbt.2025.05.003 · 2025 · External reference
COPASI–a COmplex PAthway SImulator
10.1093/bioinformatics/btl485 · 2006 · External reference
Parameterization of cell-free systems with time-series data using KETCHUP
10.1371/journal.pcbi.1013724 · 2025 · External reference
Model-based optimization of cell-free enzyme cascades exemplified for the production of GDP-fucose
10.1016/j.ymben.2023.10.007 · 2024 · External reference
Regression and time series model selection in small samples
10.1093/biomet/76.2.297 · 1989 · External reference
Numerical matrices method for nonlinear System identification and description of dynamics of biochemical reaction networks
10.1529/biophysj.106.093344 · 2007 · External reference
Synthetic glycobiology: parts, systems, and applications
10.1021/acssynbio.0c00210 · 2020 · External reference
Profile likelihood in systems biology
10.1111/febs.12276 · 2013 · External reference
Growth media for E. coli
10.1016/b978-0-12-420067-8.00011-8 · 2013 · External reference
Bringing metabolic networks to life: convenience rate law and thermodynamic constraints
10.1186/1742-4682-3-41 · 2006 · External reference
Bayesian parameter estimation for dynamical models in systems biology
10.1371/journal.pcbi.1010651 · 2022 · External reference
Enzyme immobilization technologies and industrial applications
10.1021/acsomega.2c07560 · 2023 · External reference
Identification of N-Acetylhexosamine 1-Kinase in the complete Lacto-N-Biose I/Galacto-N-Biose metabolic pathway in Bifidobacterium longum
10.1128/aem.01425-07 · 2007 · External reference
A methodology for performing global uncertainty and sensitivity analysis in systems biology
10.1016/j.jtbi.2008.04.011 · 2008 · External reference
A dynamic kinetic model captures cell-free metabolism for improved butanol production
10.1016/j.ymben.2023.01.009 · 2023 · External reference
GRASP: a computational platform for building kinetic models of cellular metabolism
10.1093/bioadv/vbac066 · 2022 · External reference
DASyR-LLM: Domain-Aware symbolic regression with LLMs for kinetic model Discovery
2026 · External reference
10.1128/jb.176.18.5788-5795.1994
10.1128/jb.176.18.5788-5795.1994 · 1994 · External reference
Glycoconjugate vaccines: current approaches towards faster vaccine design
10.1080/14760584.2019.1657012 · 2019 · External reference
Parameter estimation and uncertainty quantification for systems biology models
10.1016/j.coisb.2019.10.006 · 2019 · External reference
A multiscale hybrid modelling methodology for cell cultures enabled by enzyme-constrained dynamic metabolic flux analysis under uncertainty
10.1016/j.ymben.2024.10.013 · 2024 · External reference
A primer on model selection using the Akaike information criterion
10.1016/j.idm.2019.12.010 · 2020 · External reference
Bayesian model comparison and parameter inference in systems biology using nested sampling
10.1371/journal.pone.0088419 · 2014 · External reference
Prediction of dynamical systems by symbolic regression
10.1103/physreve.94.012214 · 2016 · External reference
Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood
10.1093/bioinformatics/btp358 · 2009 · External reference
ATP as effector of inorganic pyrophosphatase of Escherichia coli. Identification of the binding site for ATP
10.1134/s0006297907010117 · 2007 · External reference
Construction of feasible and accurate kinetic models of metabolism: a Bayesian approach
10.1038/srep29635 · 2016 · External reference
Recent trends on hybrid modeling for Industry 4.0
10.1016/j.compchemeng.2021.107365 · 2021 · External reference
Automated ensemble modeling with modelMaGe: analyzing feedback mechanisms in the Sho1 branch of the HOG pathway
10.1371/journal.pone.0014791 · 2011 · External reference
Recognizing structural nonidentifiability: when experiments do not provide information about important parameters and misleading models can still have great fit
10.1111/risa.13386 · 2020 · External reference
Estimating the dimension of a model
10.1214/aos/1176344136 · 1978 · External reference
A combined experimental and modelling approach for the Weimberg pathway optimisation
10.1038/s41467-020-14830-y · 2020 · External reference
Getting the Most out of enzyme cascades: strategies to optimize in vitro multi-enzymatic reactions
10.3390/catal11101183 · 2021 · External reference
Three-level hybrid modeling for systematic optimization of biocatalytic synthesis: α-glucosyl glycerol production by enzymatic trans-glycosylation from sucrose
10.1002/bit.27878 · 2021 · External reference
One-pot heterogeneous biocatalysis under thermal decay for fructose production from lactose using Co-Immobilized enzymes: modeling and simulation
10.1002/cctc.202301240 · 2024 · External reference
Further analysis of the data by Akaike's information criterion and the finite corrections
10.1080/03610927808827599 · 1978 · External reference
Construction of an artificial In vitro synthetic enzymatic platform for upgrading low-cost starch to value-added disaccharides
10.1021/acs.jafc.0c06936 · 2021 · External reference
The multiple activities of polyphosphate kinase of Escherichia coli and their subunit structure determined by radiation target analysis
10.1074/jbc.275.6.3977 · 2000 · External reference
Uridine-cytidine kinase from Escherichia coli
1978 · External reference
Prediction uncertainty assessment of a systems biology model requires a sample of the full probability distribution of its parameters
10.7717/peerj.433 · 2014 · External reference
Parameter uncertainty in biochemical models described by ordinary differential equations
10.1016/j.mbs.2013.03.006 · 2013 · External reference
Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions
10.1186/s12918-017-0484-3 · 2018 · External reference
From lab bench to formulated ingredient: characterization, production, and commercialization of human milk oligosaccharides
10.1016/j.jff.2020.104052 · 2020 · External reference
On structural and practical identifiability
10.1016/j.coisb.2021.03.005 · 2021 · External reference
A kinetic model of one-pot rapid biotransformation of cellobiose from sucrose catalyzed by three thermophilic enzymes
10.1016/j.ces.2016.11.047 · 2017 · External reference
