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References from Engineered bacteriophages for bacterial control and detection: From genome design to translation. Local targets link to admitted publications; unresolved targets remain external evidence.
Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing
10.1038/s41564-022-01258-x · 2022 · External reference
Clades of huge phages from across Earth’s ecosystems
10.1038/s41586-020-2007-4 · 2020 · External reference
Engineering modular viral scaffolds for targeted bacterial population editing
10.1016/j.cels.2015.08.013 · 2015 · External reference
Genome editing in bacteria: CRISPR-Cas and beyond
10.3390/microorganisms9040844 · 2021 · External reference
CRISPR–Cas therapies targeting bacteria
10.1038/s44222-025-00311-8 · 2025 · External reference
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
10.1038/nbt.3043 · 2014 · External reference
Predicting bacteriophage hosts based on sequences of annotated receptor-binding proteins
10.1038/s41598-021-81063-4 · 2021 · External reference
Phage-mediated horizontal gene transfer and its implications for the human gut microbiome
10.1093/gastro/goac012 · 2022 · External reference
Good manufacturing practice (GMP) compliance for phage therapy medicinal products
10.3389/fmicb.2020.01161 · 2020 · External reference
In situ targeted base editing of bacteria in the mouse gut
10.1038/s41586-024-07681-w · 2024 · External reference
Optimization of bacteriophage propagation in high-yield continuous culture (cellstat) meeting the constraints of industrial manufacturing processes
10.1016/j.jbiosc.2024.09.001 · 2024 · External reference
Mutation of a Staphylococcus aureus temperate bacteriophage to a virulent one and evaluation of its application
10.1016/j.fm.2019.03.025 · 2019 · External reference
A Klebsiella-phage cocktail to broaden the host range and delay bacteriophage resistance both in vitro and in vivo
10.1038/s41522-024-00603-8 · 2024 · External reference
Interactions between bacterial and phage communities in natural environments
10.1038/s41579-021-00602-y · 2022 · External reference
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
10.1038/nbt.3011 · 2014 · External reference
Re-evaluating what makes a phage unsuitable for therapy
10.1038/s44259-025-00117-z · 2025 · External reference
INfrastructure for a PHAge REference database: identification of large-scale biases in the current collection of cultured phage genomes
2021 · External reference
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
10.1073/pnas.120163297 · 2000 · External reference
Pseudomonas predators: understanding and exploiting phage–host interactions
10.1038/nrmicro.2017.61 · 2017 · External reference
Enhancing bacteriophage therapeutics through in situ production and release of heterologous antimicrobial effectors
10.1038/s41467-023-39612-0 · 2023 · External reference
Reprogramming bacteriophage host range: design principles and strategies for engineering receptor binding proteins
10.1016/j.copbio.2021.02.006 · 2021 · External reference
Reprogramming bacteriophage host range through structure-guided design of chimeric receptor binding proteins
10.1016/j.celrep.2019.09.062 · 2019 · External reference
Optimization of T4 phage engineering via CRISPR/Cas9
10.1038/s41598-020-75426-6 · 2020 · External reference
Unresolved reference
2023 · External reference
Unresolved reference
2025 · External reference
New applications for phage integrases
10.1016/j.jmb.2014.05.014 · 2014 · External reference
Thousands of small, novel genes predicted in global phage genomes
10.1016/j.celrep.2022.110984 · 2022 · External reference
Structural mechanism of bacteriophage lambda tail's interaction with the bacterial receptor
10.1038/s41467-024-48686-3 · 2024 · External reference
Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice
10.1038/s41587-023-01759-y · 2024 · External reference
Enzymatic assembly of DNA molecules up to several hundred kilobases
10.1038/nmeth.1318 · 2009 · External reference
Does phage-mediated horizontal gene transfer represent an environmental risk?
10.1016/j.tim.2022.07.011 · 2022 · External reference
HilE regulates HilD by blocking DNA binding in Salmonella enterica serovar Typhimurium
10.1128/jb.00750-17 · 2018 · External reference
GOPhage: protein function annotation for bacteriophages by integrating the genomic context
2025 · External reference
Big impact of the tiny: bacteriophage–bacteria interactions in biofilms
10.1016/j.tim.2019.04.006 · 2019 · External reference
Bacteriophages and their genomes
10.1016/j.coviro.2011.06.009 · 2011 · External reference
Filamentous phages: masters of a microbial sharing economy
10.15252/embr.201847427 · 2019 · External reference
Lysogeny in nature: mechanisms, impact and ecology of temperate phages
10.1038/ismej.2017.16 · 2017 · External reference
Stable neutralization of a virulence factor in bacteria using temperate phage in the mammalian gut
10.1128/msystems.00013-20 · 2020 · External reference
Phages for phage therapy: isolation, characterization, and host range breadth
10.3390/ph12010035 · 2019 · External reference
A synthetic biology approach to assemble and reboot clinically relevant Pseudomonas aeruginosa tailed phages
10.1128/spectrum.02897-23 · 2024 · External reference
A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity
10.1126/science.1225829 · 2012 · External reference
CRISPR/Cas9-Engineered Salmonella Phage Displaying Antimicrobial Peptide LL37 for Enhanced Antibacterial Activity
10.1016/j.ijantimicag.2026.107734 · 2026 · External reference
Development of CRISPR-Cas13a-based antimicrobials capable of sequence-specific killing of target bacteria
10.1038/s41467-020-16731-6 · 2020 · External reference
Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria
10.1073/pnas.1714658115 · 2018 · External reference
Elucidation of molecular function of phage protein responsible for optimization of host cell lysis
10.1186/s12866-024-03684-9 · 2024 · External reference
Sensitive detection of viable Escherichia coli O157:H7 from foods using a luciferase-reporter phage phiV10lux
10.1016/j.ijfoodmicro.2017.05.002 · 2017 · External reference
Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage
10.1016/j.micres.2025.128396 · 2026 · External reference
Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial
10.1016/s1473-3099(24)00424-9 · 2024 · External reference
Development of an engineered bioluminescent reporter phage for the sensitive detection of viable Salmonella Typhimurium
10.1021/ac500645c · 2014 · External reference
Efficient engineering of a bacteriophage genome using the type IE CRISPR-Cas system
10.4161/rna.27766 · 2014 · External reference
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
10.1016/j.celrep.2021.109930 · 2021 · External reference
Phage host range: determinants, dynamics and applications
10.1038/s41579-026-01306-x · 2026 · External reference
PHEIGES: all-cell-free phage synthesis and selection from engineered genomes
10.1038/s41467-024-46585-1 · 2024 · External reference
A modular view of the bacteriophage genomic space: identification of host and lifestyle marker modules
10.1016/j.resmic.2011.06.006 · 2011 · External reference
Phage-delivered sensitisation with subsequent antibiotic treatment reveals sustained effect against antimicrobial resistant bacteria
10.7150/thno.42573 · 2020 · External reference
Hydrogen peroxide-mediated induction of the Shiga toxin-converting lambdoid prophage ST2-8624 in Escherichia coli O157:H7
10.1111/j.1574-695x.2009.00644.x · 2010 · External reference
Dispersing biofilms with engineered enzymatic bacteriophage
10.1073/pnas.0704624104 · 2007 · External reference
Approaches for bacteriophage genome engineering
10.1016/j.tibtech.2022.08.008 · 2023 · External reference
Fluorescent reporter DS6A mycobacteriophages reveal unique variations in infectibility and phage production in mycobacteria
10.1128/jb.00592-16 · 2016 · External reference
Engineering therapeutic phages for enhanced antibacterial efficacy
10.1016/j.coviro.2021.12.003 · 2022 · External reference
Use of bacteriophage λ recombination functions to promote gene replacement in Escherichia coli
10.1128/jb.180.8.2063-2071.1998 · 1998 · External reference
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
10.1016/s0140-6736(21)02724-0 · 2022 · External reference
Robust approaches for the production of active ingredient and drug product for human phage therapy
10.3389/fmicb.2019.02289 · 2019 · External reference
Targeting mechanisms of tailed bacteriophages
10.1038/s41579-018-0070-8 · 2018 · External reference
Developing phage therapy that overcomes the evolution of bacterial resistance
10.1146/annurev-virology-012423-110530 · 2023 · External reference
Development of new strategy combining heat treatment and phage cocktail for post-contamination prevention
10.1016/j.foodres.2021.110415 · 2021 · External reference
An insight into phage diversity at environmental habitats using comparative metagenomics approach
10.1007/s00284-017-1357-0 · 2018 · External reference
Inhibition of biofilm formation by T7 bacteriophages producing quorum-quenching enzymes
10.1128/aem.01434-14 · 2014 · External reference
Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages
10.1073/pnas.1913234117 · 2020 · External reference
Safety, recovery, and pharmacodynamics of CRISPR–Cas therapeutic SNIPR001: a phase 1, randomised, double-blind, first-in-human, dose-escalation study
10.1016/j.lanmic.2025.101257 · 2026 · External reference
Improvement of pCVD442, a suicide plasmid for gene allele exchange in bacteria
10.1016/j.plasmid.2004.02.003 · 2004 · External reference
Genetically engineered phages: a review of advances over the last decade
10.1128/mmbr.00069-15 · 2016 · External reference
Functional ecology of bacteriophages in the environment
10.1016/j.mib.2022.102245 · 2023 · External reference
Next-generation sequencing technology: current trends and advancements
10.3390/biology12070997 · 2023 · External reference
Use of the lambda Red recombinase system to produce recombinant prophages carrying antibiotic resistance genes
10.1186/1471-2199-7-31 · 2006 · External reference
Impacts of food matrix on bacteriophage and endolysin antimicrobial efficacy and performance
10.1080/10408398.2019.1584874 · 2020 · External reference
Genome replication, synthesis, and assembly of the bacteriophage T7 in a single cell-free reaction
10.1021/sb300049p · 2012 · External reference
Phage therapy: From biological mechanisms to future directions
10.1016/j.cell.2022.11.017 · 2023 · External reference
Viruses in the sea
10.1038/nature04160 · 2005 · External reference
An effective antibiofilm strategy based on bacteriophages armed with silver nanoparticles
10.1038/s41598-024-59866-y · 2024 · External reference
Phage and endolysin therapy against antibiotics resistant bacteria: from bench to bedside
10.1002/mco2.70280 · 2025 · External reference
Experimental evolution of UV resistance in a phage
10.7717/peerj.5190 · 2018 · External reference
Phage-encoded bismuth bicycles enable instant access to targeted bioactive peptides
10.1038/s42004-024-01232-0 · 2024 · External reference
Bacteriophage replication modules
10.1111/j.1574-6976.2006.00015.x · 2006 · External reference
Homologous recombination and the repair of DNA double-strand breaks
10.1074/jbc.tm118.000372 · 2018 · External reference
Chelating agent shock of bacteriophage T5
10.1128/jvi.2.9.944-950.1968 · 1968 · External reference
Bacteriophage immunotherapy with artificial antigen-directed immune labeling against bacterial infection
10.1126/sciadv.adr1911 · 2025 · External reference
Engineering phage host-range and suppressing bacterial resistance through phage tail fiber mutagenesis
10.1016/j.cell.2019.09.015 · 2019 · External reference
Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria
10.1073/pnas.1500107112 · 2015 · External reference
Motley crew: overview of the currently available phage diversity
10.3389/fmicb.2020.579452 · 2020 · External reference
