Research graph
References from Transcriptomic and genetic evidence highlights EHHADH in a FUNDC1-associated mitochondrial network in diabetic nephropathy. Local targets link to admitted publications; unresolved targets remain external evidence.
Prevalence of diabetic nephropathy among patients with type 2 diabetes mellitus in China: a meta-analysis of observational studies
10.1155/2020/2315607 · 2020 · External reference
Tubular injury in diabetic kidney disease: early diagnosis and intervention strategies
10.1002/dmrr.70098 · 2025 · External reference
An update on renal tubular injury as related to glycolipid metabolism in diabetic kidney disease
2025 · External reference
An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling
10.1016/j.ejphar.2024.176376 · 2024 · External reference
Mitochondria in diabetic kidney disease
10.3390/cells10112945 · 2021 · External reference
Endoplasmic reticulum stress in diabetic nephrology: regulation, pathological role, and therapeutic potential
10.1155/2021/7277966 · 2021 · External reference
AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice
10.1038/s41419-021-04184-8 · 2021 · External reference
Engineered RGD-Treg-Exos targeted delivery of miR-218-5p to activate mitophagy and attenuate podocyte injury in diabetic kidney disease
2025 · External reference
Endothelial FUNDC1 regulates metabolic reprogramming and the obesity-diabetes transition through the SIRT3/GATA2/endothelin-1 axis
2026 · External reference
Autophagy and mitophagy in diabetic retinopathy: the effects and mechanism of action on the neurovascular unit
10.1016/j.exer.2025.110802 · 2026 · External reference
Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission
10.1016/j.redox.2019.101415 · 2020 · External reference
Decoding coffee's chlorogenic acid: genetic-network pharmacology insights on kidney stones
10.1007/s00240-025-01776-3 · 2025 · External reference
Mitophagy in diabetic kidney disease
10.3389/fcell.2021.778011 · 2021 · External reference
Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives
2023 · External reference
Src activation aggravates podocyte injury in diabetic nephropathy via suppression of FUNDC1-Mediated mitophagy
2022 · External reference
EHHADH deficiency regulates pexophagy and accelerates tubulointerstitial injury in diabetic kidney disease
10.1038/s41420-024-02066-4 · 2024 · External reference
Targeting lipid metabolic reprogramming to alleviate diabetic kidney disease: molecular insights and therapeutic strategies
2025 · External reference
A fast and powerful eQTL weighted method to detect genes associated with complex trait using GWAS summary data
10.1002/gepi.22297 · 2020 · External reference
Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice
10.1080/15548627.2021.1985257 · 2022 · External reference
METTL14 knockdown mitigates HG-induced HK-2 cell apoptosis, inflammation, and ferroptosis by promoting SLC40A1
10.1186/s40001-026-03844-9 · 2026 · External reference
Identification of the expression and clinical significance of E2F family in clear cell renal cell carcinoma
10.2147/ijgm.s349723 · 2022 · External reference
