Research graph
References from Biohybrid nanovesicle-mediated targeted delivery of HSP90 inhibitor for enhanced sorafenib therapy of hepatocellular carcinoma after radiofrequency ablation. Local targets link to admitted publications; unresolved targets remain external evidence.
Liver cancer in 2021: Global Burden of Disease study
10.1016/j.jhep.2024.10.031 · 2025 · External reference
Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment
10.3350/cmh.2024.0824 · 2025 · External reference
Epidemiology of hepatocellular carcinoma
10.1002/hep.31288 · 2021 · External reference
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2024 · External reference
Human liver cancer organoids: biological applications, current challenges, and prospects in hepatoma therapy
10.1016/j.canlet.2022.216048 · 2023 · External reference
Surgical treatments of hepatobiliary cancers
10.1002/hep.31325 · 2021 · External reference
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells
10.1038/s41423-020-00572-w · 2021 · External reference
Clinical guidelines for early hepatocellular carcinoma treatment options: a systematic review and bibliometric analysis
10.1097/js9.0000000000001950 · 2024 · External reference
Radiofrequency ablation: mechanisms and clinical applications
10.1002/mco2.746 · 2024 · External reference
Immunotherapies for hepatocellular carcinoma
10.1038/s41571-021-00573-2 · 2022 · External reference
The mechanisms of sorafenib resistance in hepatocellular carcinoma: theoretical basis and therapeutic aspects
10.1038/s41392-020-0187-x · 2020 · External reference
Mechanisms of drug resistance in HCC
10.1097/hep.0000000000000237 · 2024 · External reference
Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation
10.1038/s41388-018-0169-4 · 2018 · External reference
Glycosylation-related molecular subtypes and risk score of hepatocellular carcinoma: novel insights to clinical decision-making
10.3389/fendo.2022.1090324 · 2022 · External reference
Ubiquitin specific peptidase 3: an emerging deubiquitinase that regulates physiology and diseases
10.1038/s41420-024-02010-6 · 2024 · External reference
Sorafenib as adjuvant therapy following radiofrequency ablation for recurrent hepatocellular carcinoma within Milan criteria: a multicenter analysis
10.1007/s00535-022-01895-3 · 2022 · External reference
Therapy resistance mediated by cancer stem cells
10.1016/j.semcancer.2018.11.006 · 2018 · External reference
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
10.1038/nrclinonc.2015.61 · 2015 · External reference
Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update
10.1038/s41571-019-0293-2 · 2020 · External reference
Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice
10.1016/j.addr.2008.08.007 · 2009 · External reference
Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells
10.1038/s41467-020-18954-z · 2020 · External reference
Structural and functional complexity of HSP90 in cellular homeostasis and disease
10.1038/s41580-023-00640-9 · 2023 · External reference
The inhibitor of differentiation isoform Id1b, generated by alternative splicing, maintains cell quiescence and confers self-renewal and cancer stem cell-like properties
10.1016/j.canlet.2014.10.035 · 2015 · External reference
Targeting the mechano-microenvironment and liver cancer stem cells: a promising therapeutic strategy for liver cancer
2023 · External reference
Structural and functional complexity of HSP90 in cellular homeostasis and disease
10.1038/s41580-023-00640-9 · 2023 · External reference
Acidosis acts through HSP90 in a PHD/VHL-Independent manner to promote HIF function and stem cell maintenance in Glioma
10.1158/0008-5472.can-15-2630 · 2016 · External reference
HSP90 facilitates stemness and enhances glycolysis in glioma cells
10.1186/s12883-022-02924-7 · 2022 · External reference
Hsp90 promotes gastric cancer cell metastasis and stemness by regulating the regional distribution of glycolysis-related metabolic enzymes in the cytoplasm
2024 · External reference
Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: overview and current state of the art
10.1016/j.biopha.2018.03.102 · 2018 · External reference
Preclinical data on efficacy of 10 drug-radiation combinations: evaluations, concerns, and recommendations
10.1016/j.tranon.2016.01.002 · 2016 · External reference
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation
10.1158/0008-5472.can-13-1641 · 2014 · External reference
Resistance to cell death and its modulation in cancer stem cells
10.1615/critrevoncog.2016016976 · 2016 · External reference
Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry
10.1038/nprot.2007.405 · 2007 · External reference
Nanomedicine in cancer therapy
10.1038/s41392-023-01536-y · 2023 · External reference
Milk-derived exosomes as functional nanocarriers in wound healing: mechanisms, applications, and future directions
2025 · External reference
Oral TNF-α siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease
2024 · External reference
PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma
10.1186/s13046-024-03061-4 · 2024 · External reference
A NIR-II AIEgen-Based supramolecular nanodot for peroxynitrite-potentiated mild-temperature photothermal therapy of hepatocellular carcinoma
10.1002/adfm.202213134 · 2023 · External reference
A pH-Sensitive nanosized covalent-organic polymer for enhanced tumor photodynamic immunotherapy by hypoxia relief and STAT3 inhibition
2025 · External reference
Simultaneous inhibition of heat shock proteins and autophagy enhances radiofrequency ablation of hepatocellular carcinoma
10.1039/d4bm01190b · 2024 · External reference
