Research graph
References from Foretinib triggers immunogenic cell death and enhances efficacy of anti-CD47 immunotherapy in colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2025
2025 · External reference
Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments
10.1007/s10555-023-10158-3 · 2024 · External reference
Current and emerging therapeutic approaches for colorectal cancer: a comprehensive review
10.4240/wjgs.v15.i4.495 · 2023 · External reference
Immunotherapy in colorectal cancer: statuses and strategies
2025 · External reference
New immunotherapy approaches for colorectal cancer: focusing on CAR-T cell, BiTE, and oncolytic viruses
10.1186/s12964-023-01430-8 · 2024 · External reference
Immunotherapy in microsatellite-stable colorectal cancer: strategies to overcome resistance
10.1016/j.critrevonc.2025.104775 · 2025 · External reference
Immune checkpoint inhibitors in pMMR/MSS colorectal cancer
10.1007/s12029-023-00927-2 · 2023 · External reference
Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors
10.1038/s41423-024-01245-8 · 2025 · External reference
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
10.1038/s41568-024-00674-x · 2024 · External reference
Detection of immunogenic cell death and its relevance for cancer therapy
10.1038/s41419-020-03221-2 · 2020 · External reference
Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors
10.1038/s41423-024-01245-8 · 2025 · External reference
The inducers of immunogenic cell death for tumor immunotherapy
10.5301/tj.5000675 · 2018 · External reference
Immunogenic cell death inducers:current advances and future perspectives
10.1016/j.ccr.2025.216846 · 2025 · External reference
Immunogenic cell death in colon cancer prevention and therapy
10.1002/mc.23183 · 2020 · External reference
Mechanism of action of the multikinase inhibitor Foretinib
10.4161/cc.10.23.18323 · 2011 · External reference
Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to Quizartinib and Gilteritinib
10.1158/0008-5472.can-23-1534 · 2024 · External reference
Foretinib is effective against triple-negative breast cancer cells MDA-MB-231 in vitro and in vivo by down-regulating p-MET/HGF signaling
10.3390/ijms24010757 · 2023 · External reference
Targeted dual inhibition of c-met/VEGFR2 signalling by foretinib improves antitumour effects of nanoparticle paclitaxel in gastric cancer models
10.1111/jcmm.16362 · 2021 · External reference
Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation
10.1016/j.jbc.2021.100515 · 2021 · External reference
Organic radiosensitizer with aggregation-induced emission characteristics for tumor ablation through synergistic apoptosis and immunogenic cell death
10.1021/acsnano.5c00942 · 2025 · External reference
Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies
10.1016/j.canlet.2018.08.028 · 2018 · External reference
CX3CL1 release during immunogenic apoptosis is associated with enhanced anti-tumour immunity
10.3389/fimmu.2024.1396349 · 2024 · External reference
Phagocytosis checkpoints as new targets for cancer immunotherapy
10.1038/s41568-019-0183-z · 2019 · External reference
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47
10.1126/scitranslmed.3001375 · 2010 · External reference
Lurbinectedin: an FDA-approved inducer of immunogenic cell death for the treatment of small-cell lung cancer
10.1080/2162402x.2020.1795995 · 2020 · External reference
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
10.1038/s41580-018-0089-8 · 2019 · External reference
Targeting apoptosis in cancer therapy
10.1038/s41571-020-0341-y · 2020 · External reference
Death receptor 5 rises to the occasion
10.1038/s41422-022-00772-1 · 2023 · External reference
Elucidation for modulation of death receptor (DR) 5 to strengthen apoptotic signals in cancer cells
10.1007/s12272-018-01103-y · 2019 · External reference
Cell death, therapeutics, and the immune response in cancer
10.1016/j.trecan.2023.02.001 · 2023 · External reference
Dendritic cells as shepherds of T cell immunity in cancer
10.1016/j.immuni.2023.08.014 · 2023 · External reference
Improvement strategy for immune checkpoint blockade: a focus on the combination with immunogenic cell death inducers
10.1016/j.canlet.2023.216167 · 2023 · External reference
CD47 as a potent target in cancer immunotherapy: a review
10.1016/j.bbcan.2025.189294 · 2025 · External reference
Targeting CD47-SIRPa axis shows potent preclinical anti-tumor activity as monotherapy and synergizes with PARP inhibition
10.1038/s41698-023-00418-4 · 2023 · External reference
CD47–SIRPα-targeted therapeutics: status and prospects
2022 · External reference
Disulfiram/copper induces immunogenic cell death and enhances CD47 blockade in hepatocellular carcinoma
10.3390/cancers14194715 · 2022 · External reference
PAMAM-based polymeric immunogenic cell death inducer to potentiate cancer immunotherapy
10.1021/jacs.4c11636 · 2024 · External reference
