Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Transient ocular hypertension drives delayed and IOP-independent retinal neurodegeneration. Local targets link to admitted publications; unresolved targets remain external evidence.
Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury
10.1093/brain/awy142 · 2018 · External reference
Mimicking chronic glaucoma over 6 months with a single intracameral injection of dexamethasone/fibronectin-loaded PLGA microspheres
10.1080/10717544.2022.2096712 · 2022 · External reference
AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
10.1186/s13024-021-00466-z · 2021 · External reference
Addressing neurodegeneration in glaucoma: mechanisms, challenges, and treatments
10.1016/j.preteyeres.2024.101261 · 2024 · External reference
Müller cells in the healthy and diseased retina
10.1016/j.preteyeres.2006.05.003 · 2006 · External reference
Prevalence of glaucoma in an urban west African population: the Tema eye survey
10.1001/jamaophthalmol.2013.1686 · 2013 · External reference
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage
10.1016/j.preteyeres.2004.06.001 · 2005 · External reference
A molecular switch for neuroprotective astrocyte reactivity
10.1038/s41586-023-06935-3 · 2024 · External reference
High-efficiency ocular delivery of brain-derived neurotrophic factor and Oligomycin for neuroprotection in glaucoma
10.1002/adma.202500623 · 2025 · External reference
Neuroserpin gene therapy inhibits retinal ganglion cell apoptosis and promotes functional preservation in glaucoma
10.1016/j.ymthe.2023.03.008 · 2023 · External reference
Retinoid X receptor alpha overexpression protects retinal ganglion cells and modulates inflammatory response in experimental glaucoma
10.1016/j.ymthe.2025.08.034 · 2025 · External reference
Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling
10.1016/j.neuron.2015.02.017 · 2015 · External reference
Insulin restores retinal ganglion cell functional connectivity and promotes visual recovery in glaucoma
10.1126/sciadv.adl5722 · 2024 · External reference
Enhanced retinal ganglion cell survival in Glaucoma by hypoxic Postconditioning after disease onset
10.1007/s13311-014-0330-x · 2015 · External reference
Downregulation of splicing regulator RBFOX1 compromises visual depth perception
10.1371/journal.pone.0200417 · 2018 · External reference
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells
10.1016/j.cell.2021.06.031 · 2021 · External reference
Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucoma
10.1186/s12974-021-02366-x · 2021 · External reference
Retinal ganglion cell circuits and glial interactions in humans and mice
10.1016/j.tins.2024.09.010 · 2024 · External reference
Effect of anesthesia on intraocular pressure measured with continuous wireless telemetry in nonhuman Primates
10.1167/iovs.19-27758 · 2019 · External reference
Glaucoma: now and beyond
10.1016/s0140-6736(23)01289-8 · 2023 · External reference
Longitudinal changes of retinal nerve Fiber layer and ganglion cell-inner plexiform layer in highly myopic Glaucoma: a 3-year cohort study
10.1016/j.ophtha.2025.01.014 · 2025 · External reference
Antioxidant effect of gallic acid on retinal ganglion cells in glaucoma model
10.1038/s41598-024-65965-7 · 2024 · External reference
Diagnosis and pathogenesis of glaucomatous optic neuropathy: morphological aspects
10.1016/s1350-9462(99)00002-6 · 2000 · External reference
Restoring AIBP expression in the retina provides neuroprotection in glaucoma
10.1016/j.ymthe.2025.05.009 · 2025 · External reference
Retinal microglia: just bystander or target for therapy?
10.1016/j.preteyeres.2014.11.004 · 2015 · External reference
Impact of glaucomatous ganglion cell damage on central visual function
10.1146/annurev-vision-110223-123044 · 2024 · External reference
Relative efficacy of prostaglandins
10.1016/j.ophtha.2009.02.009 · 2009 · External reference
Lhx2 promotes axon regeneration of adult retinal ganglion cells and rescues neurodegeneration in mouse models of glaucoma
2024 · External reference
Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure
10.1016/j.ajo.2004.04.022 · 2004 · External reference
The effect of A2A receptor antagonist on microglial activation in experimental glaucoma
10.1167/iovs.15-18024 · 2016 · External reference
Regeneration and functional recovery of the completely transected optic nerve in adult rats by CNTF-chitosan
10.1038/s41392-022-01289-0 · 2023 · External reference
Effects of NGF-chitosan on alleviating secondary degeneration and repairing primary degeneration after expanded partial optic nerve transection
10.1007/s11427-024-2756-9 · 2025 · External reference
Microglial cGAS-STING signaling underlies glaucoma pathogenesis
2024 · External reference
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma
10.1186/s13024-020-00400-9 · 2020 · External reference
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma
10.1016/j.preteyeres.2023.101169 · 2023 · External reference
Reliability and sensitivity of the TonoLab rebound tonometer in awake Brown Norway rats
10.1167/iovs.08-2465 · 2009 · External reference
Selective vulnerability of specific retinal ganglion cell types and synapses after transient ocular hypertension
10.1523/jneurosci.0940-16.2016 · 2016 · External reference
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway
10.1126/science.1161566 · 2008 · External reference
Protecting the retinal neurons from glaucoma: lowering ocular pressure is not enough
10.1016/j.phrs.2012.03.002 · 2012 · External reference
Molecular classification and comparative taxonomics of foveal and peripheral cells in primate retina
10.1016/j.cell.2019.01.004 · 2019 · External reference
Lifetime risk of blindness in open-angle glaucoma
10.1016/j.ajo.2013.05.027 · 2013 · External reference
The visual physiology of the wild type mouse determined with pattern VEPs
10.1016/s0042-6989(99)00022-x · 1999 · External reference
Purinergic signaling in retinal degeneration and regeneration
10.1016/j.neuropharm.2015.05.005 · 2016 · External reference
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure
10.1016/j.ophtha.2003.05.019 · 2004 · External reference
Glaucoma in adults-screening, diagnosis, and management: a review
10.1001/jama.2020.21899 · 2021 · External reference
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines
10.1016/j.ophtha.2007.10.004 · 2008 · External reference
Molecular regulation of neuroinflammation in glaucoma: current knowledge and the ongoing search for new treatment targets
10.1016/j.preteyeres.2021.100998 · 2022 · External reference
Glia-neuron interactions in the mammalian retina
10.1016/j.preteyeres.2015.06.003 · 2016 · External reference
The pathophysiology and treatment of glaucoma: a review
10.1001/jama.2014.3192 · 2014 · External reference
Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma
10.1186/s13024-016-0091-6 · 2016 · External reference
Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo
10.1016/j.expneurol.2009.05.008 · 2009 · External reference
The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration
10.1038/ncomms6416 · 2014 · External reference
Microglia versus monocytes: distinct roles in degenerative diseases of the retina
10.1016/j.tins.2020.03.012 · 2020 · External reference
A rat model of glaucoma induced by episcleral vein ligation
10.1016/j.exer.2006.03.014 · 2006 · External reference
Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse
10.7554/elife.45881 · 2019 · External reference