Research graph
References from Mitochondria targeted cancer therapy using ethidium derivatives. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2017
10.3322/caac.21387 · 2017 · External reference
Global cancer transitions according to the human development index (2008–2030): a population-based study
10.1016/s1470-2045(12)70211-5 · 2012 · External reference
Cancer treatment and survivorship statistics
10.3322/caac.21235 · 2014 · External reference
Tumour-targeted nanomedicines: principles and practice
10.1038/sj.bjc.6604483 · 2008 · External reference
Ligand-targeted therapeutics in anticancer therapy
10.1038/nrc903 · 2002 · External reference
Antibody targeted drugs as cancer therapeutics
10.1038/nrd1957 · 2006 · External reference
Drug penetration in solid tumours
10.1038/nrc1893 · 2006 · External reference
Subcellular targeting strategies for drug design and delivery
10.1038/nrd2897 · 2010 · External reference
Mitochondria-targeted aggregation induced emission theranostics: crucial importance of in situ activation
10.1039/c6sc02236g · 2016 · External reference
Integrating enzymatic self-assembly and mitochondria targeting for selectively killing cancer cells without acquired drug resistance
10.1021/jacs.6b09783 · 2016 · External reference
Mitochondria-targeted cancer therapy using a light-up probe with aggregation-induced-emission characteristics
10.1002/anie.201408897 · 2014 · External reference
Organometallic rhenium complexes divert doxorubicin to the mitochondria
10.1002/anie.201511432 · 2016 · External reference
Mitochondria, oxidative stress and cell death
10.1007/s10495-007-0756-2 · 2007 · External reference
Mitochondrial function in normal and diabetic β-cells
10.1038/414807a · 2001 · External reference
Mitochondrial biology, targets, and drug delivery
10.1016/j.jconrel.2015.03.036 · 2015 · External reference
Mitochondria-targeted chimeric peptide for trinitarian overcoming of drug resistance
10.1021/acsami.6b06522 · 2016 · External reference
Chemotherapy: targeting the mitochondrial cell death pathway
10.1038/sj.onc.1206039 · 2002 · External reference
Dual-stage-light-guided tumor inhibition by mitochondria-targeted photodynamic therapy
10.1002/adfm.201500590 · 2015 · External reference
Reconsidering azobenzene as a component of small-molecule hypoxia-mediated cancer drugs: a theranostic case study
10.1016/j.biomaterials.2016.11.023 · 2017 · External reference
Targeting mitochondria for cancer therapy
10.1038/nrd3137 · 2010 · External reference
Targeting mitochondria metabolism for cancer therapy
10.1038/nchembio.1712 · 2015 · External reference
Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics
10.1073/pnas.1210096109 · 2012 · External reference
Organelle-targeted nanocarriers: specific delivery of liposomal ceramide to mitochondria enhances its cytotoxicity in vitro and in vivo
10.1021/nl801908y · 2008 · External reference
Mechanism-guided design and synthesis of a mitochondria-targeting artemisinin analogue with enhanced anticancer activity
10.1002/anie.201607303 · 2016 · External reference
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore
10.1021/ja2077922 · 2012 · External reference
An activatable theranostic for targeted cancer therapy and imaging
10.1002/anie.201311133 · 2014 · External reference
Gemcitabine-coumarin-biotin conjugates: a target specific theranostic anticancer prodrug
10.1021/ja401350x · 2013 · External reference
Targeted theranostic platinum (IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ
10.1021/ja411811w · 2014 · External reference
Liposomal texaphyrin theranostics for metastatic liver cancer
10.1021/jacs.6b09713 · 2016 · External reference
Direct fluorescence monitoring of the delivery and cellular uptake of a cancer-targeted RGD peptide-appended naphthalimide theragnostic prodrug
10.1021/ja303998y · 2012 · External reference
Disulfide-based multifunctional conjugates for targeted theranostic drug delivery
10.1021/acs.accounts.5b00406 · 2015 · External reference
Design and synthesis of fluorescent probes for selective detection of highly reactive oxygen species in mitochondria of living cells
10.1021/ja073220m · 2007 · External reference
Novel fluorinated docetaxel analog for anti-hepatoma: molecular docking and biological evaluation
10.1016/j.ejpb.2013.06.008 · 2013 · External reference
Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting
10.3109/1061186x.2010.536983 · 2011 · External reference
Complex formation between EB and nucleic acids
10.1016/s0022-2836(65)80096-1 · 1965 · External reference
Mechanism of EB fluorescence enhancement on binding to nucleic acids
10.1021/bi00635a022 · 1977 · External reference
A fluorescent complex between EB and nucleic acids: physical-chemical characterization
10.1016/0022-2836(67)90353-1 · 1967 · External reference
Basis for the selective cytotoxicity of rhodamine 123
1987 · External reference
Increased rhodamine 123 uptake by carcinoma cells
1985 · External reference
Mitochondrial induced and self-monitored intrinsic apoptosis by antitumor theranostic prodrug: in vivo imaging and precise cancer treatment
10.1021/ja510421q · 2014 · External reference
Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation
10.1073/pnas.84.15.5444 · 1987 · External reference
Delocalized lipophilic cations selectively target the mitochondria of carcinoma cell
10.1016/s0169-409x(01)00125-9 · 2001 · External reference
Synthesis, photophysical properties, and nucleic acid binding of phenanthridinium derivatives based on ethidium
10.1016/j.bmc.2003.08.006 · 2003 · External reference
Experimental studies on the antitumor effect of EB and related substances
1974 · External reference
Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity
10.1021/jm9702692 · 1997 · External reference
A surface charge-switchable and folate modified system for co-delivery of proapoptosis peptide and p53 plasmid in cancer therapy
10.1016/j.biomaterials.2015.11.013 · 2016 · External reference
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
10.1073/pnas.88.9.3671 · 1991 · External reference
A porphyrin photosensitized metal-organic framework for cancer cell apoptosis and caspase responsive theranostics
10.1039/c5cc03028e · 2015 · External reference
Reactive oxygen species in mitochondria-mediated cell death
10.1080/03602530701468516 · 2007 · External reference
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
10.1152/ajpcell.00139.2004 · 2004 · External reference
Role of reactive oxygen species (ROS) in apoptosis induction
10.1023/a:1009616228304 · 2000 · External reference
How mitochondria produce reactive oxygen species
10.1042/bj20081386 · 2009 · External reference
Mitochondria: a hub of redox activities and cellular distress control
10.1007/s11010-007-9520-8 · 2007 · External reference
Classification of mitocans, anti-cancer drugs acting on mitochondria
10.1016/j.mito.2012.07.112 · 2013 · External reference
Cancer chemoprevention and mitochondria: targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state
10.1002/mnfr.200700527 · 2009 · External reference
Mitochondria, oxidants, and aging
10.1016/j.cell.2005.02.001 · 2005 · External reference
Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death
10.1038/ncomms7907 · 2015 · External reference
Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium (iii) complexes
10.1039/c6sc02901a · 2017 · External reference
Mitochondrial metabolism and ROS generation are essential for kras-mediated tumorigenicity
10.1073/pnas.1003428107 · 2010 · External reference
The ATP synthase is involved in generating mitochondrial cristae morphology
10.1093/emboj/21.3.221 · 2002 · External reference
Mechanisms of cytochrome C release from mitochondria
10.1038/sj.cdd.4401950 · 2006 · External reference
Mitochondria and apoptosis
10.1126/science.281.5381.1309 · 1998 · External reference
Mitochondria: releasing power for life and unleashing the machineries of death
10.1016/s0092-8674(03)00116-8 · 2003 · External reference
Targeting cancer metabolism: a therapeutic window opens
10.1038/nrd3504 · 2011 · External reference
