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References from Loss of Snord115 mitigates Snord116-driven sleep abnormalities in mouse models of Prader-Willi syndrome. Local targets link to admitted publications; unresolved targets remain external evidence.
Neural substrates of awakening probed with optogenetic control of hypocretin neurons
10.1038/nature06310 · 2007 · External reference
Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice
10.1111/j.1460-9568.2004.03749.x · 2004 · External reference
Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader–Willi syndrome
10.1093/molbev/msab348 · 2022 · External reference
Unresolved reference
2024 · External reference
Mouse models of Prader-Willi syndrome: a systematic review
10.1016/j.yfrne.2013.01.002 · 2013 · External reference
Highly restricted deletion of the SNORD116 region is implicated in Prader-Willi syndrome
10.1038/ejhg.2014.103 · 2015 · External reference
The evolving neurobiology of early-life stress
10.1016/j.neuron.2025.02.016 · 2025 · External reference
Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution
10.1093/nar/gkac404 · 2022 · External reference
Prader Willi syndrome and excessive daytime sleepiness
10.1016/j.smrv.2007.08.005 · 2008 · External reference
10.21203/rs.3.rs-8523796/v1
10.21203/rs.3.rs-8523796/v1 · External reference
Prader-Willi syndrome
2012 · External reference
Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay
10.1002/wrna.1417 · 2017 · External reference
Targeted ribose methylation of RNA in vivo directed by tailored antisense RNA guides
10.1038/383732a0 · 1996 · External reference
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization
10.1073/pnas.250426397 · 2000 · External reference
Brief report: parental descriptions of sleep problems in children with autism, Down syndrome, and Prader–Willi syndrome
10.1016/j.ridd.2004.12.003 · 2006 · External reference
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex
10.1038/s41467-018-03676-0 · 2018 · External reference
A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism
10.1093/hmg/ddp263 · 2009 · External reference
Melanin-concentrating hormone (MCH) modulates the activity of dorsal raphe neurons
10.1016/j.brainres.2014.12.032 · 2015 · External reference
SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and Hyperphagia in mice
10.1371/journal.pone.0001709 · 2008 · External reference
Paternally inherited microdeletion at 15q11.2 confirms a significant role for the SNORD116 C/D box snoRNA cluster in Prader-Willi syndrome
10.1038/ejhg.2010.102 · 2010 · External reference
SNORD116 deletions cause Prader-Willi syndrome with a mild phenotype and macrocephaly
10.1111/cge.13005 · 2017 · External reference
Genetic variation in EEG activity during sleep in inbred mice
1998 · External reference
Differential regulation of non-protein coding RNAs from Prader-Willi syndrome locus
10.1038/srep06445 · 2014 · External reference
Prevalence and phenotype of sleep disorders in 60 adults with Prader–Willi syndrome
10.1093/sleep/zsx162 · 2017 · External reference
Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader-Willi syndrome
10.1093/nar/gkae1129 · 2024 · External reference
Characterization of the melanin-concentrating hormone neurons activated during paradoxical sleep hypersomnia in rats
10.1002/cne.21482 · 2007 · External reference
Prader-Willi syndrome and atypical submicroscopic 15q11-q13 deletions with or without imprinting defects
10.1016/j.ejmg.2016.09.017 · 2016 · External reference
Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model
2020 · External reference
The origin of excessive daytime sleepiness in the Prader-Willi syndrome
10.1111/j.1365-2788.1993.tb00323.x · 1993 · External reference
Roles of SNORD115 and SNORD116 ncRNA clusters during neuronal differentiation
10.1038/s41467-024-54573-8 · 2024 · External reference
Developmental trends of sleep-disordered breathing in Prader-Willi syndrome: the role of obesity
10.1002/ajmg.1320560215 · 1995 · External reference
Entrainment of temperature and activity rhythms to restricted feeding in orexin knock out mice
10.1016/j.brainres.2008.02.026 · 2008 · External reference
The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C
10.1126/science.1118265 · 2006 · External reference
Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs
10.1016/s0092-8674(00)81308-2 · 1996 · External reference
Dietary conjugated linoleic acid reduces body weight and fat in Snord116m+/p- and Snord116m−/p- mouse models of Prader-Willi syndrome
10.3390/nu14040860 · 2022 · External reference
Natural hypothalamic circuit dynamics underlying object memorization
10.1038/s41467-019-10484-7 · 2019 · External reference
A comprehensive review of genetically engineered mouse models for Prader-Willi syndrome research
10.3390/ijms22073613 · 2021 · External reference
Effects on sleep of melanin-concentrating hormone (MCH) microinjections into the dorsal raphe nucleus
10.1016/j.brainres.2009.02.010 · 2009 · External reference
Deletion of the Snord116/SNORD116 alters sleep in mice and patients with Prader-Willi syndrome
10.5665/sleep.5542 · 2016 · External reference
Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
10.1523/jneurosci.1887-05.2005 · 2005 · External reference
Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances
2022 · External reference
Evolutionary and biological insights into the paternally expressed Snord116-Ipw-Snord115 gene array at the imprinted Prader-Willi syndrome domain
2026 · External reference
Increased REM sleep after intra-locus coeruleus nucleus microinjection of melanin-concentrating hormone (MCH) in the rat
10.1016/j.pnpbp.2014.09.003 · 2015 · External reference
Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat
10.1371/journal.pone.0019600 · 2011 · External reference
Hypocretin deficiency in Prader–Willi syndrome
10.1111/j.1468-1331.2004.00969.x · 2005 · External reference
Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes
10.1146/annurev.genom.2.1.153 · 2001 · External reference
Decline of CSF orexin (hypocretin) levels in Prader-Willi syndrome
10.1002/ajmg.a.37542 · 2016 · External reference
Loss of Snord116 alters cortical neuronal activity in mice: a preclinical investigation of Prader–Willi syndrome
10.1093/hmg/ddaa084 · 2020 · External reference
Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
2020 · External reference
Melanin-concentrating hormone (MCH) in the median raphe nucleus: fibers, receptors and cellular effects
10.1016/j.peptides.2019.170249 · 2020 · External reference
Hypocretins/orexins and narcolepsy: from molecules to disease
2003 · External reference
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome
10.1172/jci97007 · 2018 · External reference
A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure
10.1093/hmg/ddt281 · 2013 · External reference
Snord116 is critical in the regulation of food intake and body weight
2016 · External reference
Mechanisms of activation of the paternally expressed genes by the Prader-Willi imprinting center in the Prader-Willi/Angelman syndromes domains
10.1073/pnas.1116661109 · 2012 · External reference
Sleep and behaviour disturbance in Prader–Willi syndrome: a questionnaire study
10.1046/j.1365-2788.1999.043005380.x · 1999 · External reference
Maternal transcription of non-protein coding RNAs from the PWS-critical region rescues growth retardation in mice
10.1038/srep20398 · 2016 · External reference
The IC-SNURF–SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A
10.1093/hmg/10.23.2687 · 2001 · External reference
Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster
10.1038/ng.158 · 2008 · External reference
What can we learn from PWS and SNORD116 genes about the pathophysiology of addictive disorders?
10.1038/s41380-020-00917-x · 2021 · External reference
Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive behavior in Prader-Willi syndrome
10.1038/s41380-024-02542-4 · 2024 · External reference
Oxytocin-MCH circuit regulates monosynaptic inputs to MCH neurons and modulates social recognition memory
10.1016/j.neuropharm.2020.108423 · 2021 · External reference
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
10.1371/journal.pone.0020360 · 2011 · External reference
Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement
10.1016/j.biopsych.2009.12.035 · 2010 · External reference
Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation
10.1371/journal.pgen.1006804 · 2017 · External reference
Neuropsychiatric features of Prader-Willi syndrome
10.1002/ajmg.a.62662 · 2022 · External reference
Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation
10.1371/journal.pgen.0030235 · 2007 · External reference
Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats
10.1038/s41467-023-37344-9 · 2023 · External reference
Neuronal activity of orexin and non-orexin waking-active neurons during wake–sleep states in the mouse
10.1016/j.neuroscience.2008.02.058 · 2008 · External reference
Prader–Willi-like phenotype caused by an atypical 15q11.2 microdeletion
10.3390/genes11020128 · 2020 · External reference
Sleep in the Prader-Willi syndrome: clinical and polygraphic findings
10.1001/archneur.1984.04050150072020 · 1984 · External reference
A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep
10.1186/1471-2202-4-19 · 2003 · External reference
ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs
10.1083/jcb.200411129 · 2005 · External reference
Long nuclear-retained non-coding RNAs and allele-specific higher-order chromatin organization at imprinted snoRNA gene arrays
10.1242/jcs.054957 · 2010 · External reference
The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA
10.1002/wrna.117 · 2012 · External reference
Unresolved reference
2025 · External reference
Long noncoding RNAs with snoRNA ends
10.1016/j.molcel.2012.07.033 · 2012 · External reference
Comparison of mouse models reveals a molecular distinction between psychotic illness in PWS and schizophrenia
10.1038/s41398-021-01561-x · 2021 · External reference
