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References from Senescence-associated prostate cancer cells promote fibroblast reprogramming and extracellular matrix remodeling. Local targets link to admitted publications; unresolved targets remain external evidence.
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The senescence-associated secretory phenotype: the dark side of tumor suppression
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From senescence to scarring: Exploring TGF-beta signaling in cellular aging, fibrotic remodeling, and pulmonary fibrosis
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Context-dependent effects of cellular senescence in cancer development
10.1038/bjc.2016.115 · 2016 · External reference
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
10.1172/jci40535 · 2010 · External reference
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
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Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
10.1038/s41585-023-00827-x · 2024 · External reference
p21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by Senolytic therapy
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A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
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Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer
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A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
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Senescent CAFs Mediate Immunosuppression and Drive Breast Cancer Progression
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Bibliometric Insights into Aging and Immune Function in Prostate Cancer: Focus on Chronic Inflammation
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A proteomic atlas of senescence-associated secretomes for aging biomarker development
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NOTCH1 mediates a switch between two distinct secretomes during senescence
10.1038/ncb3397 · 2016 · External reference
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
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The extracellular matrix modulates the hallmarks of cancer
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Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
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The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis
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The matrix in cancer
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Androgen deprivation-induced senescence confers sensitivity to a senolytic strategy in prostate cancer
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