Research graph
References from Glucose dendrimer-ketamine conjugates enable precise and efficacious neuromodulation while preserving neuronal network dynamics. Local targets link to admitted publications; unresolved targets remain external evidence.
Ketamine: a tale of two enantiomers
10.1177/0269881120959644 · 2021 · External reference
Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al
10.1038/s41380-022-01629-0 · 2023 · External reference
Ketamine and its two enantiomers in anesthesiology and psychiatry: a historical review and future directions
10.1016/j.jatmed.2024.07.001 · 2024 · External reference
Ketamine: current applications in anesthesia, pain, and critical care
10.4103/0259-1162.143110 · 2014 · External reference
Bridging rapid and sustained antidepressant effects of ketamine
10.1016/j.molmed.2023.02.003 · 2023 · External reference
Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide
10.12688/f1000research.14344.1 · 2018 · External reference
Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms
10.1038/s41386-023-01629-w · 2024 · External reference
Ketamine and the future of rapid-acting antidepressants
10.1146/annurev-clinpsy-072120-014126 · 2021 · External reference
Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine
10.1016/j.bcp.2020.113935 · 2020 · External reference
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression
10.1038/s41386-020-0663-6 · 2020 · External reference
Ketamine treatment for depression: a review
10.1007/s44192-022-00012-3 · 2022 · External reference
Major depressive disorder: hypothesis, mechanism, prevention and treatment
10.1038/s41392-024-01738-y · 2024 · External reference
The role of ketamine in treatment-resistant depression: a systematic review
10.2174/1570159x12666140619204251 · 2014 · External reference
Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials
10.1038/s41386-024-02044-5 · 2025 · External reference
Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions
10.1002/wps.21120 · 2023 · External reference
Intranasal Esketamine (Spravato(TM)) for Use in Treatment-Resistant Depression In Conjunction With an Oral Antidepressant
2019 · External reference
Side-effects associated with ketamine use in depression: a systematic review
10.1016/s2215-0366(17)30272-9 · 2018 · External reference
Ketamine-Induced Hallucinations
10.1159/000438675 · 2015 · External reference
Ketamine abuse potential and use disorder
10.1016/j.brainresbull.2016.05.016 · 2016 · External reference
The abuse liability of ketamine: a scoping review of preclinical and clinical studies
10.1016/j.jpsychires.2022.04.035 · 2022 · External reference
The abuse liability of ketamine: a scoping review of preclinical and clinical studies
2022 · External reference
Ketamine: NMDA receptors and beyond
10.1523/jneurosci.1547-16.2016 · 2016 · External reference
Attenuation of antidepressant effects of ketamine by opioid receptor antagonism
10.1176/appi.ajp.2018.18020138 · 2018 · External reference
Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites
10.1038/s41398-019-0624-1 · 2019 · External reference
Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review
10.1177/2040622315579059 · 2015 · External reference
Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity
10.1016/j.drudis.2016.01.016 · 2016 · External reference
Dendrimer nanotherapy for severe COVID-19 attenuates inflammation and neurological injury markers and improves outcomes in a phase2a clinical trial
10.1126/scitranslmed.abo2652 · 2022 · External reference
A new era in posterior segment ocular drug delivery: translation of systemic, cell-targeted, dendrimer-based therapies
10.1016/j.addr.2023.115005 · 2023 · External reference
Unresolved reference
2024 · External reference
Efficient intracellular delivery of CRISPR-Cas9 ribonucleoproteins using dendrimer nanoparticles for robust genomic editing
10.1016/j.nantod.2025.102654 · 2025 · External reference
Unresolved reference
External reference
Targeted neuronal delivery of creatine using glucose dendrimer for creatine-transporter deficiency and neonatal brain injury
10.1007/s40883-025-00500-2 · 2026 · External reference
Development of a novel glucose-dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders
10.1002/btm2.10655 · 2024 · External reference
Glucose transporters: physiological and pathological roles
10.1007/s12551-015-0186-2 · 2016 · External reference
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
10.1038/nature17998 · 2016 · External reference
Norketamine, the Main Metabolite of Ketamine, Induces Mitochondria-Dependent and ER Stress-Triggered Apoptotic Death in Urothelial Cells via a Ca2+-Regulated ERK1/2-Activating Pathway
10.3390/ijms23094666 · 2022 · External reference
Psychedelics promote structural and functional neural plasticity
10.1016/j.celrep.2018.05.022 · 2018 · External reference
Revealing neuronal function through microelectrode array recordings
10.3389/fnins.2014.00423 · 2015 · External reference
Multi-electrode array technologies for neuroscience and cardiology
10.1038/nnano.2012.265 · 2013 · External reference
The evolution of the pilocarpine animal model of status epilepticus
2020 · External reference
Ketamine protects against pilocarpine-induced oxidative stress and metabolic enzyme disturbances during epileptogenesis in the epilepsy model
10.1007/s11094-024-03239-2 · 2024 · External reference
The role of inflammation in epilepsy
10.1038/nrneurol.2010.178 · 2011 · External reference
Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models
10.1111/epi.12960 · 2015 · External reference
Neuroimmunology of status epilepticus
10.1016/j.yebeh.2023.109095 · 2023 · External reference
ER to synapse trafficking of NMDA receptors
10.3389/fncel.2014.00394 · 2014 · External reference
Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells
10.1002/sctm.17-0059 · 2017 · External reference
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
2020 · External reference
Sex and hormonal influences on seizures and epilepsy
10.1016/j.yhbeh.2012.03.018 · 2013 · External reference
Sex-related differences in glial fibrillary acidic protein-positive GABA regulate neuropathology following pilocarpine-induced status epilepticus
10.1016/j.neuroscience.2021.08.002 · 2021 · External reference
Factors affecting outcomes of pilocarpine treatment in a mouse model of temporal lobe epilepsy
10.1016/j.eplepsyres.2012.05.012 · 2012 · External reference
Intranasal administration of CNS therapeutics to awake mice
10.3791/4440-v · 2013 · External reference
Effect of lacosamide on neuroinflammation-mediated seizures comorbid with depression in C57BL/6 mice- Role of kynurenine pathway
10.1016/j.yebeh.2021.108262 · 2021 · External reference
Loss of Protection by Antiepileptic Drugs in Lipopolysaccharide-primed Pilocarpine-induced Status Epilepticus is Mediated via Inflammatory Signalling
10.1016/j.neuroscience.2020.06.024 · 2020 · External reference
Modification of seizure activity by electrical stimulation. II. Motor seizure
10.1016/0013-4694(72)90177-0 · 1972 · External reference
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model
10.1016/s0014-4886(03)00086-4 · 2003 · External reference
Quantifying microglia morphology from photomicrographs of immunohistochemistry prepared tissue using imageJ
10.3791/57648 · 2018 · External reference
Development of a novel glucose-dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders
10.1002/btm2.10655 · ExternalCitation · doi-reference
Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells
10.1002/sctm.17-0059 · ExternalCitation · doi-reference
Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions
10.1002/wps.21120 · ExternalCitation · doi-reference
Ketamine protects against pilocarpine-induced oxidative stress and metabolic enzyme disturbances during epileptogenesis in the epilepsy model
10.1007/s11094-024-03239-2 · ExternalCitation · doi-reference
Glucose transporters: physiological and pathological roles
10.1007/s12551-015-0186-2 · ExternalCitation · doi-reference
Targeted neuronal delivery of creatine using glucose dendrimer for creatine-transporter deficiency and neonatal brain injury
10.1007/s40883-025-00500-2 · ExternalCitation · doi-reference
Ketamine treatment for depression: a review
10.1007/s44192-022-00012-3 · ExternalCitation · doi-reference
Modification of seizure activity by electrical stimulation. II. Motor seizure
10.1016/0013-4694(72)90177-0 · ExternalCitation · doi-reference
A new era in posterior segment ocular drug delivery: translation of systemic, cell-targeted, dendrimer-based therapies
10.1016/j.addr.2023.115005 · ExternalCitation · doi-reference
Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine
10.1016/j.bcp.2020.113935 · ExternalCitation · doi-reference
Ketamine abuse potential and use disorder
10.1016/j.brainresbull.2016.05.016 · ExternalCitation · doi-reference
Psychedelics promote structural and functional neural plasticity
10.1016/j.celrep.2018.05.022 · ExternalCitation · doi-reference
Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity
10.1016/j.drudis.2016.01.016 · ExternalCitation · doi-reference
Factors affecting outcomes of pilocarpine treatment in a mouse model of temporal lobe epilepsy
10.1016/j.eplepsyres.2012.05.012 · ExternalCitation · doi-reference
Ketamine and its two enantiomers in anesthesiology and psychiatry: a historical review and future directions
10.1016/j.jatmed.2024.07.001 · ExternalCitation · doi-reference
The abuse liability of ketamine: a scoping review of preclinical and clinical studies
10.1016/j.jpsychires.2022.04.035 · ExternalCitation · doi-reference
Bridging rapid and sustained antidepressant effects of ketamine
10.1016/j.molmed.2023.02.003 · ExternalCitation · doi-reference
Efficient intracellular delivery of CRISPR-Cas9 ribonucleoproteins using dendrimer nanoparticles for robust genomic editing
10.1016/j.nantod.2025.102654 · ExternalCitation · doi-reference
Loss of Protection by Antiepileptic Drugs in Lipopolysaccharide-primed Pilocarpine-induced Status Epilepticus is Mediated via Inflammatory Signalling
10.1016/j.neuroscience.2020.06.024 · ExternalCitation · doi-reference
Sex-related differences in glial fibrillary acidic protein-positive GABA regulate neuropathology following pilocarpine-induced status epilepticus
10.1016/j.neuroscience.2021.08.002 · ExternalCitation · doi-reference
Effect of lacosamide on neuroinflammation-mediated seizures comorbid with depression in C57BL/6 mice- Role of kynurenine pathway
10.1016/j.yebeh.2021.108262 · ExternalCitation · doi-reference
Neuroimmunology of status epilepticus
10.1016/j.yebeh.2023.109095 · ExternalCitation · doi-reference
Sex and hormonal influences on seizures and epilepsy
10.1016/j.yhbeh.2012.03.018 · ExternalCitation · doi-reference
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model
10.1016/s0014-4886(03)00086-4 · ExternalCitation · doi-reference
Side-effects associated with ketamine use in depression: a systematic review
10.1016/s2215-0366(17)30272-9 · ExternalCitation · doi-reference
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
10.1038/nature17998 · ExternalCitation · doi-reference
Multi-electrode array technologies for neuroscience and cardiology
10.1038/nnano.2012.265 · ExternalCitation · doi-reference
The role of inflammation in epilepsy
10.1038/nrneurol.2010.178 · ExternalCitation · doi-reference
Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al
10.1038/s41380-022-01629-0 · ExternalCitation · doi-reference
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression
10.1038/s41386-020-0663-6 · ExternalCitation · doi-reference
Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms
10.1038/s41386-023-01629-w · ExternalCitation · doi-reference
Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials
10.1038/s41386-024-02044-5 · ExternalCitation · doi-reference
Major depressive disorder: hypothesis, mechanism, prevention and treatment
10.1038/s41392-024-01738-y · ExternalCitation · doi-reference
Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites
10.1038/s41398-019-0624-1 · ExternalCitation · doi-reference
Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models
10.1111/epi.12960 · ExternalCitation · doi-reference
Dendrimer nanotherapy for severe COVID-19 attenuates inflammation and neurological injury markers and improves outcomes in a phase2a clinical trial
10.1126/scitranslmed.abo2652 · ExternalCitation · doi-reference
Ketamine and the future of rapid-acting antidepressants
10.1146/annurev-clinpsy-072120-014126 · ExternalCitation · doi-reference
Ketamine-Induced Hallucinations
10.1159/000438675 · ExternalCitation · doi-reference
Attenuation of antidepressant effects of ketamine by opioid receptor antagonism
10.1176/appi.ajp.2018.18020138 · ExternalCitation · doi-reference
Ketamine: a tale of two enantiomers
10.1177/0269881120959644 · ExternalCitation · doi-reference
Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review
10.1177/2040622315579059 · ExternalCitation · doi-reference
Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide
10.12688/f1000research.14344.1 · ExternalCitation · doi-reference
Ketamine: NMDA receptors and beyond
10.1523/jneurosci.1547-16.2016 · ExternalCitation · doi-reference
The role of ketamine in treatment-resistant depression: a systematic review
10.2174/1570159x12666140619204251 · ExternalCitation · doi-reference
ER to synapse trafficking of NMDA receptors
10.3389/fncel.2014.00394 · ExternalCitation · doi-reference
Revealing neuronal function through microelectrode array recordings
10.3389/fnins.2014.00423 · ExternalCitation · doi-reference
Norketamine, the Main Metabolite of Ketamine, Induces Mitochondria-Dependent and ER Stress-Triggered Apoptotic Death in Urothelial Cells via a Ca2+-Regulated ERK1/2-Activating Pathway
10.3390/ijms23094666 · ExternalCitation · doi-reference
Intranasal administration of CNS therapeutics to awake mice
10.3791/4440-v · ExternalCitation · doi-reference
Quantifying microglia morphology from photomicrographs of immunohistochemistry prepared tissue using imageJ
10.3791/57648 · ExternalCitation · doi-reference
Ketamine: current applications in anesthesia, pain, and critical care
10.4103/0259-1162.143110 · ExternalCitation · doi-reference
