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References from Diagnostic performance of a baculovirus-expressed Tc-CPC–polyhedrin fusion protein in chronic Chagas disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2026 · External reference
Characterization of Latin American migrants at risk for Trypanosoma cruzi infection in a non-endemic setting. Insights into initial evaluation of cardiac and digestive involvement
10.1371/journal.pntd.0011330 · 2023 · External reference
Retrospect, advances and challenges in chagas disease diagnosis: a comprehensive review
2024 · External reference
2nd Brazilian consensus on chagas disease, 2015
10.1590/0037-8682-0505-2016 · 2016 · External reference
Chagas disease
10.1016/s0140-6736(17)31612-4 · 2018 · External reference
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Estimativa de prevalência de doença de Chagas crônica nos municípios brasileiros
10.26633/rpsp.2024.28 · 2024 · External reference
Secretaria de Vigilância em Saúde e Ambiente. Boletim epidemiológico: doença de Chagas. Brasília
2024 · External reference
Cardiac and digestive forms of chronic chagas disease in Brazilian social welfare, 2004-2016
10.47626/1679-4435-2022-1038 · 2023 · External reference
Evaluation and treatment of chagas disease in the United States
10.1001/jama.298.18.2171 · 2007 · External reference
Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American heart association
10.1161/cir.0000000000000599 · 2018 · External reference
Mortality from neglected tropical diseases in Brazil, 2000–2011
10.2471/blt.15.152363 · 2016 · External reference
Evaluation of the chagas Western blot IgG assay for the diagnosis of chagas disease
10.3390/pathogens10111455 · 2021 · External reference
Recombinant proteins as promising antigens applied to the immunodiagnosis of chagas disease: a scoping review
10.3389/fmicb.2024.1420226 · 2024 · External reference
Detection of anti-Trypanosoma cruzi antibodies by chimeric antigens in chronic Chagas disease-individuals from endemic South American countries
10.1371/journal.pone.0215623 · 2019 · External reference
Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
10.1371/journal.pntd.0007545 · 2019 · External reference
Highly accurate chimeric proteins for the serological diagnosis of chronic chagas disease: a latent class analysis
10.4269/ajtmh.17-0727 · 2018 · External reference
Rapid immunochromatographic tests for the diagnosis of chronic chagas disease in at-risk populations: a systematic review and meta-analysis
10.1371/journal.pntd.0007271 · 2019 · External reference
Easily purified baculovirus/insect-system-expressed recombinant hepatitis B virus surface antigen fused to the N- or C-terminus of polyhedrin
10.1007/s00705-021-05305-6 · 2022 · External reference
Hyper-enhanced production of foreign recombinant protein by fusion with the partial polyhedrin of nucleopolyhedrovirus
10.1371/journal.pone.0060835 · 2013 · External reference
Baculovirus as versatile vectors for protein expression in insect and mammalian cells
10.1038/nbt1095 · 2005 · External reference
Proteinases of trypanosoma cruzi: potential targets for the chemotherapy of chagas disease
10.2174/1568026023392995 · 2002 · External reference
The peptidases of trypanosoma cruzi: digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death
10.1016/j.bbapap.2011.05.011 · 2012 · External reference
Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection
10.1084/jem.188.4.725 · 1998 · External reference
10.1007/978-0-387-78267-6_11
10.1007/978-0-387-78267-6_11 · External reference
The presence of complex-type oligosaccharides at the C-terminal domain glycosylation site of some molecules of cruzipain
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Protein glucosylation and its role in protein folding
10.1146/annurev.biochem.69.1.69 · 2000 · External reference
Quantitative proteomic and phosphoproteomic analysis of Trypanosoma cruzi amastigogenesis
10.1074/mcp.m114.040329 · 2014 · External reference
Cell surface proteome analysis of human-hosted Trypanosoma cruzi life stages
10.1021/pr401120y · 2014 · External reference
Proteases in parasitic diseases
10.1146/annurev.pathol.1.110304.100151 · 2006 · External reference
The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database
10.1093/nar/gkx1134 · 2018 · External reference
Thirty years of baculovirus–insect cell protein expression: from dark horse to mainstream technology
10.1099/vir.0.067108-0 · 2015 · External reference
The baculovirus expression vector system: a commercial manufacturing platform for viral vaccines and gene therapy vectors
10.1002/biot.201400438 · 2015 · External reference
Biotechnological applications of occlusion bodies of baculoviruses
10.1007/s00253-018-9130-2 · 2018 · External reference
VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023
10.1093/nar/gkad1003 · 2024 · External reference
TriTrypDB: an integrated functional genomics resource for kinetoplastida
10.1371/journal.pntd.0011058 · 2023 · External reference
SignalP 6.0 predicts all five types of signal peptides using protein language models
10.1038/s41587-021-01156-3 · 2022 · External reference
Unresolved reference
2017 · External reference
Prediction of post‐translational glycosylation and phosphorylation of proteins from the amino acid sequence
10.1002/pmic.200300771 · 2004 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
AlphaFold protein structure database in 2024: providing structure coverage for over 214 million protein sequences
10.1093/nar/gkad1011 · 2024 · External reference
AlphaFold protein structure database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
10.1093/nar/gkab1061 · 2022 · External reference
3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources
10.1093/gigascience/giac118 · 2022 · External reference
ColabFold: making protein folding accessible to all
10.1038/s41592-022-01488-1 · 2022 · External reference
Next-generation IEDB tools: a platform for epitope prediction and analysis
10.1093/nar/gkae407 · 2024 · External reference
scp>BepiPred</scp> ‐3.0: improved b‐cell epitope prediction using protein language models
10.1002/pro.4497 · 2022 · External reference
DiscoTope-3.0: improved B-cell epitope prediction using inverse folding latent representations
10.3389/fimmu.2024.1322712 · 2024 · External reference
CHARMM‐GUI: a web‐based graphical user interface for CHARMM
10.1002/jcc.20945 · 2008 · External reference
CHARMM-GUI glycan modeler for modeling and simulation of carbohydrates and glycoconjugates
10.1093/glycob/cwz003 · 2019 · External reference
CHARMM-GUI PDB reader and manipulator: covalent ligand modeling and simulation
10.1016/j.jmb.2024.168554 · 2024 · External reference
A PMR1‐like calcium ATPase of Aspergillus fumigatus : cloning, identification and functional expression in S. cerevisiae
10.1002/yea.1280 · 2005 · External reference
Mitochondrial function in the yeast form of the pathogenic fungus Paracoccidioides brasiliensis
10.1007/s10863-008-9163-9 · 2008 · External reference
A baculovirus-mediated strategy for full-length plant virus coat protein expression and purification
10.1186/1743-422x-10-262 · 2013 · External reference
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
10.1038/227680a0 · 1970 · External reference
Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection
10.1371/journal.pntd.0002750 · 2014 · External reference
Schistosome syntenin partially protects vaccinated mice against Schistosoma mansoni infection
10.1371/journal.pntd.0003107 · 2014 · External reference
Schistosoma mansoni SmKI-1 or its C-Terminal fragment induces partial protection against S. mansoni infection in mice
10.3389/fimmu.2018.01762 · 2018 · External reference
Mutant Brucella abortus membrane fusogenic protein induces protection against challenge infection in mice
10.1128/iai.02790-14 · 2015 · External reference
The acute phase of Trypanosoma cruzi infection is attenuated in 5-Lipoxygenase-Deficient mice
10.1155/2014/893634 · 2014 · External reference
Cruzipain, a major Trypanosoma cruzi antigen, conditions the host immune response in favor of parasite
10.1002/1521-4141(200204)32:4<1003::aid-immu1003>3.0.co;2-p · 2002 · External reference
ExPASy: the proteomics server for in-depth protein knowledge and analysis
10.1093/nar/gkg563 · 2003 · External reference
Cysteine cathepsins: from structure, function and regulation to new frontiers
10.1016/j.bbapap.2011.10.002 · 2012 · External reference
Update on relevant trypanosome peptidases: validated targets and future challenges
10.1016/j.bbapap.2020.140577 · 2021 · External reference
Cysteine proteases as validated targets for the treatment of neglected and poverty-related parasitic diseases
10.3390/ijms241210097 · 2023 · External reference
Evaluation of cysteine protease C of Leishmania donovani in comparison with glycoprotein 63 and elongation factor 1α for diagnosis of human visceral leishmaniasis and for posttreatment follow-up response
10.1128/jcm.00213-20 · 2020 · External reference
Relocation of the attTn7 transgene insertion site in bacmid DNA enhances baculovirus genome stability and recombinant protein expression in insect cells
10.3390/v12121448 · 2020 · External reference
Protein N-glycosylation in the baculovirus-insect cell system
10.2174/138945007782151360 · 2007 · External reference
Protein-glycan interactions in the control of innate and adaptive immune responses
10.1038/ni.f.203 · 2008 · External reference
Enzyme-linked immunosorbent assay for serological diagnosis of chagas' disease employing a Trypanosoma cruzi recombinant antigen that consists of four different peptides
10.1128/jcm.39.12.4390-4395.2001 · 2001 · External reference
Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease—a phase II study
10.1371/journal.pntd.0005433 · 2017 · External reference
Rapid diagnostic tests and ELISA for diagnosing chronic chagas disease: systematic review and meta-analysis
10.1371/journal.pntd.0010860 · 2022 · External reference
Immune response to Trypanosoma cruzi shed acute phase antigen in children from an endemic area for chagas' disease in Bolivia
10.1590/s0074-02761997000400011 · 1997 · External reference
Autoimmunity in chronic chagas disease: a road of multiple pathways to cardiomyopathy?
10.3389/fimmu.2018.01842 · 2018 · External reference
Chagas disease cardiomyopathy: immunopathology and genetics
10.1155/2014/683230 · 2014 · External reference
