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References from Serial In Vivo Passage of Acanthamoeba lugdunensis Is Associated with Altered Transcription and Increased Blood–Brain Barrier Permeability in Mice. Local targets link to admitted publications; unresolved targets remain external evidence.
From grazing resistance to pathogenesis: the coincidental evolution of virulence factors
10.1371/journal.pone.0011882 · 2010 · External reference
Acanthamoeba interactions with human brain microvascular endothelial cells
10.1016/j.micpath.2003.07.001 · 2003 · External reference
Extracellular proteases of Acanthamoeba castellanii (encephalitis isolate belonging to T1 genotype) contribute to increased permeability in an in vitro model of the human blood-brain barrier
10.1016/j.jinf.2004.09.001 · 2005 · External reference
Unresolved reference
External reference
Case Report: Granulomatous Amebic Encephalitis due to Acanthamoeba spp. in an Immunocompetent Pediatric Patient
10.4269/ajtmh.21-0129 · 2021 · External reference
Amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by streptococcal IgA1 proteases
10.1128/iai.71.3.1462-1469.2003 · 2003 · External reference
Challenges in Diagnosing and Treating Granulomatous Amebic Encephalitis: A Case Report of Fatal Acanthamoeba spp. Encephalitis in an Immunocompetent Patient
10.14740/jnr854 · 2025 · External reference
Controlling the false discovery rate: a practical and powerful approach to multiple testing
10.1111/j.2517-6161.1995.tb02031.x · 1995 · External reference
Trimmomatic: a flexible trimmer for Illumina sequence data
10.1093/bioinformatics/btu170 · 2014 · External reference
Identification and Distribution of Acanthamoeba Species Genotypes Associated with Nonkeratitis Infections
10.1128/jcm.43.4.1689-1693.2005 · 2005 · External reference
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
10.1016/0003-2697(76)90527-3 · 1976 · External reference
Accidental virulence, cryptic pathogenesis, martians, lost hosts, and the pathogenicity of environmental microbes
10.1128/ec.00308-07 · 2007 · External reference
Presence and diversity of free-living amoebae and their potential application as water quality indicators. Parasites
10.3347/phd.24020 · 2024 · External reference
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
10.1186/gb-2013-14-2-r11 · 2013 · External reference
Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases
10.4103/jfmpc.jfmpc_1010_19 · 2020 · External reference
IgA: Structure, Function, and Developability
10.3390/antib8040057 · 2019 · External reference
Genotype distribution of Acanthamoeba in keratitis: a systematic review
10.1007/s00436-021-07261-1 · 2021 · External reference
Experimental evolution of parasites
10.1126/science.282.5393.1432 · 1998 · External reference
An efficient algorithm for large-scale detection of protein families
10.1093/nar/30.7.1575 · 2002 · External reference
Cloning and Characterization of a Novel Mannose-binding Protein of Acanthamoeba
10.1074/jbc.m402334200 · 2004 · External reference
Claudin-5: gatekeeper of neurological function
10.1186/s12987-019-0123-z · 2019 · External reference
Microorganisms resistant to free-living amoebae
10.1128/cmr.17.2.413-433.2004 · 2004 · External reference
A comparative genomic approach to determine the virulence factors and horizontal gene transfer events of clinical Acanthamoeba isolates
10.1128/spectrum.00025-22 · 2022 · External reference
Amebic encephalitis and meningoencephalitis: an update on epidemiology, diagnostic methods, and treatment
10.1097/qco.0000000000000923 · 2023 · External reference
Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates
10.1016/0003-2697(80)90338-3 · 1980 · External reference
Epidemiology of and genetic factors associated with Acanthamoeba keratitis
10.3390/pathogens13020142 · 2024 · External reference
KEGG: Kyoto Encyclopedia of Genes and Genomes
10.1093/nar/28.1.27 · 2000 · External reference
Acanthamoeba invasion of the central nervous system
10.1016/j.ijpara.2006.11.010 · 2007 · External reference
Acanthamoeba affects the integrity of human brain microvascular endothelial cells and degrades the tight junction proteins
10.1016/j.ijpara.2009.06.004 · 2009 · External reference
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
10.1038/s41587-019-0201-4 · 2019 · External reference
Purification and Characterization of a 33 kDa Serine Protease From Acanthamoeba lugdunensis KA/E2 Isolated from a Korean Keratitis Patient
10.3347/kjp.2003.41.4.189 · 2003 · External reference
Infections caused by free-living amoebae
10.1128/jcm.00228-21 · 2022 · External reference
Validation of reference genes for the normalization of RT-qPCR gene expression in Acanthamoeba spp
10.1038/s41598-020-67035-0 · 2020 · External reference
Molecular Phylogeny of Acanthamoeba
10.3347/kjp.2009.47.s.s21 · 2009 · External reference
Immunopathogenicity of Acanthamoeba spp. in the brain and lungs
10.3390/ijms22031261 · 2021 · External reference
The Brief Case: Acanthamoeba meningoencephalitis in a transplant recipient
10.1128/jcm.00350-24 · 2025 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method
10.1006/meth.2001.1262 · 2001 · External reference
An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment
10.1051/parasite/2015010 · 2015 · External reference
Characterization of novel extracellular proteases produced by Acanthamoeba castellanii after contact with human corneal epithelial cells and their relevance to pathogenesis
10.1186/s13071-024-06304-7 · 2024 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Selection for high and low virulence in the malaria parasite Plasmodium chabaudi
10.1098/rspb.1999.0699 · 1999 · External reference
Proteases of Acanthamoeba
10.1007/s00436-023-08059-z · 2024 · External reference
Off the hook--how bacteria survive protozoan grazing
10.1016/j.tim.2005.05.009 · 2005 · External reference
Genotyping of Acanthamoeba spp. isolated from patients with granulomatous amoebic encephalitis
10.4103/ijmr.ijmr_1564_17 · 2018 · External reference
Microarray and KOG analysis of Acanthamoeba healyi genes up-regulated by mouse-brain passage
10.1016/j.exppara.2014.05.012 · 2014 · External reference
Purification, Axenic Cultivation, and Description of a Soil Amoeba, Acanthamoeba Sp
10.1111/j.1550-7408.1957.tb02505.x · 1957 · External reference
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
10.1038/nbt.3122 · 2015 · External reference
Mutanase from Paenibacillus sp. MP-1 produced inductively by fungal alpha-1,3-glucan and its potential for the degradation of mutan and Streptococcus mutans biofilm
10.1007/s10529-010-0346-1 · 2010 · External reference
Cytoscape: a software environment for integrated models of biomolecular interaction networks
10.1101/gr.1239303 · 2003 · External reference
DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)
10.1093/nar/gkac194 · 2022 · External reference
Identification and properties of proteases from an Acanthamoeba isolate capable of producing granulomatous encephalitis
10.1186/1471-2180-6-42 · 2006 · External reference
Challenges and advances in the medical treatment of granulomatous amebic encephalitis
2024 · External reference
Molecular Characterization of a Rhodotorula-lytic Enzyme from Paecilomyces lilacinus Having beta-1,3-Mannanase Activity
10.1271/bbb.68.757 · 2004 · External reference
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
Biological characteristics and pathogenicity of Acanthamoeba
2023 · External reference
Acanthamoeba healyi: Expressed gene profiles with enhanced virulence after mouse-brain passage
10.1016/j.exppara.2009.07.012 · 2009 · External reference
Molecular characterization of bacterial endosymbionts of Acanthamoeba isolates from infected corneas of Korean patients
10.3347/kjp.2007.45.1.1 · 2007 · External reference
Measuring blood-brain-barrier permeability using Evans blue in mice
10.21769/bioprotoc.1548 · 2015 · External reference
Laboratory investigation of Acanthamoeba lugdunensis from patients with keratitis
10.1167/iovs.03-0433 · 2004 · External reference
Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2
10.1186/s12974-018-1287-1 · 2018 · External reference
