References

Non-coding RNAs in the brain-heart axis: the case of Parkinson’s disease

10.3390/ijms21186513 · 2020 · External reference

The RNA-binding protein NOVA-1 regulates circRNA expression, alternative splicing, and aging in Caenorhabditis elegans

10.1093/g3journal/jkag016 · 2026 · External reference

Amyotrophic lateral sclerosis: translating genetic discoveries into therapies

10.1038/s41576-023-00592-y · 2023 · External reference

Pathways for macrophage uptake of cell-free circular RNAs

10.1016/j.molcel.2024.04.022 · 2024 · External reference

Circular RNA expression and interaction patterns are perturbed in amyotrophic lateral sclerosis

10.3390/ijms232314665 · 2022 · External reference

Proteinopathies as hallmarks of impaired gene expression, proteostasis and mitochondrial function in amyotrophic lateral sclerosis

10.3389/fnins.2021.783624 · 2021 · External reference

Circulating blood circular RNA in Parkinson’s disease; from involvement in pathology to diagnostic tools in at-risk individuals

2024 · External reference

Circular RNA-Is the circle perfect?

10.3390/biom11121755 · 2021 · External reference

SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

10.1186/s13024-021-00475-y · 2021 · External reference

Inducible motor neuron differentiation of human induced pluripotent stem cells in vivo

10.1111/cpr.13319 · 2022 · External reference

FUS alters circRNA metabolism in human motor neurons carrying the ALS-linked P525L mutation

10.3390/ijms24043181 · 2023 · External reference

FUS alters circRNA metabolism in human motor neurons carrying the ALS-linked P525L mutation

10.3390/ijms24043181 · 2023 · External reference

RNALocate v2.0: an updated resource for RNA subcellular localization with increased coverage and annotation

10.1093/nar/gkab825 · 2022 · External reference

HMDD v4.0: a database for experimentally supported human microRNA-disease associations

10.1093/nar/gkad717 · 2024 · External reference

Circular RNAs as potential blood biomarkers in amyotrophic lateral sclerosis

10.1007/s12035-019-1627-x · 2019 · External reference

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

10.1038/ncomms14741 · 2017 · External reference

The role of non-coding RNAs in ALS

10.3390/genes16060623 · 2025 · External reference

Structure-mediated RNA decay by UPF1 and G3BP1

10.1016/j.molcel.2020.01.021 · 2020 · External reference

Motor neuron disease: pathophysiology, diagnosis, and management

10.1016/j.amjmed.2018.07.012 · 2019 · External reference

Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axis

10.7150/ijbs.58916 · 2021 · External reference

circBase: a database for circular RNAs

10.1261/rna.043687.113 · 2014 · External reference

Critical roles of circular RNA in tumor metastasis via acting as a sponge of miRNA/isomiR

10.3390/ijms23137024 · 2022 · External reference

ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs

10.1016/j.neures.2018.11.005 · 2019 · External reference

Mechanisms regulating abnormal circular RNA biogenesis in cancer

10.3390/cancers13164185 · 2021 · External reference

Mechanism and function of circular RNA in regulating solid tumor radiosensitivity

10.3390/ijms231810444 · 2022 · External reference

Advances in molecular pathology, diagnosis, and treatment of amyotrophic lateral sclerosis

10.1136/bmj-2023-075037 · 2023 · External reference

Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules

10.1016/j.molcel.2026.01.031 · 2026 · External reference

Amyotrophic lateral sclerosis and the innate immune system: protocol for establishing a biobank and statistical analysis plan

10.1136/bmjopen-2020-037753 · 2020 · External reference

NOVA2 regulates neural circRNA biogenesis

10.1093/nar/gkab523 · 2021 · External reference

Splicing players are differently expressed in sporadic amyotrophic lateral sclerosis molecular clusters and brain regions

10.3390/cells9010159 · 2020 · External reference

Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability

10.3389/fncel.2015.00225 · 2015 · External reference

Opposite interplay between PPAR gamma and canonical Wnt/beta-catenin pathway in amyotrophic lateral sclerosis

10.3389/fneur.2016.00100 · 2016 · External reference

The biogenesis, functions, and challenges of circular RNAs

10.1016/j.molcel.2018.06.034 · 2018 · External reference

MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis

10.1186/s12859-019-3105-x · 2019 · External reference

Energy homeostasis and abnormal RNA metabolism in amyotrophic lateral sclerosis

10.3389/fncel.2017.00126 · 2017 · External reference

Circular RNA: An emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines

10.1016/j.jconrel.2022.05.043 · 2022 · External reference

Personalized precision immunotherapy for amyotrophic lateral sclerosis (ALS)

10.1615/critrevimmunol.2023048372 · 2023 · External reference

ALS and FTD: where RNA metabolism meets protein quality control

10.1016/j.semcdb.2019.06.003 · 2020 · External reference

RummaGEO: automatic mining of human and mouse gene sets from GEO

2024 · External reference

Amyotrophic lateral sclerosis: a clinical review

10.1111/ene.14393 · 2020 · External reference

Specific expression and functions of circular RNAs

10.1038/s41418-022-00948-7 · 2022 · External reference

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

10.1371/journal.pmed.1000097 · 2009 · External reference

Tissue-selective regulation of protein homeostasis and unfolded protein response signalling in sporadic ALS

10.1111/jcmm.15170 · 2020 · External reference

Circular RNA expression in ALS is progressively deregulated and tissue-dependent

10.1186/s12864-025-11725-4 · 2025 · External reference

Updates on disease mechanisms and therapeutics for amyotrophic lateral sclerosis

10.3390/cells13110888 · 2024 · External reference

CircNetVis: an interactive web application for visualizing interaction networks of circular RNAs

10.1186/s12859-024-05646-4 · 2024 · External reference

Amyotrophic lateral sclerosis (ALS): an overview of genetic and metabolic signaling mechanisms

10.2174/0118715273315891240801065231 · 2025 · External reference

10.1093/nar/gkaa1100

10.1093/nar/gkaa1100 · 2021 · External reference

The link between oxidative stress, redox status, bioenergetics and mitochondria in the pathophysiology of ALS

10.3390/ijms22126352 · 2021 · External reference

RBPsuite 2.0: an updated RNA-protein binding site prediction suite with high coverage on species and proteins based on deep learning

10.1186/s12915-025-02182-2 · 2025 · External reference

UCSF Chimera--a visualization system for exploratory research and analysis

10.1002/jcc.20084 · 2004 · External reference

The DisGeNET knowledge platform for disease genomics: 2019 update

2020 · External reference

Aberrantly expressed Hsa_circ_0060762 and CSE1L as potential peripheral blood biomarkers for ALS

10.3390/biomedicines11051316 · 2023 · External reference

Circulating RNAs as potential biomarkers in amyotrophic lateral sclerosis

10.3390/ijms21051714 · 2020 · External reference

Mechanisms of circular RNA degradation

10.1038/s42003-022-04262-3 · 2022 · External reference

Advancements in genetic research and RNA therapy strategies for amyotrophic lateral sclerosis (ALS): current progress and future prospects

10.1007/s00415-025-12975-8 · 2025 · External reference

Circular RNA expression profiling by microarray-a technical and practical perspective

10.3390/biom13040679 · 2023 · External reference

STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

10.1093/nar/gky1131 · 2019 · External reference

Circular RNA as a potential biomarker for melanoma: a systematic review

2021 · External reference

Circ_0000099/miR-223-3p/CTGF regulates the growth, metastasis, and EMT processes in TGF-β2-stimulated human Lens epithelial cells

10.1080/02713683.2024.2357600 · 2024 · External reference

Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs

10.18632/aging.204450 · 2022 · External reference

Long non-coding RNAs in motor neuron development and disease

10.1111/jnc.15198 · 2021 · External reference

Circular RNA in diseased heart

10.3390/cells9051240 · 2020 · External reference

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

10.1038/s41467-021-25082-9 · 2021 · External reference

RNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma

10.1186/s12935-021-01852-9 · 2021 · External reference

circAtlas 3.0: a gateway to 3 million curated vertebrate circular RNAs based on a standardized nomenclature scheme

10.1093/nar/gkad770 · 2024 · External reference

Regulatory mechanism of circular RNAs in neurodegenerative diseases

10.1111/cns.14499 · 2024 · External reference

Gene set knowledge discovery with Enrichr

10.1002/cpz1.90 · 2021 · External reference

HDOCK: a web server for protein-protein and protein-DNA/RNA docking based on a hybrid strategy

10.1093/nar/gkx407 · 2017 · External reference

Circular RNA regulation of myogenesis

10.3390/cells8080885 · 2019 · External reference

Advances in circular RNA and its applications

10.7150/ijms.71840 · 2022 · External reference

Circular RNA circTRPS1-2 inhibits the proliferation and migration of esophageal squamous cell carcinoma by reducing the production of ribosomes

10.1038/s41420-023-01300-9 · 2023 · External reference

Circular RNA: metabolism, functions and interactions with proteins

10.1186/s12943-020-01286-3 · 2020 · External reference

New progresses of circular RNA biology: from nuclear export to degradation

10.1080/15476286.2020.1853977 · 2021 · External reference