Research graph
References from Evaluation of antitrichomonal activity of coffeewaste compounds against different Trichomonas vaginalis strains: An in vitro and in silico study. Local targets link to admitted publications; unresolved targets remain external evidence.
Worldwide prevalence of protozoans and helminths among disabled people: a systematic review and meta-analysis
10.1186/s12889-025-24074-4 · 2025 · External reference
Microbiome and human health: current understanding, engineering, and enabling technologies
10.1021/acs.chemrev.2c00431 · 2023 · External reference
A review on Trichomonas vaginalis infections in women from Africa
10.4102/sajid.v36i1.254 · 2021 · External reference
The past, present, and future in the diagnosis of a neglected sexually transmitted infection: trichomoniasis
10.3390/pathogens13020126 · 2024 · External reference
Trichomonas vaginalis: a review of epidemiologic, clinical and treatment issues
10.1186/s12879-015-1055-0 · 2015 · External reference
A review on metronidazole: an old warhorse in antimicrobial chemotherapy
10.1017/s0031182017002025 · 2019 · External reference
Resistência ao metronidazol em isolados clínicos de Trichomonas vaginalis
2024 · External reference
Multi-drug resistant trichomoniasis: a case report
10.1016/j.ijantimicag.2021.106421.59 · 2021 · External reference
Comportamento das exportações da agroindústria brasileira do café e interações com agentes produtivos
2021 · External reference
From coffee waste to active ingredient for cosmetic applications
10.3390/ijms24108516 · 2023 · External reference
Valorization of coffee by-products in the industry, a vision towards circular economy
10.1007/s42452-024-06085-9 · 2024 · External reference
Enhancement of antioxidant properties from green coffee as promising ingredient for food and cosmetic industries
10.1016/j.bcab.2018.07.011 · 2018 · External reference
Antioxidant extracts of coffee leaves and its active ingredient 5-caffeoylquinic acid reduce chemically-induced inflammation in mice
10.1016/j.indcrop.2018.09.027 · 2018 · External reference
Chemical characterisation by UPLC‐Q‐ToF‐MS/MS and antibacterial potential of Coffea arabica L. leaves: a coffee by‐product
10.1002/pca.3157 · 2022 · External reference
Synthesis of quinic acid‐derived sialylmimetics and their effects on T. cruzi and trans ‐ Sialidase
10.1002/slct.202501917 · 2025 · External reference
Inhibition studies of the protozoan α-carbonic anhydrase from Trypanosoma cruzi with phenols
10.1080/14756366.2022.2119965 · 2022 · External reference
Amoebicidal activity of caffeine and maslinic acid by the induction of programmed cell death in Acanthamoeba
10.1128/aac.02660-16 · 2017 · External reference
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase
10.1111/cbdd.13391 · 2019 · External reference
Caffeic acid has antipromastigote activity by apoptosis-like process; and anti-amastigote by TNF-α/ROS/NO production and decreased of iron availability
10.1016/j.phymed.2018.12.035 · 2019 · External reference
Cinnamides target Leishmania amazonensis arginase selectively
10.3390/molecules25225271 · 2020 · External reference
Caffeic acid reduces Toxoplasma gondii proliferation in human extravillous trophoblast cells (HTR8/SVneo) through induction of pro-inflammatory cytokines and a death process suggestive of apoptosis
10.1016/j.micinf.2025.105584 · 2025 · External reference
Antiparasitic and antimicrobial activity of Ipomoea palmata against Toxoplasma gondii and Staphylococcus aureus : correlation with major phenolics identified by HPLC
10.1080/21691401.2025.2494796 · 2025 · External reference
Efficacy of mangiferin against Cryptosporidium parvum in a neonatal mouse model
10.1007/s00436-006-0165-4 · 2006 · External reference
Unresolved reference
1995 · External reference
The establishment of various trichomonads of animals and man in axenic cultures
10.2307/3274682 · 1957 · External reference
Trichomonas vaginalis kills and eats – evidence for phagocytic activity as a cytopathic effect
10.1017/s0031182009991041 · 2010 · External reference
Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases
10.1002/pro.2904 · 2016 · External reference
Development and validation of a genetic algorithm for flexible docking
10.1006/jmbi.1996.0897 · 1997 · External reference
General and targeted statistical potentials for protein–ligand interactions
10.1002/prot.20588 · 2005 · External reference
DockThor-VS: a free platform for receptor-ligand virtual screening
10.1016/j.jmb.2024.168548 · 2024 · External reference
New machine learning and physics-based scoring functions for drug discovery
10.1038/s41598-021-82410-1 · 2021 · External reference
Recent advances in the prediction of pharmacokinetics properties in drug design studies: a review
10.1002/cmdc.202100542 · 2022 · External reference
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
10.1038/srep42717 · 2017 · External reference
pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
10.1021/acs.jmedchem.5b00104 · 2015 · External reference
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
10.1016/0022-1759(83)90303-4 · 1983 · External reference
Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas
10.1016/j.bmc.2010.07.008 · 2010 · External reference
Impact of hydroxychloroquine-loaded polyurethane intravaginal rings on Lactobacilli
10.1128/aac.01819-15 · 2015 · External reference
Design and synthesis of coumarin–glyoxal hybrids for spermicidal and antimicrobial actions: a dual approach to contraception
10.1039/c6ra12156j · 2016 · External reference
Combining a synthetic spermicide with a natural trichomonacide for safe, prophylactic contraception
10.1093/humrep/det423 · 2014 · External reference
Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses
10.1186/s13071-020-3923-8 · 2020 · External reference
Quinolines-1,2,3-triazolylcarboxamides exhibits antiparasitic activity in Trichomonas vaginalis
10.1016/j.biori.2019.06.003 · 2019 · External reference
Anti-Trichomonas vaginalis activity of chalcone and amino-analogues
10.1007/s00436-018-6164-4 · 2019 · External reference
Deciphering evolutionary trajectories of lactate dehydrogenases provides new insights into allostery
10.1093/molbev/msad223 · 2023 · External reference
Global burden of trichomoniasis: current status, trends, and projections (1990–2021)
2025 · External reference
Semisynthetic tetramate-containing fungal metabolites with activity against trichomonas vaginalis and Mycoplasma genitalium
10.1021/acsmedchemlett.4c00386 · 2024 · External reference
Exploring novel pyrazole-nitroimidazole hybrids: synthesis and antiprotozoal activity against the human pathogen trichomonas vaginalis
10.1016/j.bmc.2024.117679 · 2024 · External reference
Deazapurine nucleoside analogues for the treatment of trichomonas vaginalis
10.1021/acsinfecdis.1c00075 · 2021 · External reference
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
10.1080/14756366.2022.2041629 · 2022 · External reference
Potato peels and their bioactive glycoalkaloids and phenolic compounds inhibit the growth of pathogenic trichomonads
10.1021/acs.jafc.8b01726 · 2018 · External reference
Population structure and genetic diversity of Trichomonas vaginalis clinical isolates in Australia and Ghana
10.1016/j.meegid.2020.104318 · 2020 · External reference
Population structure and genetic diversity of the parasite Trichomonas vaginalis in Bristol, UK
10.1016/j.meegid.2015.06.006 · 2015 · External reference
Anti-Trichomonas vaginalis activity of betulinic acid derivatives
10.1016/j.biopha.2016.09.064 · 2016 · External reference
Anti-Trichomonas vaginalis activity from triterpenoid derivatives
10.1007/s00436-014-3955-0 · 2014 · External reference
The natural iron chelators' ferulic acid and caffeic acid rescue mice's brains from side effects of iron overload
10.3389/fneur.2022.951725 · 2022 · External reference
Antioxidant activity of caffeic acid against iron-induced free radical Generation—A chemical approach
2015 · External reference
A systematic review of the literature on mechanisms of 5-nitroimidazole resistance in Trichomonas vaginalis
10.1017/s0031182020001237 · 2020 · External reference
In vitro activity of hexadecylphosphocholine (miltefosine) against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis
10.1093/jac/dki417 · 2006 · External reference
Hydrogenosome morphological variation induced by fibronectin and other drugs in Trichomonas vaginalis and Tritrichomonas foetus
10.1007/s004360000329 · 2001 · External reference
Biogenesis of autophagosome in trichomonas vaginalis during macroautophagy induced by rapamycin-treatment and iron or glucose starvation conditions
10.1111/jeu.12712 · 2019 · External reference
Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis
10.1099/00221287-148-8-2467 · 2002 · External reference
Dissecting the transcriptomes of multiple metronidazole-resistant and sensitive trichomonas vaginalis strains identified distinct genes and pathways associated with drug resistance and cell death
10.3390/biomedicines9121817 · 2021 · External reference
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
10.1016/j.addr.2012.09.019 · 2012 · External reference
Molecular properties that influence the oral bioavailability of drug candidates
10.1021/jm020017n · 2002 · External reference
Understanding drug skin permeation enhancers using molecular dynamics simulations
10.1021/acs.jcim.3c00625 · 2023 · External reference
Caffeine in liver diseases: pharmacology and toxicology
10.3389/fphar.2022.1030173 · 2022 · External reference
Acute kidney injury and hepatitis associated with energy drink consumption: a case report
10.1186/s13256-019-2340-0 · 2020 · External reference
Rare cause of acute hepatitis: a common energy drink
10.1136/bcr-2016-216612 · 2016 · External reference
Acute liver failure following one year of daily consumption of a sugar-free energy drink
10.14309/crj.2014.57 · 2014 · External reference