Research graph
References from Immune–vascular–fibrotic remodeling defines a neuroimmune tissue niche in systemic sclerosis skin and converges with human peripheral nerve injury programs. Local targets link to admitted publications; unresolved targets remain external evidence.
Systemic sclerosis
2015 · External reference
Epidemiology and treatment of peripheral neuropathy in systemic sclerosis
10.3899/jrheum.201299 · 2021 · External reference
Evaluating the associations among dysautonomia, gastrointestinal transit, and clinical phenotype in patients with systemic sclerosis
10.1002/acr.25411 · 2024 · External reference
Nervous system involvement in systemic sclerosis
10.1016/j.semarthrit.2013.05.002 · 2013 · External reference
Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis
10.1002/art.39289 · 2015 · External reference
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures
10.1136/annrheumdis-2019-215770 · 2019 · External reference
Minimum information about a microarray experiment (MIAME) toward standards for microarray data
10.1038/ng1201-365 · 2001 · External reference
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis: the TRIPOD statement
10.7326/m14-0697 · 2015 · External reference
Heart rate variability helps classify phenotype in systemic sclerosis
10.1038/s41598-024-60553-1 · 2024 · External reference
Systemic sclerosis
10.1016/s0140-6736(17)30933-9 · 2017 · External reference
Neuroinflammation and the generation of neuropathic pain
10.1093/bja/aet128 · 2013 · External reference
Immune cell dysregulation as a mediator of fibrosis in systemic sclerosis
10.1038/s41584-022-00864-7 · 2022 · External reference
Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?
10.1186/s13075-021-02633-5 · 2021 · External reference
Regularization paths for generalized linear models via coordinate descent
10.18637/jss.v033.i01 · 2010 · External reference
Scleroderma
10.1056/nejmra0806188 · 2009 · External reference
Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis
10.1136/annrheumdis-2021-220209 · 2021 · External reference
LGR5 expressing skin fibroblasts define a major cellular hub perturbed in systemic sclerosis
10.1016/j.cell.2022.03.011 · 2022 · External reference
GSVA: gene set variation analysis for microarray and RNA-seq data
10.1186/1471-2105-14-7 · 2013 · External reference
Autonomic dysfunction in systemic sclerosis: a scoping review
2023 · External reference
Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
10.1038/s41467-021-26099-w · 2021 · External reference
WGCNA: an R package for weighted correlation network analysis
10.1186/1471-2105-9-559 · 2008 · External reference
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
10.1186/gb-2014-15-2-r29 · 2014 · External reference
Classification and regression by randomForest
2002 · External reference
An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury
10.1186/s12974-022-02462-6 · 2022 · External reference
Neuroinflammation in the peripheral nerve: cause, modulator, or bystander in peripheral neuropathies?
10.1002/glia.22899 · 2016 · External reference
Unresolved reference
External reference
Large fiber peripheral neuropathy in systemic sclerosis: a prospective study using clinical and electrophysiological definition
10.1111/1756-185x.14042 · 2021 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
pROC: an open-source package for R and S+ to analyze and compare ROC curves
10.1186/1471-2105-12-77 · 2011 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
Sympatho-vagal dysfunction in systemic sclerosis: a follow-up study
10.3390/life13010034 · 2022 · External reference
The systolic pulmonary arterial pressure liaises impaired cardiac autonomic control to pro-inflammatory status in systemic sclerosis patients
10.3389/fcvm.2022.899290 · 2022 · External reference
Comprehensive integration of single-cell data
10.1016/j.cell.2019.05.031 · 2019 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin
10.1038/s41467-021-24607-6 · 2021 · External reference
Systemic sclerosis: a prototypic multisystem fibrotic disorder
10.1172/jci31139 · 2007 · External reference
The Strengthening the Reporting of Observational Studies in Epidemiology statement: guidelines for reporting observational studies
10.1371/journal.pmed.0040296 · 2007 · External reference
Neuroimmune interactions and immunoengineering strategies in peripheral nerve repair
10.1016/j.pneurobio.2021.102172 · 2022 · External reference
Disentangling glial diversity in peripheral nerves at single-nuclei resolution
10.1038/s41593-021-01005-1 · 2022 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
Evaluating the associations among dysautonomia, gastrointestinal transit, and clinical phenotype in patients with systemic sclerosis
10.1002/acr.25411 · ExternalCitation · doi-reference
Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis
10.1002/art.39289 · ExternalCitation · doi-reference
Neuroinflammation in the peripheral nerve: cause, modulator, or bystander in peripheral neuropathies?
10.1002/glia.22899 · ExternalCitation · doi-reference
Comprehensive integration of single-cell data
10.1016/j.cell.2019.05.031 · ExternalCitation · doi-reference
LGR5 expressing skin fibroblasts define a major cellular hub perturbed in systemic sclerosis
10.1016/j.cell.2022.03.011 · ExternalCitation · doi-reference
Neuroimmune interactions and immunoengineering strategies in peripheral nerve repair
10.1016/j.pneurobio.2021.102172 · ExternalCitation · doi-reference
Nervous system involvement in systemic sclerosis
10.1016/j.semarthrit.2013.05.002 · ExternalCitation · doi-reference
Systemic sclerosis
10.1016/s0140-6736(17)30933-9 · ExternalCitation · doi-reference
Minimum information about a microarray experiment (MIAME) toward standards for microarray data
10.1038/ng1201-365 · ExternalCitation · doi-reference
Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin
10.1038/s41467-021-24607-6 · ExternalCitation · doi-reference
Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
10.1038/s41467-021-26099-w · ExternalCitation · doi-reference
Immune cell dysregulation as a mediator of fibrosis in systemic sclerosis
10.1038/s41584-022-00864-7 · ExternalCitation · doi-reference
Disentangling glial diversity in peripheral nerves at single-nuclei resolution
10.1038/s41593-021-01005-1 · ExternalCitation · doi-reference
Heart rate variability helps classify phenotype in systemic sclerosis
10.1038/s41598-024-60553-1 · ExternalCitation · doi-reference
Scleroderma
10.1056/nejmra0806188 · ExternalCitation · doi-reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · ExternalCitation · doi-reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · ExternalCitation · doi-reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · ExternalCitation · doi-reference
Neuroinflammation and the generation of neuropathic pain
10.1093/bja/aet128 · ExternalCitation · doi-reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · ExternalCitation · doi-reference
Large fiber peripheral neuropathy in systemic sclerosis: a prospective study using clinical and electrophysiological definition
10.1111/1756-185x.14042 · ExternalCitation · doi-reference
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures
10.1136/annrheumdis-2019-215770 · ExternalCitation · doi-reference
Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis
10.1136/annrheumdis-2021-220209 · ExternalCitation · doi-reference
Systemic sclerosis: a prototypic multisystem fibrotic disorder
10.1172/jci31139 · ExternalCitation · doi-reference
pROC: an open-source package for R and S+ to analyze and compare ROC curves
10.1186/1471-2105-12-77 · ExternalCitation · doi-reference
GSVA: gene set variation analysis for microarray and RNA-seq data
10.1186/1471-2105-14-7 · ExternalCitation · doi-reference
WGCNA: an R package for weighted correlation network analysis
10.1186/1471-2105-9-559 · ExternalCitation · doi-reference
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
10.1186/gb-2014-15-2-r29 · ExternalCitation · doi-reference
An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury
10.1186/s12974-022-02462-6 · ExternalCitation · doi-reference
Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?
10.1186/s13075-021-02633-5 · ExternalCitation · doi-reference
The Strengthening the Reporting of Observational Studies in Epidemiology statement: guidelines for reporting observational studies
10.1371/journal.pmed.0040296 · ExternalCitation · doi-reference
Regularization paths for generalized linear models via coordinate descent
10.18637/jss.v033.i01 · ExternalCitation · doi-reference
The systolic pulmonary arterial pressure liaises impaired cardiac autonomic control to pro-inflammatory status in systemic sclerosis patients
10.3389/fcvm.2022.899290 · ExternalCitation · doi-reference
Sympatho-vagal dysfunction in systemic sclerosis: a follow-up study
10.3390/life13010034 · ExternalCitation · doi-reference
Epidemiology and treatment of peripheral neuropathy in systemic sclerosis
10.3899/jrheum.201299 · ExternalCitation · doi-reference
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis: the TRIPOD statement
10.7326/m14-0697 · ExternalCitation · doi-reference
