Research graph
References from Nano-catalytic carbon dot disrupts hypoxia-driven cascade reaction and ameliorates temozolomide-mediated glioblastoma suppression. Local targets link to admitted publications; unresolved targets remain external evidence.
New insights into targeted therapy of glioblastoma using smart nanoparticles
10.1186/s12935-024-03331-3 · 2024 · External reference
Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma
10.1038/s41467-022-31799-y · 2022 · External reference
Molecular targets and nanoparticulate systems designed for the improved therapeutic intervention in glioblastoma multiforme
10.1055/a-1296-7870 · 2021 · External reference
Frontiers in the treatment of glioblastoma: past, present and emerging
10.1016/j.addr.2021.01.012 · 2021 · External reference
Management of Glioblastoma: state of the art and future directions
2020 · External reference
Epidemiology and Etiology of Glioblastoma
2021 · External reference
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
10.1038/nature07385 · 2008 · External reference
Research progress of drug resistance mechanism of temozolomide in the treatment of glioblastoma
10.1016/j.heliyon.2024.e39984 · 2024 · External reference
Change of oxygen pressure in glioblastoma tissue under various conditions
10.1023/a:1015832726054 · 2002 · External reference
Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue
1999 · External reference
Intelligent albumin-MnO2 nanoparticles as pH-/H2O2-responsive dissociable nanocarriers to modulate tumor hypoxia for effective combination therapy
10.1002/adma.201601902 · 2016 · External reference
H2O2-responsive liposomal Nanoprobe for photoacoustic inflammation imaging and tumor Theranostics via in vivo chromogenic assay
10.1073/pnas.1701976114 · 2017 · External reference
Acidic stress promotes a glioma stem cell phenotype
10.1038/cdd.2010.150 · 2011 · External reference
Association between pH regulation of the tumor microenvironment and immunological state
10.3389/fonc.2023.1175563 · 2023 · External reference
The Warburg effect: essential part of metabolic reprogramming and central contributor to Cancer progression
10.1080/09553002.2019.1589653 · 2019 · External reference
Is hydrogen peroxide a suitable apoptosis inducer for all cell types?
2016 · External reference
Hypoxia/Reoxygenation-experienced Cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of Thymosin Beta-4
10.18632/oncotarget.3218 · 2015 · External reference
Tumor microenvironment and the response to anticancer therapy
10.4161/cbt.1.5.157 · 2002 · External reference
Tumor cycling hypoxia induces Chemoresistance in glioblastoma Multiforme by upregulating the expression and function of ABCB1
10.1093/neuonc/nos195 · 2012 · External reference
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
10.1038/onc.2009.252 · 2009 · External reference
Regulation of Glut1 mRNA by hypoxia-inducible Factor-1: interaction between H-ras and hypoxia
10.1074/jbc.m010144200 · 2001 · External reference
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
10.1215/s1152851704001115 · 2005 · External reference
Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, Pseudoprogression, and as a therapeutic target
10.1007/s11060-009-9827-2 · 2009 · External reference
Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells
10.1186/1756-8722-6-3 · 2013 · External reference
Temozolomide in the era of precision medicine
10.1158/0008-5472.can-16-2983 · 2017 · External reference
Hypoxia induces immunosuppression, metastasis and drug resistance in pancreatic cancers
10.1016/j.canlet.2023.216345 · 2023 · External reference
Mismatch repair as a dynamic and clinically actionable vulnerability in Cancer
10.1158/0008-5472.can-25-2255 · 2025 · External reference
Harnessing Ferroptosis to transform glioblastoma therapy and surmount treatment resistance
10.1038/s41420-025-02744-x · 2025 · External reference
NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug Temozolomide and its interaction with DNA
10.1021/bi00197a003 · 1994 · External reference
A review of approaches to potentiate the activity of Temozolomide against glioblastoma to overcome resistance
10.3390/ijms25063217 · 2024 · External reference
Carbon Nanosphere based bifunctional oxidoreductase Nano-catalytic agent to mitigate hypoxia in Cancer cells
10.1016/j.ijbiomac.2023.123466 · 2023 · External reference
Bioinspired metal-free fluorescent carbon Nanozyme with dual catalytic activity to confront cellular oxidative damage
10.1021/acsami.1c03130 · 2021 · External reference
Carbon nanomaterials as functional biomimetics: unveiling synthesis, and factors affecting their nanozyme potential
2025 · External reference
Carbon dots confined in N-doped carbon as peroxidase-like nanozyme for detection of gastric cancer relevant D-amino acids
2022 · External reference
Manganese-doped carbon dots with catalase-like activity enable MRI-guided enhanced photodynamic therapy
10.1016/j.colsurfb.2024.114398 · 2025 · External reference
Carbon dots as light-responsive oxidase-like nanozyme for colorimetric detection of total antioxidant capacity in fruits
2023 · External reference
Carbon dot superoxide dismutase nanozyme enhances reactive oxygen species scavenging in diabetic skin wound repair
10.1016/j.jare.2025.03.049 · 2025 · External reference
One-step, reagent-free construction of nano-enzyme as visual and reusable biosensor for oxidase substrates
10.1016/j.aca.2023.342008 · 2024 · External reference
Nanoengineered polyphenol-quantum dot conjugates inhibit biofilm protein-Aβ42 heterotypic fibrillogenesis, restore synaptic transmission, and suppress apoptosis in Alzheimer’s disease
10.1021/acschemneuro.5c00467 · 2025 · External reference
Spheroid-based drug screen: considerations and practical approach
10.1038/nprot.2008.226 · 2009 · External reference
Effects of hypoxia and nanocarrier size on pH-responsive nano-delivery system to solid tumors
10.1038/s41598-021-98638-w · 2021 · External reference
Phytochemical and pharmacological profile of Vitex negundo
10.1002/ptr.5303 · 2015 · External reference
Antidiabetic functionality of Vitex negundo L. leaves based on UHPLC-QTOF-MS/MS based bioactives profiling and molecular docking insights
10.1016/j.indcrop.2020.112445 · 2020 · External reference
Nanoenabled sequestration of redox copper modulates lysozyme aggregation and maintains lipid homeostasis to alleviate mitochondrial health
10.1002/smll.202508683 · 2025 · External reference
Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis
10.1038/s41598-020-76824-6 · 2020 · External reference
Highly expressive Bienzyme and Photothermal effect co-enabled by the co–O–Mn bridge for potentiating 1550 nm light-triggered photodynamic therapy
10.1021/jacs.5c22189 · 2026 · External reference
Effect of polyethylene glycol on the crystallization and impact properties of Polylactide-based blends
10.1002/pat.3475 · 2015 · External reference
Pollen-derived microcapsules for aspirin microencapsulation: in vitro release and Physico-chemical studies
10.1039/d2ra02888c · 2022 · External reference
Fine-tuning pyridinic nitrogen in nitrogen-doped porous carbon nanostructures for boosted peroxidase-like activity and sensitive biosensing
10.34133/2020/8202584 · 2020 · External reference
Nanozymes expanding the boundaries of biocatalysis
10.1038/s41467-025-62063-8 · 2025 · External reference
Molecular-level insights into intrinsic peroxidase-like activity of nanocarbon oxides
10.1002/chem.201404647 · 2015 · External reference
Reaction mechanisms and kinetics of nanozymes: insights from theory and computation
10.1002/adma.202211151 · 2024 · External reference
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
10.1016/j.molcel.2005.03.008 · 2005 · External reference
Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance
10.1111/j.1349-7006.2004.tb02214.x · 2004 · External reference
Temozolomide and pituitary tumors: current understanding, unresolved issues, and future directions
10.3389/fendo.2018.00318 · 2018 · External reference
Crystal engineering of stable Temozolomide Cocrystals
10.1002/asia.201200205 · 2012 · External reference
Five Cocrystal forms of antitumor drug Temozolomide with p-Hydroxybenzoic acid: structure, computational analysis, characterizations, stability, and transformation
10.1021/acs.cgd.2c00866 · 2022 · External reference
Theoretical and experimental Cocrystal screening of Temozolomide with a series of phenolic acids, promising Cocrystal Coformers
10.1016/j.cclet.2023.109032 · 2024 · External reference
Role of hydroxyl, superoxide, and nitrate radicals on the fate of bromide ions in photocatalytic TiO2 suspensions
10.1021/acscatal.0c02010 · 2020 · External reference
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
10.1038/nnano.2007.260 · 2007 · External reference
Co3O4 nanoparticles with multi-enzyme activities and their application in Immunohistochemical assay
10.1021/am405009f · 2014 · External reference
Fe− O−Mo site-activated nanozymes for bienzymatic/upconversion synergistic catalytic anticancer therapy
10.1002/anie.202511471 · 2025 · External reference
Temozolomide resistance mechanisms: unveiling the role of translesion DNA polymerase kappa in glioblastoma spheroids in vitro
10.1042/bsr20230667 · 2024 · External reference
Structurally modified dipyrazinylpyridine-based homoleptic cu (II) complexes: comparative cytotoxic evaluation in breast cancer cell lines
10.1039/d5dt01877c · 2025 · External reference
Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes
10.1016/j.ejpb.2008.05.017 · 2008 · External reference
Hypoxia signaling in human health and diseases: implications and prospects for therapeutics
10.1038/s41392-022-01080-1 · 2022 · External reference
Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape
10.1186/s13045-022-01292-6 · 2022 · External reference
Effects of some growth factors and cytokines on the expression of the repair enzyme MGMT and protein MARP in human cells in vitro
10.1007/s10528-018-9854-9 · 2018 · External reference
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
1993 · External reference
Poly(ADP-ribose): novel functions for an old molecule
10.1038/nrm1963 · 2006 · External reference
