Research graph
References from Organelle-targeted nanomedicine for metabolic reprogramming in regenerative medicine. Local targets link to admitted publications; unresolved targets remain external evidence.
How do organelle-targeting nanotherapeutics treat inflammatory diseases? A comprehensive review of the literature
10.2147/ijn.s516260 · 2025 · External reference
Metabolic (re)programming in skeletal stem cell populations
2024 · External reference
piRNAs are regulators of metabolic reprogramming in stem cells
10.1038/s41467-024-52709-4 · 2024 · External reference
Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
10.1038/s41392-022-01243-0 · 2022 · External reference
Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors
10.3389/fcell.2025.1609082 · 2025 · External reference
The metabolic programming of stem cells
10.1101/gad.293167.116 · 2017 · External reference
10.20517/2347-9264.2024.166
10.20517/2347-9264.2024.166 · External reference
Anti-Senescent Biomaterials for Breaking Intervertebral Disc Degeneration
10.1016/j.eng.2025.07.015 · 2025 · External reference
Decellularized extracellular matrix: Advanced bioplatforms for functional tissue restoration via innovative decellularization techniques
10.1016/j.bmt.2025.100131 · 2026 · External reference
Organelle transporters and inter-organelle communication as drivers of metabolic regulation and cellular homeostasis
10.1016/j.molmet.2022.101481 · 2022 · External reference
Endocytosis and Organelle Targeting of Nanomedicines in Cancer Therapy
10.2147/ijn.s274289 · 2020 · External reference
Organelle targeting: third level of drug targeting
2013 · External reference
Metabolic reprogramming of neural stem cells by chiral nanofiber for spinal cord injury
10.1021/acsnano.4c15770 · 2025 · External reference
Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD
10.3389/fcell.2025.1718799 · 2025 · External reference
An understanding of mitochondria and its role in targeting nanocarriers for diagnosis and treatment of cancer
2021 · External reference
Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history
10.1089/ten.tea.2011.0285 · 2012 · External reference
Endoplasmic reticulum stress: a novel targeted approach to repair bone defects by regulating osteogenesis and angiogenesis
10.1186/s12967-023-04328-8 · 2023 · External reference
Molecular Perspective of Nanoparticle Mediated Therapeutic Targeting in Breast Cancer: An Odyssey of Endoplasmic Reticulum Unfolded Protein Response (UPR(ER)) and Beyond
10.3390/biomedicines9060635 · 2021 · External reference
Endoplasmic Reticulum Stress in Neurodegenerative Diseases
10.3390/jdad1020006 · 2024 · External reference
Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants
10.1155/2013/956792 · 2013 · External reference
Organelle communication networks rewire to support lipid metabolism during neuronal differentiation
2026 · External reference
Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases
2022 · External reference
Positioning regulation of organelle network via Chinese microneedle
10.1126/sciadv.adl3063 · 2024 · External reference
Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity
10.3389/fcell.2020.00591 · 2020 · External reference
The role of mitochondria in stem cell fate and aging
10.1242/dev.143420 · 2018 · External reference
Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging
10.1126/science.aag3048 · 2018 · External reference
Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation
10.1155/2018/9131397 · 2018 · External reference
Mitochondrial dynamics govern whole-body regeneration through stem cell pluripotency and mitonuclear balance
10.1038/s41467-024-54720-1 · 2024 · External reference
Mitochondrial Function in Muscle Stem Cell Fates
10.3389/fcell.2020.00480 · 2020 · External reference
Autophagy in adult stem cell homeostasis, aging, and disease therapy
10.1186/s13619-025-00224-2 · 2025 · External reference
Mitochondrial-activity-driven hematopoietic stem cell fate and lineage choice is first established in the aorta-gonad-mesonephros
10.1016/j.celrep.2025.116296 · 2025 · External reference
Mitochondrial regulation in stem cells
10.1016/j.tcb.2023.10.003 · 2024 · External reference
Autophagy and Stem Cells: Self-Eating for Self-Renewal
10.3389/fcell.2020.00138 · 2020 · External reference
Ischaemia-reperfusion injury in liver transplantation–from bench to bedside
10.1038/nrgastro.2012.225 · 2013 · External reference
β-Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome
10.2337/db13-0717 · 2014 · External reference
The role of the endoplasmic reticulum stress in stemness, pluripotency and development
10.1016/j.ejcb.2016.02.002 · 2016 · External reference
Veratric acid alleviates liver ischemia/reperfusion injury by activating the Nrf2 signaling pathway
2021 · External reference
Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair
10.1016/j.devcel.2020.03.002 · 2020 · External reference
Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
10.1016/j.devcel.2024.06.020 · 2024 · External reference
Peroxisome quality control and dysregulated lipid metabolism in neurodegenerative diseases
10.1038/s12276-020-00503-9 · 2020 · External reference
Organelle remodeling in somatic cell reprogramming
10.1093/jmcb/mjaa032 · 2020 · External reference
Design Considerations for Organ-Selective Nanoparticles
10.1021/acsnano.5c00484 · 2025 · External reference
vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles
10.1021/nn901146y · 2010 · External reference
Organelle-oriented nanomedicines in tumor therapy: Targeting, escaping, or collaborating?
2025 · External reference
Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting
10.1038/s41392-020-00342-0 · 2020 · External reference
Nanoparticle organelle targeting kinetics: a discussion on application
2025 · External reference
Organelle-Targeting Nanoparticles
2025 · External reference
Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques
10.1016/j.addr.2024.115195 · 2024 · External reference
Fast and effective mitochondrial delivery of ω-Rhodamine-B-polysulfobetaine-PEG copolymers
10.1038/s41598-018-19598-2 · 2018 · External reference
Mitochondria-Targeted Nanomedicine for Enhanced Efficacy of Cancer Therapy
10.3389/fbioe.2021.720508 · 2021 · External reference
Triphenylphosphine-Based Mitochondrial Targeting Nanocarriers: Advancing Cancer Therapy
2025 · External reference
KDEL Receptors: Pathophysiological Functions, Therapeutic Options, and Biotechnological Opportunities
10.3390/biomedicines10061234 · 2022 · External reference
Self-Assembled Nanomaterials for ER-Targeted Cancer Therapy: From Molecular Design to Therapeutic Applications
10.1021/acs.biomac.6c00174 · 2026 · External reference
Endoplasmic reticulum-targeted biomimetic nanoparticles induce apoptosis and ferroptosis by regulating endoplasmic reticulum function in colon cancer
10.1016/j.jconrel.2024.09.018 · 2024 · External reference
Lysosome-Targeting Nanochimeras Attenuating Liver Fibrosis by Interconnected Transforming Growth Factor-β Reduction and Activin Receptor-Like Kinase 5 Degradation
10.1021/acsnano.5c00985 · 2025 · External reference
Nanomaterials Respond to Lysosomal Function for Tumor Treatment
10.3390/cells11213348 · 2022 · External reference
Nucleus-targeted delivery of nitric oxide in human mesenchymal stem cells enhances osteogenic differentiation
10.1016/j.bioorg.2023.106483 · 2023 · External reference
Intelligent nanotherapeutic strategies for the delivery of CRISPR system
10.1016/j.apsb.2022.12.013 · 2023 · External reference
Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy
10.1038/nnano.2016.62 · 2016 · External reference
Sequential Drug Delivery in Targeted Cancer Therapy
10.3390/pharmaceutics14030573 · 2022 · External reference
Nanocarriers transport across the gastrointestinal barriers: The contribution to oral bioavailability via blood circulation and lymphatic pathway
10.1016/j.addr.2023.115130 · 2023 · External reference
Challenges in development of nanoparticle-based therapeutics
10.1208/s12248-012-9339-4 · 2012 · External reference
Unresolved reference
External reference
Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases
10.1021/acsnano.5c00700 · 2025 · External reference
Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment
10.3390/ijms21176380 · 2020 · External reference
Mitochondrial-Targeting Drug-Loaded Nanoparticles Reprogram Macrophage Metabolism via ROS/NO Co-elimination for Diabetic Wound Healing
10.1021/acsami.5c19664 · 2025 · External reference
Mitochondria-targeted delivery strategies for age-related diseases
2026 · External reference
Advancements in mitochondrial-targeted nanotherapeutics: overcoming biological obstacles and optimizing drug delivery
2024 · External reference
Mitochondria targeted nanoparticles for the treatment of mitochondrial dysfunction-associated brain disorders
10.3389/fbioe.2025.1563701 · 2025 · External reference
Research progresses on mitochondrial-targeted biomaterials for bone defect repair
10.1093/rb/rbae082 · 2024 · External reference
Gold nanoparticles targeting the autophagy–lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy
10.1016/j.biomaterials.2022.121743 · 2022 · External reference
Nanomaterials-mediated lysosomal regulation: a robust protein-clearance approach for the treatment of Alzheimer's disease
10.4103/nrr.nrr-d-23-01736 · 2025 · External reference
Emerging nano-delivery systems for targeting mitochondria
10.1039/d5nr03935e · 2026 · External reference
Mitochondria-targeting materials and therapies for regenerative engineering
10.1016/j.biomaterials.2024.123023 · 2025 · External reference
Exosomes targeted towards applications in regenerative medicine
10.1002/nano.202000251 · 2021 · External reference
The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer
2025 · External reference
Clinical applications of stem cell-derived exosomes
10.1038/s41392-023-01704-0 · 2024 · External reference
Engineered mitochondria in diseases: mechanisms, strategies, and applications
10.1038/s41392-024-02081-y · 2025 · External reference
Mitochondria-enriched nanovesicles: A novel approach for treating radiation-induced skin injury
2025 · External reference
Decoding Organelle Interactions: Unveiling Molecular Mechanisms and Disease Therapies
10.1002/adbi.202300288 · 2024 · External reference
Correlation of organelle interactions in the development of non-alcoholic fatty liver disease
10.3389/fimmu.2025.1567743 · 2025 · External reference
DNA damage related crosstalk between the nucleus and mitochondria
10.1016/j.freeradbiomed.2016.11.050 · 2017 · External reference
Nuclear-mitochondrial interactions
10.3390/biom12030427 · 2022 · External reference
Cell- and subcellular organelle-targeting nanoparticle-mediated breast cancer therapy
10.3389/fphar.2023.1180794 · 2023 · External reference
Energy Metabolism in Mesenchymal Stem Cells During Osteogenic Differentiation
10.1089/scd.2015.0193 · 2016 · External reference
Metabolic reprogramming in skin wound healing
10.1093/burnst/tkad047 · 2024 · External reference
Metabolism in Human Mesenchymal Stromal Cells: A Missing Link Between hMSC Biomanufacturing and Therapy?
10.3389/fimmu.2019.00977 · 2019 · External reference
Lipid Metabolism in Cartilage Development, Degeneration, and Regeneration
10.3390/nu14193984 · 2022 · External reference
Harnessing nature's blueprint: Unlocking the potential of subcellular structure membrane-coated nanosystems for precision medicine
2026 · External reference
Mitochondria-Targeted Polyphenol-Cysteine Nanoparticles Regulating AMPK-Mediated Mitochondrial Homeostasis for Enhanced Bone Regeneration
10.1002/adfm.202402463 · 2024 · External reference
Biomimetic peroxisome targets myocardial injury and promotes heart repair and regeneration
10.1016/j.biomaterials.2025.123214 · 2025 · External reference
Mitochondrial Permeability Transition Pore: The Cardiovascular Disease's Molecular Achilles Heel
10.3390/biomedicines13123014 · 2025 · External reference
Mitochondria as a therapeutic target for cardiac ischemia‑reperfusion injury (Review).
10.3892/ijmm.2020.4823 · 2021 · External reference
New Insights into the Reparative Angiogenesis after Myocardial Infarction
10.3390/ijms241512298 · 2023 · External reference
Pioneering therapies for post-infarction angiogenesis: Insight into molecular mechanisms and preclinical studies
10.1016/j.biopha.2023.115306 · 2023 · External reference
Neurodegenerative Diseases - Is Metabolic Deficiency the Root Cause?
10.3389/fnins.2020.00213 · 2020 · External reference
Secondary Mitochondrial Dysfunction as a Cause of Neurodegenerative Dysfunction in Lysosomal Storage Diseases and an Overview of Potential Therapies
10.3390/ijms231810573 · 2022 · External reference
Mitochondrial dysfunction in diabetic ulcers: pathophysiological mechanisms and targeted therapeutic strategies
10.3389/fcell.2025.1625474 · 2025 · External reference
Mitochondria-targeted co-assembled nanosystem with multimodal mitochondrial DNA level control to alleviate inflammation and promote chronic wound healing
10.1016/j.biomaterials.2026.123981 · 2026 · External reference
Lysosomes as a therapeutic target
10.1038/s41573-019-0036-1 · 2019 · External reference
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection
10.1038/s41467-026-68318-2 · 2026 · External reference
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver
10.1101/gr.267013.120 · 2021 · External reference
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma
10.1002/hep.31391 · 2021 · External reference
Protective Effect of Mitochondria-Targeted Polydopamine Nanoparticles in Alleviating Hepatic Ischemia-Reperfusion Injury
2026 · External reference
Immunometabolism changes in fibrosis: from mechanisms to therapeutic strategies
10.3389/fphar.2023.1243675 · 2023 · External reference
Metabolic Reprogramming in Immune Response and Tissue Inflammation
10.1161/atvbaha.120.314037 · 2020 · External reference
Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis
10.1016/j.it.2023.10.004 · 2023 · External reference
Stem Cells Applications in Regenerative Medicine and Disease Therapeutics
10.1155/2016/6940283 · 2016 · External reference
Vivo Reprogramming of Tissue-Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering
2025 · External reference
Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm for regenerative medicine
10.7150/thno.72812 · 2022 · External reference
Recent Advances in Organelle-Targeted Drug Delivery: Precision Medicine at the Subcellular Level
2025 · External reference
Transformative Impact of Nanocarrier-Mediated Drug Delivery: Overcoming Biological Barriers and Expanding Therapeutic Horizons
10.1002/smsc.202400280 · 2024 · External reference
Membrane Trafficking and Subcellular Drug Targeting Pathways
10.3389/fphar.2020.00629 · 2020 · External reference
Alterations in Cellular Processes Involving Vesicular Trafficking and Implications in Drug Delivery
2018 · External reference
The impact of, and expectations for, lipid nanoparticle technology: From cellular targeting to organelle targeting
10.1016/j.jconrel.2024.05.006 · 2024 · External reference
Use of Biomarkers in Drug Development for Regulatory Purposes
10.1111/cts.70377 · 2025 · External reference
Ethical and Safety Issues of Stem Cell-Based Therapy
10.7150/ijms.21666 · 2018 · External reference
Organelle Targeted Drug Delivery: Key Challenges, Recent Advancements and Therapeutic Implications
10.2174/0118715303282573240112104035 · 2024 · External reference
Microenvironment-responsive nanomedicines: a promising direction for tissue regeneration
2024 · External reference
Nanomedicine-based immunotherapy for tissue regeneration
10.1093/burnst/tkaf015 · 2025 · External reference
Decoding Organelle Interactions: Unveiling Molecular Mechanisms and Disease Therapies
10.1002/adbi.202300288 · ExternalCitation · doi-reference
Mitochondria-Targeted Polyphenol-Cysteine Nanoparticles Regulating AMPK-Mediated Mitochondrial Homeostasis for Enhanced Bone Regeneration
10.1002/adfm.202402463 · ExternalCitation · doi-reference
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma
10.1002/hep.31391 · ExternalCitation · doi-reference
Exosomes targeted towards applications in regenerative medicine
10.1002/nano.202000251 · ExternalCitation · doi-reference
Transformative Impact of Nanocarrier-Mediated Drug Delivery: Overcoming Biological Barriers and Expanding Therapeutic Horizons
10.1002/smsc.202400280 · ExternalCitation · doi-reference
Nanocarriers transport across the gastrointestinal barriers: The contribution to oral bioavailability via blood circulation and lymphatic pathway
10.1016/j.addr.2023.115130 · ExternalCitation · doi-reference
Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques
10.1016/j.addr.2024.115195 · ExternalCitation · doi-reference
Intelligent nanotherapeutic strategies for the delivery of CRISPR system
10.1016/j.apsb.2022.12.013 · ExternalCitation · doi-reference
Gold nanoparticles targeting the autophagy–lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy
10.1016/j.biomaterials.2022.121743 · ExternalCitation · doi-reference
Mitochondria-targeting materials and therapies for regenerative engineering
10.1016/j.biomaterials.2024.123023 · ExternalCitation · doi-reference
Biomimetic peroxisome targets myocardial injury and promotes heart repair and regeneration
10.1016/j.biomaterials.2025.123214 · ExternalCitation · doi-reference
Mitochondria-targeted co-assembled nanosystem with multimodal mitochondrial DNA level control to alleviate inflammation and promote chronic wound healing
10.1016/j.biomaterials.2026.123981 · ExternalCitation · doi-reference
Nucleus-targeted delivery of nitric oxide in human mesenchymal stem cells enhances osteogenic differentiation
10.1016/j.bioorg.2023.106483 · ExternalCitation · doi-reference
Pioneering therapies for post-infarction angiogenesis: Insight into molecular mechanisms and preclinical studies
10.1016/j.biopha.2023.115306 · ExternalCitation · doi-reference
Decellularized extracellular matrix: Advanced bioplatforms for functional tissue restoration via innovative decellularization techniques
10.1016/j.bmt.2025.100131 · ExternalCitation · doi-reference
Mitochondrial-activity-driven hematopoietic stem cell fate and lineage choice is first established in the aorta-gonad-mesonephros
10.1016/j.celrep.2025.116296 · ExternalCitation · doi-reference
Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair
10.1016/j.devcel.2020.03.002 · ExternalCitation · doi-reference
Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
10.1016/j.devcel.2024.06.020 · ExternalCitation · doi-reference
The role of the endoplasmic reticulum stress in stemness, pluripotency and development
10.1016/j.ejcb.2016.02.002 · ExternalCitation · doi-reference
Anti-Senescent Biomaterials for Breaking Intervertebral Disc Degeneration
10.1016/j.eng.2025.07.015 · ExternalCitation · doi-reference
DNA damage related crosstalk between the nucleus and mitochondria
10.1016/j.freeradbiomed.2016.11.050 · ExternalCitation · doi-reference
Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis
10.1016/j.it.2023.10.004 · ExternalCitation · doi-reference
The impact of, and expectations for, lipid nanoparticle technology: From cellular targeting to organelle targeting
10.1016/j.jconrel.2024.05.006 · ExternalCitation · doi-reference
Endoplasmic reticulum-targeted biomimetic nanoparticles induce apoptosis and ferroptosis by regulating endoplasmic reticulum function in colon cancer
10.1016/j.jconrel.2024.09.018 · ExternalCitation · doi-reference
Organelle transporters and inter-organelle communication as drivers of metabolic regulation and cellular homeostasis
10.1016/j.molmet.2022.101481 · ExternalCitation · doi-reference
Mitochondrial regulation in stem cells
10.1016/j.tcb.2023.10.003 · ExternalCitation · doi-reference
Self-Assembled Nanomaterials for ER-Targeted Cancer Therapy: From Molecular Design to Therapeutic Applications
10.1021/acs.biomac.6c00174 · ExternalCitation · doi-reference
Mitochondrial-Targeting Drug-Loaded Nanoparticles Reprogram Macrophage Metabolism via ROS/NO Co-elimination for Diabetic Wound Healing
10.1021/acsami.5c19664 · ExternalCitation · doi-reference
Metabolic reprogramming of neural stem cells by chiral nanofiber for spinal cord injury
10.1021/acsnano.4c15770 · ExternalCitation · doi-reference
Design Considerations for Organ-Selective Nanoparticles
10.1021/acsnano.5c00484 · ExternalCitation · doi-reference
Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases
10.1021/acsnano.5c00700 · ExternalCitation · doi-reference
Lysosome-Targeting Nanochimeras Attenuating Liver Fibrosis by Interconnected Transforming Growth Factor-β Reduction and Activin Receptor-Like Kinase 5 Degradation
10.1021/acsnano.5c00985 · ExternalCitation · doi-reference
vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles
10.1021/nn901146y · ExternalCitation · doi-reference
Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy
10.1038/nnano.2016.62 · ExternalCitation · doi-reference
Ischaemia-reperfusion injury in liver transplantation–from bench to bedside
10.1038/nrgastro.2012.225 · ExternalCitation · doi-reference
Peroxisome quality control and dysregulated lipid metabolism in neurodegenerative diseases
10.1038/s12276-020-00503-9 · ExternalCitation · doi-reference
Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting
10.1038/s41392-020-00342-0 · ExternalCitation · doi-reference
Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
10.1038/s41392-022-01243-0 · ExternalCitation · doi-reference
Clinical applications of stem cell-derived exosomes
10.1038/s41392-023-01704-0 · ExternalCitation · doi-reference
Engineered mitochondria in diseases: mechanisms, strategies, and applications
10.1038/s41392-024-02081-y · ExternalCitation · doi-reference
piRNAs are regulators of metabolic reprogramming in stem cells
10.1038/s41467-024-52709-4 · ExternalCitation · doi-reference
Mitochondrial dynamics govern whole-body regeneration through stem cell pluripotency and mitonuclear balance
10.1038/s41467-024-54720-1 · ExternalCitation · doi-reference
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection
10.1038/s41467-026-68318-2 · ExternalCitation · doi-reference
Lysosomes as a therapeutic target
10.1038/s41573-019-0036-1 · ExternalCitation · doi-reference
Fast and effective mitochondrial delivery of ω-Rhodamine-B-polysulfobetaine-PEG copolymers
10.1038/s41598-018-19598-2 · ExternalCitation · doi-reference
Emerging nano-delivery systems for targeting mitochondria
10.1039/d5nr03935e · ExternalCitation · doi-reference
Energy Metabolism in Mesenchymal Stem Cells During Osteogenic Differentiation
10.1089/scd.2015.0193 · ExternalCitation · doi-reference
Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history
10.1089/ten.tea.2011.0285 · ExternalCitation · doi-reference
Metabolic reprogramming in skin wound healing
10.1093/burnst/tkad047 · ExternalCitation · doi-reference
Nanomedicine-based immunotherapy for tissue regeneration
10.1093/burnst/tkaf015 · ExternalCitation · doi-reference
Organelle remodeling in somatic cell reprogramming
10.1093/jmcb/mjaa032 · ExternalCitation · doi-reference
Research progresses on mitochondrial-targeted biomaterials for bone defect repair
10.1093/rb/rbae082 · ExternalCitation · doi-reference
The metabolic programming of stem cells
10.1101/gad.293167.116 · ExternalCitation · doi-reference
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver
10.1101/gr.267013.120 · ExternalCitation · doi-reference
Use of Biomarkers in Drug Development for Regulatory Purposes
10.1111/cts.70377 · ExternalCitation · doi-reference
Positioning regulation of organelle network via Chinese microneedle
10.1126/sciadv.adl3063 · ExternalCitation · doi-reference
Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging
10.1126/science.aag3048 · ExternalCitation · doi-reference
Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants
10.1155/2013/956792 · ExternalCitation · doi-reference
Stem Cells Applications in Regenerative Medicine and Disease Therapeutics
10.1155/2016/6940283 · ExternalCitation · doi-reference
Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation
10.1155/2018/9131397 · ExternalCitation · doi-reference
Metabolic Reprogramming in Immune Response and Tissue Inflammation
10.1161/atvbaha.120.314037 · ExternalCitation · doi-reference
Endoplasmic reticulum stress: a novel targeted approach to repair bone defects by regulating osteogenesis and angiogenesis
10.1186/s12967-023-04328-8 · ExternalCitation · doi-reference
Autophagy in adult stem cell homeostasis, aging, and disease therapy
10.1186/s13619-025-00224-2 · ExternalCitation · doi-reference
Challenges in development of nanoparticle-based therapeutics
10.1208/s12248-012-9339-4 · ExternalCitation · doi-reference
The role of mitochondria in stem cell fate and aging
10.1242/dev.143420 · ExternalCitation · doi-reference
10.20517/2347-9264.2024.166
10.20517/2347-9264.2024.166 · ExternalCitation · doi-reference
Endocytosis and Organelle Targeting of Nanomedicines in Cancer Therapy
10.2147/ijn.s274289 · ExternalCitation · doi-reference
How do organelle-targeting nanotherapeutics treat inflammatory diseases? A comprehensive review of the literature
10.2147/ijn.s516260 · ExternalCitation · doi-reference
Organelle Targeted Drug Delivery: Key Challenges, Recent Advancements and Therapeutic Implications
10.2174/0118715303282573240112104035 · ExternalCitation · doi-reference
β-Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome
10.2337/db13-0717 · ExternalCitation · doi-reference
Mitochondria-Targeted Nanomedicine for Enhanced Efficacy of Cancer Therapy
10.3389/fbioe.2021.720508 · ExternalCitation · doi-reference
Mitochondria targeted nanoparticles for the treatment of mitochondrial dysfunction-associated brain disorders
10.3389/fbioe.2025.1563701 · ExternalCitation · doi-reference
Autophagy and Stem Cells: Self-Eating for Self-Renewal
10.3389/fcell.2020.00138 · ExternalCitation · doi-reference
Mitochondrial Function in Muscle Stem Cell Fates
10.3389/fcell.2020.00480 · ExternalCitation · doi-reference
Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity
10.3389/fcell.2020.00591 · ExternalCitation · doi-reference
Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors
10.3389/fcell.2025.1609082 · ExternalCitation · doi-reference
Mitochondrial dysfunction in diabetic ulcers: pathophysiological mechanisms and targeted therapeutic strategies
10.3389/fcell.2025.1625474 · ExternalCitation · doi-reference
Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD
10.3389/fcell.2025.1718799 · ExternalCitation · doi-reference
Metabolism in Human Mesenchymal Stromal Cells: A Missing Link Between hMSC Biomanufacturing and Therapy?
10.3389/fimmu.2019.00977 · ExternalCitation · doi-reference
Correlation of organelle interactions in the development of non-alcoholic fatty liver disease
10.3389/fimmu.2025.1567743 · ExternalCitation · doi-reference
Neurodegenerative Diseases - Is Metabolic Deficiency the Root Cause?
10.3389/fnins.2020.00213 · ExternalCitation · doi-reference
Membrane Trafficking and Subcellular Drug Targeting Pathways
10.3389/fphar.2020.00629 · ExternalCitation · doi-reference
Cell- and subcellular organelle-targeting nanoparticle-mediated breast cancer therapy
10.3389/fphar.2023.1180794 · ExternalCitation · doi-reference
Immunometabolism changes in fibrosis: from mechanisms to therapeutic strategies
10.3389/fphar.2023.1243675 · ExternalCitation · doi-reference
Nuclear-mitochondrial interactions
10.3390/biom12030427 · ExternalCitation · doi-reference
KDEL Receptors: Pathophysiological Functions, Therapeutic Options, and Biotechnological Opportunities
10.3390/biomedicines10061234 · ExternalCitation · doi-reference
Mitochondrial Permeability Transition Pore: The Cardiovascular Disease's Molecular Achilles Heel
10.3390/biomedicines13123014 · ExternalCitation · doi-reference
Molecular Perspective of Nanoparticle Mediated Therapeutic Targeting in Breast Cancer: An Odyssey of Endoplasmic Reticulum Unfolded Protein Response (UPR(ER)) and Beyond
10.3390/biomedicines9060635 · ExternalCitation · doi-reference
Nanomaterials Respond to Lysosomal Function for Tumor Treatment
10.3390/cells11213348 · ExternalCitation · doi-reference
Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment
10.3390/ijms21176380 · ExternalCitation · doi-reference
Secondary Mitochondrial Dysfunction as a Cause of Neurodegenerative Dysfunction in Lysosomal Storage Diseases and an Overview of Potential Therapies
10.3390/ijms231810573 · ExternalCitation · doi-reference
New Insights into the Reparative Angiogenesis after Myocardial Infarction
10.3390/ijms241512298 · ExternalCitation · doi-reference
Endoplasmic Reticulum Stress in Neurodegenerative Diseases
10.3390/jdad1020006 · ExternalCitation · doi-reference
Lipid Metabolism in Cartilage Development, Degeneration, and Regeneration
10.3390/nu14193984 · ExternalCitation · doi-reference
Sequential Drug Delivery in Targeted Cancer Therapy
10.3390/pharmaceutics14030573 · ExternalCitation · doi-reference
Mitochondria as a therapeutic target for cardiac ischemia‑reperfusion injury (Review).
10.3892/ijmm.2020.4823 · ExternalCitation · doi-reference
Nanomaterials-mediated lysosomal regulation: a robust protein-clearance approach for the treatment of Alzheimer's disease
10.4103/nrr.nrr-d-23-01736 · ExternalCitation · doi-reference
Ethical and Safety Issues of Stem Cell-Based Therapy
10.7150/ijms.21666 · ExternalCitation · doi-reference
Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm for regenerative medicine
10.7150/thno.72812 · ExternalCitation · doi-reference