Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Gene-environment interaction between perinatal oxytocin exposure and Pten mutation shapes epigenetic reprogramming of oxytocin signaling and behavior in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
The effect of maternal oxytocin induction during birth on early neonatal pain and stress: a quasi-experimental study
10.1177/10998004241289896 · 2025 · External reference
The association between labor induction and autism Spectrum disorders among children: a Meta-analysis
10.2174/1573396317666210521155111 · 2021 · External reference
The feto-placental metabolome of spontaneous labour is not reproduced following induction of labour
10.1016/j.placenta.2022.10.005 · 2022 · External reference
Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum - a systematic review with implications for the function of the oxytocinergic system
10.1186/s12884-022-05221-w · 2023 · External reference
PTEN interacts with histone H1 and controls chromatin condensation
10.1016/j.celrep.2014.08.008 · 2014 · External reference
Autism-relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons
10.1002/aur.1641 · 2016 · External reference
Maternal oxytocin treatment at birth increases epigenetic age in male offspring
10.1002/dev.22452 · 2024 · External reference
The role of prenatal, obstetric and neonatal factors in the development of autism
10.1007/s10803-010-1114-8 · 2011 · External reference
Social amnesia in mice lacking the oxytocin gene
10.1038/77040 · 2000 · External reference
Oxytocin in the medial amygdala is essential for social recognition in the mouse
10.1523/jneurosci.21-20-08278.2001 · 2001 · External reference
Cumulative risk of the oxytocin receptor gene interacts with prenatal exposure to oxytocin receptor antagonist to predict children's social communication development
10.1002/aur.2111 · 2019 · External reference
Oxytocin, neural plasticity, and social behavior
10.1146/annurev-neuro-102320-102847 · 2021 · External reference
Oxytocin exposure in labor and its relationship with cognitive impairment and the genetic architecture of autism
10.1007/s10803-021-05409-7 · 2023 · External reference
PTEN gene and autism: genetic underpinnings and neurodevelopmental impacts
10.3390/genes16091061 · 2025 · External reference
Labor induction with oxytocin in pregnant rats is not associated with oxidative stress in the fetal brain
10.1038/s41598-022-07236-x · 2022 · External reference
Oxytocin-induced birth causes sex-specific behavioral and brain connectivity changes in developing rat offspring
10.1016/j.isci.2024.108960 · 2024 · External reference
A mathematical model relating Pitocin use during labor with offspring autism development in terms of oxytocin receptor desensitization in the fetal brain
10.1155/2019/8276715 · 2019 · External reference
Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
10.1186/1741-7015-7-62 · 2009 · External reference
Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53
10.1093/hmg/ddq434 · 2011 · External reference
Oxytocin induced labor causes region and sex-specific transient oligodendrocyte cell death in neonatal mouse brain
10.1111/jog.14149 · 2020 · External reference
The hippocampal CA2 region is essential for social memory
10.1038/nature13028 · 2014 · External reference
Maternal oxytocin administration modulates gene expression in the brains of perinatal mice
10.1515/jpm-2020-0525 · 2022 · External reference
Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome
10.1038/ncomms13421 · 2016 · External reference
Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression
10.1038/s41398-021-01472-x · 2021 · External reference
Epigenetic modifications in stress response genes associated with childhood trauma
2019 · External reference
Oxytocin levels tend to be lower in autistic children: a meta-analysis of 31 studies
10.1177/13623613211034375 · 2021 · External reference
Exogenous oxytocin administration during labor and autism spectrum disorder
10.1016/j.ajogmf.2023.101010 · 2023 · External reference
Behavioral and epigenetic consequences of oxytocin treatment at birth
10.1126/sciadv.aav2244 · 2019 · External reference
Neuroanatomical and functional consequences of oxytocin treatment at birth in prairie voles
10.1016/j.psyneuen.2023.106025 · 2023 · External reference
The regulation of oxytocin and oxytocin receptor in human placenta according to gestational age
10.1530/jme-16-0223 · 2017 · External reference
Bismark: a flexible aligner and methylation caller for bisulfite-Seq applications
10.1093/bioinformatics/btr167 · 2011 · External reference
Pten regulates neuronal arborization and social interaction in mice
10.1016/j.neuron.2006.03.023 · 2006 · External reference
Fast gapped-read alignment with Bowtie 2
10.1038/nmeth.1923 · 2012 · External reference
Induction of labor in a contemporary obstetric cohort
10.1016/j.ajog.2012.03.014 · 2012 · External reference
Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function
10.1093/hmg/ddp220 · 2009 · External reference
Wired for motherhood: induction of maternal care but not maternal aggression in virgin female CD1 mice
10.3389/fnbeh.2015.00197 · 2015 · External reference
Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly
10.1002/aur.132 · 2010 · External reference
Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice
10.1016/j.psyneuen.2013.03.003 · 2013 · External reference
Association of labor induction with offspring risk of autism spectrum disorders
10.1001/jamapediatrics.2016.0965 · 2016 · External reference
Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder
10.1073/pnas.1402236111 · 2014 · External reference
Association of Labor Epidural Analgesia, oxytocin exposure, and risk of autism Spectrum disorders in children
10.1001/jamanetworkopen.2023.24630 · 2023 · External reference
Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity
10.1186/s13229-021-00448-4 · 2021 · External reference
Brief report: sex/gender differences in symptomology and camouflaging in adults with autism Spectrum disorder
10.1007/s10803-019-03998-y · 2019 · External reference
Hippocampus: molecular, cellular, and circuit features in anxiety
10.1007/s12264-023-01020-1 · 2023 · External reference
Intranasal oxytocin in children and adolescents with autism spectrum disorder
10.1056/nejmoa2103583 · 2021 · External reference
Trends in labor induction in the United States, 1989 to 2020
10.1097/nmc.0000000000000824 · 2022 · External reference
Involvement of the oxytocin system in the nucleus accumbens in the regulation of juvenile social novelty-seeking behavior
10.1016/j.yhbeh.2017.05.005 · 2017 · External reference
Signaling pathways in mouse and human trophoblast differentiation: a comparative review
10.1007/s00018-014-1794-x · 2015 · External reference
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
10.1073/pnas.0505312102 · 2005 · External reference
Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
10.1016/j.celrep.2022.111574 · 2022 · External reference
Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?
10.1186/s40246-017-0129-z · 2017 · External reference
Could oxytocin administration during labor contribute to autism and related behavioral disorders?--A look at the literature
10.1016/j.mehy.2004.03.008 · 2004 · External reference
Rates of induction of labor at 39 weeks and cesarean delivery following publication of the ARRIVE trial
10.1001/jamanetworkopen.2023.28274 · 2023 · External reference
Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial
10.1093/brain/awab291 · 2022 · External reference
The clinical spectrum of PTEN mutations
10.1146/annurev-med-052218-125823 · 2020 · External reference
Optimal dose of oxytocin to improve social impairments and repetitive behaviors in autism spectrum disorders: meta-analysis and dose-response meta-analysis of randomized controlled trials
2024 · External reference
Oxytocin is not associated with postpartum hemorrhage in labor augmentation in a retrospective cohort study in the United States
10.1016/j.ajog.2023.07.054 · 2024 · External reference