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References from Biomimetic nanoparticles camouflaged with M2 macrophage membrane for osteoporosis therapy: A triple-action strategy that upregulates anti-inflammation and osteogenic responses while suppressing MMP-9. Local targets link to admitted publications; unresolved targets remain external evidence.
Osteoporosis
10.1016/s0140-6736(25)01385-6 · 2025 · External reference
The path to healthy ageing in China: a peking university-lancet commission
10.1016/s0140-6736(22)01546-x · 2022 · External reference
Glucocorticoid-induced osteoporosis: novel concepts and clinical implications
10.1016/s2213-8587(25)00251-7 · 2025 · External reference
The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the global burden of disease study 2021
10.1016/s2665-9913(25)00105-5 · 2025 · External reference
Long-term and sequential treatment for osteoporosis
10.1038/s41574-023-00866-9 · 2023 · External reference
Influences of aged bone marrow macrophages on skeletal health and senescence
10.1007/s11914-023-00820-8 · 2023 · External reference
Senescent immune cells release grancalcin to promote skeletal aging
10.1016/j.cmet.2021.08.009 · 2021 · External reference
The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
10.1038/s42255-024-01187-5 · 2025 · External reference
Deletion or inhibition of the oxygen sensor PHD1 protects against ischemic stroke via reprogramming of neuronal metabolism
10.1016/j.cmet.2015.12.007 · 2016 · External reference
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics
10.1016/j.biomaterials.2026.124115 · 2026 · External reference
Pharmacological targeting of nuclear factor (erythroid-derived 2)-like 2 (NRF2): a potential strategy to improve the efficacy of oncological photodynamic therapy
2025 · External reference
Bergapten-loaded multifunctional soluble microneedle patch with bidirectional ROS regulation and pyroptosis suppression accelerates chronic infected wound healing via the Nrf2-NF-κB-NLRP3 axis
2026 · External reference
The significance of precisely regulating heme oxygenase-1 expression: another avenue for treating age-related ocular disease?
10.1016/j.arr.2024.102308 · 2024 · External reference
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy
10.1038/s41392-026-02598-4 · 2026 · External reference
Carnosine-modified gelatin-hyaluronic acid hydrogel comprising fenofibrate-loaded nanoparticles targeting chondrocyte ferroptosis and macrophage polarization for synergistic osteoarthritis therapy
2026 · External reference
Metal-polyphenol network coated bilirubin nanoparticles for the alleviation of periodontitis via mild photothermal therapy and immunomodulatory therapy
10.1021/acsnano.5c05266 · 2025 · External reference
Osmotin-derived 9-amino-acid peptide alleviates α-synuclein and MPTP-induced glial cell activation mediated neuroinflammation, protecting dopaminergic neurons in Parkinson's disease mice brain
10.1186/s12929-026-01215-4 · 2026 · External reference
IkappaB-NF-kappaB structures: at the interface of inflammation control
10.1016/s0092-8674(00)81694-3 · 1998 · External reference
The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80
10.1093/nar/gkz873 · 2019 · External reference
An aggrecanase-responsive delivery hydrogel system of miRNA-17 facilitates microfracture-mediated articular cartilage regeneration by reprogramming hostile inflammatory niche
10.1021/acsnano.4c16049 · 2025 · External reference
Matrix Metalloproteinase-9 enhances osteoclastogenesis: insights from transgenic rabbit bone marrow models and in vitro studies
10.3390/ijms26073194 · 2025 · External reference
Transcriptomics guided engineering of exosome-encapsulated bifunctional nanosheets targeting the Immune-PI3K/Akt axis for osteoporosis therapy
2025 · External reference
Postmenopausal osteoporosis
10.1056/nejmcp2307353 · 2023 · External reference
Engineering of metal-organic networks as band-aid for the repair of osteoporotic bone fractures
10.1021/acsnano.5c15619 · 2025 · External reference
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration
10.1016/j.biomaterials.2023.122266 · 2023 · External reference
Piezo1 activation suppresses bone marrow adipogenesis to prevent osteoporosis by inhibiting a mechanoinflammatory autocrine loop
10.1038/s41392-025-02455-w · 2025 · External reference
Bone-targeted delivery of Cell-Penetrating-RUNX2 fusion protein in osteoporosis model
2023 · External reference
RUNX2 phase separation mediates long-range regulation between osteoporosis-susceptibility variant and XCR1 to promote osteoblast differentiation
2025 · External reference
Triple-functional bone adhesive with enhanced internal fixation, bacteriostasis and osteoinductive properties for open fracture repair
2023 · External reference
Klotho in Osx(+)-mesenchymal progenitors exerts pro-osteogenic and anti-inflammatory effects during mandibular alveolar bone formation and repair
10.1038/s41392-022-00957-5 · 2022 · External reference
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3
10.1080/15548627.2020.1839286 · 2021 · External reference
Premature aging of skeletal stem/progenitor cells rather than osteoblasts causes bone loss with decreased mechanosensation
10.1038/s41413-023-00269-6 · 2023 · External reference
Fam102a translocates Runx2 and Rbpjl to facilitate osterix expression and bone formation
10.1038/s41467-024-55451-z · 2025 · External reference
Nanomedicine tumor targeting
10.1002/adma.202312169 · 2024 · External reference
Bone targeted nano-drug and nano-delivery
10.1038/s41413-024-00356-2 · 2024 · External reference
Immune-regulating camouflaged nanoplatforms: a promising strategy to improve cancer nano-immunotherapy
2023 · External reference
Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment
10.1016/j.canlet.2023.216397 · 2023 · External reference
Biomimetic macrophage membrane-camouflaged nanoparticles induce ferroptosis by promoting mitochondrial damage in glioblastoma
10.1021/acsnano.3c07555 · 2023 · External reference
Astragalus polysaccharide hydrogels with drug-carrying super self-assembly from natural herbs promote wound healing
10.1021/acsnano.5c03744 · 2025 · External reference
Oral microsphere formulation of M2 macrophage-mimetic Janus nanomotor for targeted therapy of ulcerative colitis
10.1126/sciadv.ado6798 · 2024 · External reference
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage
10.1016/j.biomaterials.2023.122036 · 2023 · External reference
M2 macrophage hybrid membrane-camouflaged targeted biomimetic nanosomes to reprogram inflammatory microenvironment for enhanced enzyme-thermo-immunotherapy
10.1002/adma.202304123 · 2023 · External reference
M2 macrophage hybrid membrane-camouflaged targeted biomimetic nanosomes to reprogram inflammatory microenvironment for enhanced enzyme-thermo-immunotherapy
10.1002/adma.202304123 · ExternalCitation · doi-reference
Nanomedicine tumor targeting
10.1002/adma.202312169 · ExternalCitation · doi-reference
Influences of aged bone marrow macrophages on skeletal health and senescence
10.1007/s11914-023-00820-8 · ExternalCitation · doi-reference
The significance of precisely regulating heme oxygenase-1 expression: another avenue for treating age-related ocular disease?
10.1016/j.arr.2024.102308 · ExternalCitation · doi-reference
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage
10.1016/j.biomaterials.2023.122036 · ExternalCitation · doi-reference
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration
10.1016/j.biomaterials.2023.122266 · ExternalCitation · doi-reference
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics
10.1016/j.biomaterials.2026.124115 · ExternalCitation · doi-reference
Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment
10.1016/j.canlet.2023.216397 · ExternalCitation · doi-reference
Deletion or inhibition of the oxygen sensor PHD1 protects against ischemic stroke via reprogramming of neuronal metabolism
10.1016/j.cmet.2015.12.007 · ExternalCitation · doi-reference
Senescent immune cells release grancalcin to promote skeletal aging
10.1016/j.cmet.2021.08.009 · ExternalCitation · doi-reference
IkappaB-NF-kappaB structures: at the interface of inflammation control
10.1016/s0092-8674(00)81694-3 · ExternalCitation · doi-reference
The path to healthy ageing in China: a peking university-lancet commission
10.1016/s0140-6736(22)01546-x · ExternalCitation · doi-reference
Osteoporosis
10.1016/s0140-6736(25)01385-6 · ExternalCitation · doi-reference
Glucocorticoid-induced osteoporosis: novel concepts and clinical implications
10.1016/s2213-8587(25)00251-7 · ExternalCitation · doi-reference
The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the global burden of disease study 2021
10.1016/s2665-9913(25)00105-5 · ExternalCitation · doi-reference
Biomimetic macrophage membrane-camouflaged nanoparticles induce ferroptosis by promoting mitochondrial damage in glioblastoma
10.1021/acsnano.3c07555 · ExternalCitation · doi-reference
An aggrecanase-responsive delivery hydrogel system of miRNA-17 facilitates microfracture-mediated articular cartilage regeneration by reprogramming hostile inflammatory niche
10.1021/acsnano.4c16049 · ExternalCitation · doi-reference
Astragalus polysaccharide hydrogels with drug-carrying super self-assembly from natural herbs promote wound healing
10.1021/acsnano.5c03744 · ExternalCitation · doi-reference
Metal-polyphenol network coated bilirubin nanoparticles for the alleviation of periodontitis via mild photothermal therapy and immunomodulatory therapy
10.1021/acsnano.5c05266 · ExternalCitation · doi-reference
Engineering of metal-organic networks as band-aid for the repair of osteoporotic bone fractures
10.1021/acsnano.5c15619 · ExternalCitation · doi-reference
Klotho in Osx(+)-mesenchymal progenitors exerts pro-osteogenic and anti-inflammatory effects during mandibular alveolar bone formation and repair
10.1038/s41392-022-00957-5 · ExternalCitation · doi-reference
Piezo1 activation suppresses bone marrow adipogenesis to prevent osteoporosis by inhibiting a mechanoinflammatory autocrine loop
10.1038/s41392-025-02455-w · ExternalCitation · doi-reference
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy
10.1038/s41392-026-02598-4 · ExternalCitation · doi-reference
Premature aging of skeletal stem/progenitor cells rather than osteoblasts causes bone loss with decreased mechanosensation
10.1038/s41413-023-00269-6 · ExternalCitation · doi-reference
Bone targeted nano-drug and nano-delivery
10.1038/s41413-024-00356-2 · ExternalCitation · doi-reference
Fam102a translocates Runx2 and Rbpjl to facilitate osterix expression and bone formation
10.1038/s41467-024-55451-z · ExternalCitation · doi-reference
Long-term and sequential treatment for osteoporosis
10.1038/s41574-023-00866-9 · ExternalCitation · doi-reference
The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
10.1038/s42255-024-01187-5 · ExternalCitation · doi-reference
Postmenopausal osteoporosis
10.1056/nejmcp2307353 · ExternalCitation · doi-reference
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3
10.1080/15548627.2020.1839286 · ExternalCitation · doi-reference
The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80
10.1093/nar/gkz873 · ExternalCitation · doi-reference
Oral microsphere formulation of M2 macrophage-mimetic Janus nanomotor for targeted therapy of ulcerative colitis
10.1126/sciadv.ado6798 · ExternalCitation · doi-reference
Osmotin-derived 9-amino-acid peptide alleviates α-synuclein and MPTP-induced glial cell activation mediated neuroinflammation, protecting dopaminergic neurons in Parkinson's disease mice brain
10.1186/s12929-026-01215-4 · ExternalCitation · doi-reference
Matrix Metalloproteinase-9 enhances osteoclastogenesis: insights from transgenic rabbit bone marrow models and in vitro studies
10.3390/ijms26073194 · ExternalCitation · doi-reference
