Research graph
References from Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method. Local targets link to admitted publications; unresolved targets remain external evidence.
Trifluoroacetic acid pretreatment reproducibly disaggregates the amyloid beta-peptide
10.3109/13506129709003835 · 1997 · External reference
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
10.1074/jbc.m210207200 · 2003 · External reference
Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer’s disease
10.1111/j.1471-4159.1986.tb08501.x · 1986 · External reference
An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies
10.1016/j.jneumeth.2010.05.001 · 2010 · External reference
Detecting abeta*56 oligomers in brain tissues
10.1007/978-1-60761-744-0_4 · 2011 · External reference
Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples
10.1007/s00401-013-1083-z · 2013 · External reference
A beta oligomers – a decade of discovery
10.1111/j.1471-4159.2006.04426.x · 2007 · External reference
Amyloid-beta oligomers: possible roles as key neurotoxins in Alzheimer’s Disease
10.1002/msj.20160 · 2010 · External reference
Twenty years of Alzheimer’s disease-causing mutations
10.1111/j.1471-4159.2011.07575.x · 2012 · External reference
Soluble Abeta oligomer production and toxicity
10.1111/j.1471-4159.2011.07478.x · 2012 · External reference
Alzheimer’s disease: the amyloid cascade hypothesis
10.1126/science.1566067 · 1992 · External reference
Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment
10.1002/ana.410300410 · 1991 · External reference
Correlations of synaptic and pathological markers with cognition of the elderly
10.1016/0197-4580(95)00013-5 · 1995 · External reference
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer’s disease
10.1002/1531-8249(199912)46:6<860::aid-ana8>3.0.co;2-m · 1999 · External reference
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer’s disease
10.1016/s0002-9440(10)65184-x · 1999 · External reference
The levels of soluble versus insoluble brain Abeta distinguish Alzheimer’s disease from normal and pathologic aging
10.1006/exnr.1999.7085 · 1999 · External reference
The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics
10.1126/science.1072994 · 2002 · External reference
M.R.I. antemortem findings correlate with hippocampal neuropathology in typical aging and dementia
10.1212/wnl.58.5.750 · 2002 · External reference
Evaluating early dementia with and without assessment of regional cerebral metabolism by PET: a comparison of predicted costs and benefits
2002 · External reference
Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF
10.1212/wnl.52.8.1555 · 1999 · External reference
Association between CSF biomarkers and incipient Alzheimer’s disease in patients with mild cognitive impairment: a follow-up study
10.1016/s1474-4422(06)70355-6 · 2006 · External reference
Imaging brain amyloid in Alzheimer’s disease with Pittsburgh Compound-B
10.1002/ana.20009 · 2004 · External reference
Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease
10.1097/00019442-200201000-00004 · 2002 · External reference
Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS-ADRDA criteria
10.1016/s1474-4422(07)70178-3 · 2007 · External reference
The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
10.1016/j.jalz.2011.03.005 · 2011 · External reference
Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay
10.1002/ana.20524 · 2005 · External reference
Oligomerization partially explains the lowering of Abeta42 in Alzheimer’s disease cerebrospinal fluid
10.1159/000225376 · 2009 · External reference
Oligomerizaiton and fibril asssembly of the amyloid-beta protein
10.1016/s0925-4439(00)00030-2 · 2000 · External reference
Sensitive ELISA detection of amyloid-beta protofibrils in biological samples
10.1111/j.1471-4159.2007.04759.x · 2007 · External reference
Characterisation of two antibodies to oligomeric Abeta and their use in ELISAs on human brain tissue homogenates
10.1016/j.jneumeth.2008.09.002 · 2009 · External reference
A Luminex assay detects amyloid beta oligomers in Alzheimer’s disease cerebrospinal fluid
10.1371/journal.pone.0067898 · 2013 · External reference
New ELISAs with high specificity for soluble oligomers of amyloid beta-protein detect natural Abeta oligomers in human brain but not CSF
10.1016/j.jalz.2012.11.005 · 2013 · External reference
An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer’s disease
10.1016/j.nbd.2009.08.007 · 2009 · External reference
High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients
10.1096/fj.09-150359 · 2010 · External reference
A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
10.1001/archneurol.2008.565 · 2009 · External reference
Evaluating amyloid-beta oligomers in cerebrospinal fluid as a biomarker for Alzheimer’s disease
10.1371/journal.pone.0066381 · 2013 · External reference
A sensitive abeta oligomer assay discriminates Alzheimer’s and aged control cerebrospinal fluid
10.1523/jneurosci.1675-13.2014 · 2014 · External reference
Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer’s disease
10.1073/pnas.0409336102 · 2005 · External reference
The amyloid-beta oligomer count in cerebrospinal fluid is a biomarker for Alzheimer’s disease
10.3233/jad-122047 · 2013 · External reference
Detection of amyloid-beta oligomers in human cerebrospinal fluid by flow cytometry and fluorescence resonance energy transfer
10.3233/jad-2007-11114 · 2007 · External reference
