Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Pre-splicing factors associate with UpA-rich RNA and limit flavivirus replication. Local targets link to admitted publications; unresolved targets remain external evidence.
Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
10.1126/science.aah3963 · 2016 · External reference
HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
10.1016/j.cell.2015.08.011 · 2015 · External reference
UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression
10.1038/mt.2012.29 · 2012 · External reference
Nucleoside modifications in RNA limit activation of 2’-5’-oligoadenylate synthetase and increase resistance to cleavage by RNase L
10.1093/nar/gkr586 · 2011 · External reference
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication
10.1093/nar/gku075 · 2014 · External reference
Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing
10.1016/j.molcel.2016.05.034 · 2016 · External reference
Structure of the activated human minor spliceosome
10.1126/science.abg0879 · 2021 · External reference
ARED-Plus: an updated and expanded database of AU-rich element-containing mRNAs and pre-mRNAs
10.1093/nar/gkx975 · 2018 · External reference
Evolution of the genome and the genetic code: selection at the dinucleotide level by methylation and polyribonucleotide cleavage
10.1073/pnas.86.1.192 · 1989 · External reference
U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing
10.1016/0092-8674(85)90270-3 · 1985 · External reference
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
2020 · External reference
The effect of increased CpG and UpA dinucleotides in the West Nile virus genome on virus transmission by Culex mosquitoes and pathogenesis in a vertebrate host
2025 · External reference
RNA Sequence Elements Required for High Affinity Binding by the Zinc Finger Domain of Tristetraprolin
10.1074/jbc.m402551200 · 2004 · External reference
Small Nuclear RNA
2013 · External reference
Over- and under-representation of short oligonucleotides in DNA sequences
10.1073/pnas.89.4.1358 · 1992 · External reference
Genetic Inactivation of Poliovirus Infectivity by Increasing the Frequencies of CpG and UpA Dinucleotides within and across Synonymous Capsid Region Codons
10.1128/jvi.00508-09 · 2009 · External reference
Decreased accumulation of subgenomic RNA in human cells infected with vaccine candidate DEN4Δ30 increases viral susceptibility to type I interferon
10.1016/j.vaccine.2018.04.087 · 2018 · External reference
Identification of RNA structures and their roles in RNA functions
2024 · External reference
The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production
10.1126/science.1250897 · 2014 · External reference
Functional Landscape of hnRNPA3 in Disease Pathogenesis
10.1002/wrna.70010 · 2025 · External reference
SYNCRIP, a Member of the Heterogeneous Nuclear Ribonucleoprotein Family, Is Involved in Mouse Hepatitis Virus RNA Synthesis
10.1128/jvi.78.23.13153-13162.2004 · 2004 · External reference
Origin of the OAS-RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering
10.1073/pnas.2304687120 · 2023 · External reference
IFIT1: A dual sensor and effector molecule that detects non-2′-O methylated viral RNA and inhibits its translation
10.1016/j.cytogfr.2014.05.002 · 2014 · External reference
Subgenomic flavivirus RNA as key target for live-attenuated vaccine development
10.1128/jvi.00100-23 · 2024 · External reference
Mammalian Mutation Pressure, Synonymous Codon Choice, and mRNA Degradation
10.1007/s00239-003-2519-1 · 2003 · External reference
Modulating splicing with small molecular inhibitors of the spliceosome
2016 · External reference
Nucleic‐acid‐binding properties of hnRNP‐U/SAF‐A, a nuclear‐matrix protein which binds DNA and RNA in vivo and in vitro
10.1111/j.1432-1033.1994.tb18788.x · 1994 · External reference
CpG and upA dinucleotides in both coding and non-coding regions of echovirus 7 inhibit replication initiation post-entry
10.7554/elife.29112 · 2017 · External reference
The dinucleotide composition of the Zika virus genome is shaped by conflicting evolutionary pressures in mammalian hosts and mosquito vectors
10.1371/journal.pbio.3001201 · 2021 · External reference
RNA Structures Required for Production of Subgenomic Flavivirus RNA
10.1128/jvi.01159-10 · 2010 · External reference
The hnRNP family: insights into their role in health and disease
2016 · External reference
Nearest-neighbor parameters for the prediction of RNA duplex stability in diverse in vitro and cellular-like crowding conditions
10.1093/nar/gkad020 · 2023 · External reference
Subgenomic flavivirus RNA binds the mosquito DEAD/H-box helicase ME31B and determines Zika virus transmission by Aedes aegypti
10.1073/pnas.1905617116 · 2019 · External reference
Post-transcriptional Regulatory Functions of Mammalian Pumilio Proteins
10.1016/j.tig.2018.09.006 · 2018 · External reference
Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production
10.1016/j.immuni.2024.02.002 · 2024 · External reference
Antigenic Characterization of New Lineage II Insect-Specific Flaviviruses in Australian Mosquitoes and Identification of Host Restriction Factors
10.1128/msphere.00095-20 · 2020 · External reference
Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
10.1016/j.molcel.2024.11.015 · 2024 · External reference
Dinucleotide relative abundance extremes: a genomic signature
10.1016/s0168-9525(00)89076-9 · 1995 · External reference
10.1016/s0168-9525(00)89076-9
10.1016/s0168-9525(00)89076-9 · External reference
Dinucleotide relative abundance extremes: a genomic signature
10.1016/s0168-9525(00)89076-9 · 1995 · External reference
Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A
10.1261/rna.071621.119 · 2019 · External reference
2’-5’-Oligoadenylate synthetase is activated by a specific RNA sequence motif
10.1016/j.bbrc.2009.07.167 · 2009 · External reference
Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation
10.1261/rna.1332609 · 2009 · External reference
An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
10.1093/nar/gkt956 · 2014 · External reference
hnRNPDL extensively regulates transcription and alternative splicing
10.1016/j.gene.2018.11.026 · 2019 · External reference
Research Progress on the Structural and Functional Roles of hnRNPs in Muscle Development
10.3390/biom13101434 · 2023 · External reference
A computational analysis of sequence features involved in recognition of short introns
10.1073/pnas.201407298 · 2001 · External reference
Alternate modes of cognate RNA recognition by human PUMILIO proteins
10.1016/j.str.2010.12.019 · 2011 · External reference
Cloning of human 2H9 heterogeneous nuclear ribonucleoproteins: Relation with splicing and early heat shock-induced splicing arrest
10.1074/jbc.272.3.1827 · 1997 · External reference
FUBP3: A new player in HIV-1 transcriptional activation and immune regulation
10.1016/j.omtn.2025.102565 · 2025 · External reference
Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing
10.1371/journal.pbio.0040021 · 2006 · External reference
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences
10.1073/pnas.1913232116 · 2019 · External reference
Differential regulation of the OASL and OAS1 genes in response to viral infections
10.1089/jir.2008.0050 · 2009 · External reference
Therapeutic Targeting of Alternative Splicing: A New Frontier in Cancer Treatment
10.3389/fonc.2022.868664 · 2022 · External reference
Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate
10.1099/jgv.0.000938 · 2017 · External reference
Strong doublet preferences in nucleotide sequences and DNA geometry
10.1007/bf02257371 · 1984 · External reference
The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides
10.1093/nar/gkz581 · 2019 · External reference
The PRIDE database at 20 years: 2025 update
10.1093/nar/gkae1011 · 2025 · External reference
A Highly Structured, Nuclease-Resistant, Noncoding RNA Produced by Flaviviruses Is Required for Pathogenicity
10.1016/j.chom.2008.10.007 · 2008 · External reference
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
10.1038/nprot.2007.261 · 2007 · External reference
Dinucleotide and stop codon frequencies in single-stranded RNA viruses
10.1099/0022-1317-78-11-2859 · 1997 · External reference
Noncoding subgenomic flavivirus RNA: Multiple functions in west Nile virus pathogenesis and modulation of host responses
10.3390/v6020404 · 2014 · External reference
Pick one, but be quick: 5′ splice sites and the problems of too many choices
10.1101/gad.209759.112 · 2013 · External reference
Who’s on first? The U1 snRNP-5 splice site interaction and splicing
10.1016/0968-0004(91)90073-5 · 1991 · External reference
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
10.1093/emboj/cdf639 · 2002 · External reference
Organellar maturases: A window into the evolution of the spliceosome
10.1016/j.bbabio.2015.01.009 · 2015 · External reference
Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla -selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses
10.1186/1471-2164-14-610 · 2013 · External reference
SSE: A nucleotide and amino acid sequence analysis platform
10.1186/1756-0500-5-50 · 2012 · External reference
The SF3b complex: splicing and beyond
10.1007/s00018-020-03493-z · 2020 · External reference
Vitro and in Vivo Evaluation of Mutations in the NS Region of Lineage 2 West Nile Virus Associated with Neuroinvasiveness in a Mammalian Model
10.3390/v8020049 · 2016 · External reference
CG dinucleotide suppression enables antiviral defence targeting non-self RNA
10.1038/nature24039 · 2017 · External reference
Selective forces and mutational biases drive stop codon usage in the human genome: A comparison with sense codon usage
10.1186/s12864-016-2692-4 · 2016 · External reference
RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies
10.7554/elife.04531 · 2014 · External reference
Effect of increased CpG and UpA dinucleotides in the West Nile virus genome on virus transmission by Culex mosquitoes and pathogenesis in a vertebrate host
10.1128/jvi.01102-25 · 2025 · External reference
Human pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs
10.1074/jbc.m112.373522 · 2012 · External reference
Nuclear Matrix Factor hnRNP U/SAF-A Exerts a Global Control of Alternative Splicing by Regulating U2 snRNP Maturation
10.1016/j.molcel.2012.01.009 · 2012 · External reference
Versatile Role for hnRNP D Isoforms in the Differential Regulation of Cytoplasmic mRNA Turnover
10.1128/mcb.21.20.6960-6971.2001 · 2001 · External reference
Short Direct Repeats in the 3’ Untranslated Region Are Involved in Subgenomic Flaviviral RNA Production
10.1128/jvi.01175-19 · 2020 · External reference
Structural insights into how Prp5 proofreads the pre-mRNA branch site
10.1038/s41586-021-03789-5 · 2021 · External reference
SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis
10.1016/j.molcel.2023.11.032 · 2024 · External reference
Serine-arginine protein kinases and their targets in viral infection and their inhibition
10.1007/s00018-023-04808-6 · 2023 · External reference
COMRADES determines in vivo RNA structures and interactions
10.1038/s41592-018-0121-0 · 2018 · External reference
