Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from The impact of social isolation on the development of alcohol use and alcohol addiction-related processes in animals: A systematic review. Local targets link to admitted publications; unresolved targets remain external evidence.
Seminatural housing increases subsequent ethanol intake in male maudsley reactive rats
10.15288/jsa.1996.57.349 · 1996 · External reference
Effect of early rearing conditions on alcohol drinking and 5-HT 1A receptor function in C57BL/6J mice
10.1017/s1461145706007401 · 2007 · External reference
Re-socialization reduces social isolation-induced high alcohol preference and anxiety via possibly restoring dopamine-rewarding effects in the rat striatum
2025 · External reference
Prairie voles as a novel model of socially facilitated excessive drinking
10.1111/j.1369-1600.2010.00234.x · 2011 · External reference
Biological contribution to social influences on alcohol drinking: evidence from animal models
2010 · External reference
The importance of housing conditions on behavioral sensitization and tolerance to ethanol
10.1016/j.pbb.2005.07.009 · 2005 · External reference
Sex differences in stress-related psychiatric disorders: Neurobiological perspectives
2014 · External reference
Ethanol markedly increases “‘GABAergic’” neurosteroids in alcohol-preferring rats. In
10.1016/s0014-2999(99)00678-0 · 1999 · External reference
Effects of stress on alcohol drinking: a review of animal studies
10.1007/s00213-011-2443-9 · 2011 · External reference
Overcoming alcohol and other drug addiction as a process of social identity transition: The social identity model of recovery (SIMOR
2016 · External reference
Social isolation and expression of serotonergic neurotransmission-related genes in several brain areas of male mice
10.1111/j.1601-183x.2006.00280.x · 2007 · External reference
Network reset: a simplified overarching theory of locus coeruleus noradrenaline function
10.1016/j.tins.2005.09.002 · 2005 · External reference
Longitudinal relationship between drinking with peers, descriptive norms, and adolescent alcohol use
10.1007/s11121-013-0391-9 · 2014 · External reference
The neuroendocrinology of social isolation
10.1146/annurev-psych-010814-015240 · 2015 · External reference
Why may allopregnanolone help alleviate loneliness
10.1016/j.mehy.2015.09.004 · 2015 · External reference
Effects of voluntary adolescent intermittent alcohol exposure and social isolation on adult alcohol intake in male rats
10.1016/j.alcohol.2022.07.008 · 2022 · External reference
Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male long evans rats
2013 · External reference
Nuclear imaging of neuroinflammation: a comprehensive review of [ 11C]PK11195 challengers. In
10.1007/s00259-008-0908-9 · 2008 · External reference
Tryptophan hydroxylase-2: An emerging therapeutic target for stress disorders
2013 · External reference
Early social isolation increases persistence of alcohol-seeking behavior in alcohol-related contexts
10.1097/fbp.0000000000000213 · 2016 · External reference
Adolescent resilience to addiction: a social plasticity hypothesis
10.1016/s2352-4642(17)30148-7 · 2018 · External reference
The role of neuroimmune signaling in alcoholism
2017 · External reference
Adolescent social isolation increases binge-like alcohol drinking in male but not female high-alcohol-preferring mice
10.1093/alcalc/agae006 · 2024 · External reference
10.1126/science.1137073
10.1126/science.1137073 · External reference
Early life stress induces hyperactivity but not increased anxiety-like behavior or ethanol drinking in outbred heterogeneous stock rats
10.1016/j.alcohol.2020.11.007 · 2021 · External reference
Differential rearing conditions alter operant responding for ethanol in outbred rats
10.1111/j.1530-0277.2007.00466.x · 2007 · External reference
Alcohol and dopamine
1997 · External reference
Alcohol Binge Drinking and Anxiety-Like Behavior in Socialized Versus Isolated C57BL/6J Mice
10.1111/acer.14236 · 2020 · External reference
Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories - indications for novel treatments of addiction
2014 · External reference
Effects of Early Weaning and Social Isolation on Subsequent Alcohol Intake in Rats Effects of early weaning andsocialisolation on subsequent alcohol intake in rats
10.1016/s0741-8329(96)00141-3 · 1997 · External reference
Social Housing Leads to Increased Ethanol Intake in Male Mice Housed in Environmentally Enriched Cages
2021 · External reference
Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism
10.1126/science.1153813 · 2008 · External reference
The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement
10.1016/j.pharmthera.2004.06.002 · 2004 · External reference
Benzodiazepine interactions with gaba receptors. In
10.1016/0304-3940(84)90514-7 · 1984 · External reference
ORIGINAL INVESTIGATION Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats. In
1998 · External reference
Effects of Crowding on Alcohol Consumption By Rats
1975 · External reference
Early environmental experience alters baseline and ethanol-induced cognitive impulsivity: Relationship to forebrain 5-HT1A receptor binding
10.1016/j.bbr.2004.10.018 · 2005 · External reference
Cholinergic rescue of neurocognitive insult following third-trimester equivalent alcohol exposure in rats
2019 · External reference
Neuropeptides-an overview
10.1016/s0028-3908(00)00010-1 · 2000 · External reference
Social and environmental enrichment has different effects on ethanol and sucrose consumption in mice
10.1002/brb3.767 · 2017 · External reference
Motivation for alcohol becomes resistant to quinine adulteration after 3–4 months of intermittent alcohol self-administration
10.1111/j.1530-0277.2010.01241.x · 2010 · External reference
Social housing and alcohol drinking in male-female pairs of prairie voles (Microtus ochrogaster
10.1007/s00213-012-2836-4 · 2012 · External reference
Intravenous Ethanol Administration and Operant Self-Administration Alter Extracellular Norepinephrine Concentration in the Mesocorticolimbic Systems of Male Long Evans Rats
10.1111/acer.14397 · 2020 · External reference
Effects of chronic social isolation stress and alcohol on the reinforcing properties of ketamine in male and female rats
10.1523/eneuro.0452-24.2025 · 2025 · External reference
Effects of social housing on alcohol intake in mice depend on the non-social environment
2024 · External reference
Isolate Housing Alters Ethanol Sensitivity in Long-Sleep and Short-Sleep Mice
10.1016/0091-3057(90)90187-m · 1990 · External reference
Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala
10.1002/syn.21826 · 2015 · External reference
Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood
10.1111/acer.12555 · 2014 · External reference
Early-life social isolation stress increases kappa opioid receptor responsiveness and downregulates the dopamine system
10.1038/npp.2016.21 · 2016 · External reference
Neurocircuitry of addiction
2010 · External reference
Social separation increases alcohol consumption in rhesus monkeys
10.1007/bf00431706 · 1985 · External reference
Development and validation of the Dutch Social Attunement Questionnaire (SAQ
10.1111/sode.12652 · 2023 · External reference
Implicit social attunement and alcohol use: the effect of peer feedback on willingness to drink in social settings
10.1007/s11469-024-01371-4 · 2025 · External reference
10.1038/s41398-022-02100-y
10.1038/s41398-022-02100-y · External reference
Ethanol consumption of rats in individual, group, and colonial housing conditions
10.3758/bf03326448 · 1980 · External reference
Social isolation blunted the response of mesocortical dopaminergic neurons to chronic ethanol voluntary intake
2016 · External reference
Reward processing by the opioid system in the brain
10.1152/physrev.00005.2009 · 2009 · External reference
Individual differences in social play behaviour predict alcohol intake and control over alcohol seeking in rats
10.1007/s00213-021-05929-1 · 2021 · External reference
Early social isolation augments alcohol consumption in rats
10.1097/fbp.0000000000000165 · 2015 · External reference
Isolation rearing and hyperlocomotion are associated with reduced immediate early gene expression levels in the medial prefrontal cortex
10.1016/j.neuroscience.2006.11.063 · 2007 · External reference
The effect of isolation rearing on volitional ethanol consumption and central CCK/dopamine systems in Fawn-Hooded rats
10.1016/s0166-4328(02)00328-5 · 2003 · External reference
Adolescent social housing protects against adult emotional and cognitive deficits and alters the PFC and NAc transcriptome in male and female C57BL/6J mice
2023 · External reference
Chronic social isolation and chronic variable stress during early development induce later elevated ethanol intake in adult C57BL/6J mice
10.1016/j.alcohol.2010.08.017 · 2011 · External reference
Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice
10.1016/j.physbeh.2014.11.012 · 2015 · External reference
Paired Housing or a Socially-Paired Context Decreases Ethanol Conditioned Place Preference in Male Rats
10.3390/brainsci12111485 · 2022 · External reference
Unresolved reference
2025 · External reference
Exposure to an enriched environment reduces alcohol self-administration in Sardinian alcohol-preferring rats
2022 · External reference
Environmental enrichment augments binge-like alcohol drinking in Sardinian alcohol-preferring rats
10.1016/j.alcohol.2022.09.003 · 2022 · External reference
Early social isolation in male long-evans rats alters both appetitive and consummatory behaviors expressed during operant ethanol self-administration
10.1111/j.1530-0277.2008.00830.x · 2009 · External reference
Sex differences in ethanol consumption and drinking despite negative consequences following adolescent social isolation stress in male and female rats
2023 · External reference
Exploring the effects of adolescent social isolation stress on the serotonin system and ethanol-motivated behaviors
10.1007/s00213-025-06749-3 · 2025 · External reference
Social support and mental health during recovery from drug and alcohol problems
10.1080/16066359.2017.1421178 · 2018 · External reference
Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference
10.1111/j.1530-0277.1998.tb03952.x · 1998 · External reference
Neurobiological Bases of Alcohol Consumption After Social Stress
10.1007/7854_2021_273 · 2022 · External reference
The Role of Social Support in Motivating Reductions in Alcohol Use: A Test of Three Models of Social Support in Alcohol-Impaired Drivers
10.1111/acer.13911 · 2019 · External reference
The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence. In
10.1016/s0165-0173(01)00127-8 · 2001 · External reference
An enriched environment increases noradrenaline concentration in the mouse brain
10.1016/s0006-8993(01)03257-7 · 2002 · External reference
Extrasynaptic δ-containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake
10.1073/pnas.1016156108 · 2011 · External reference
Mental health and well-being during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study
10.1192/bjp.2020.212 · 2021 · External reference
Role of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent model
2017 · External reference
Alcohol-induced changes in opioid peptide levels in adolescent rats are dependent on housing conditions
10.1111/acer.12586 · 2014 · External reference
Sweetened ethanol drinking during social isolation: enhanced intake, resistance to genetic heterogeneity and the emergence of a distinctive drinking pattern in adolescent mice
10.1111/gbb.12346 · 2017 · External reference
Mesolimbic dopaminergic pathways in fear conditioning
10.1016/j.pneurobio.2004.09.004 · 2004 · External reference
Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats
10.1016/j.euroneuro.2010.07.006 · 2011 · External reference
Effects of early social isolation and adolescent single prolonged stress on anxiety-like behaviors and voluntary ethanol consumption in female Long Evans rats
10.1111/acer.15397 · 2024 · External reference
Psychosocial stress and chronic ethanol ingestion in male rats: Effects on elevated plus maze behavior and ultrasonic vocalizations
10.1016/j.physbeh.2008.02.010 · 2008 · External reference
Acute novel stressors modify ethanol intake of psychosocially stressed rats
10.1016/j.pbb.2010.02.017 · 2010 · External reference
Effects of chronic social stress on neuroendocrine responsiveness to challenge with ethanol, dexamethasone and corticotropin-releasing hormone
10.1159/000083682 · 2004 · External reference
Influences of housing conditions and ethanol intake on binding characteristics of D2, S-HTIA, and benzodiazepine receptors of rats. In
10.1016/0091-3057(95)00093-c · 1995 · External reference
Social isolation stress in adolescence, but not adulthood, produces hypersocial behavior in adult male and female C57BL/6J mice
2020 · External reference
Effects of environmental enrichment on voluntary ethanol intake in rats
10.1016/0091-3057(89)90545-5 · 1989 · External reference
Effects of duration and timing of environmental enrichment on voluntary ethanol intake in rats
10.1016/0091-3057(92)90213-y · 1992 · External reference
Dopamine-mediated modulation of odour-evoked amygdala potentials during pavlovian conditioning
10.1038/417282a · 2002 · External reference
Does a relationship exist between the quality of stress and the motivation to ingest alcohol? In Pergamon Alcohol
1994 · External reference
Oral ethanol self-administration in rats: models of alcohol-seeking behavior
10.1111/j.1530-0277.1988.tb00248.x · 1988 · External reference
Voluntary ethanol consumption induced by social isolation reverses the increase of α 4/δ GABA A receptor gene expression and function in the hippocampus of C57BL/6J mice
10.3389/fnins.2011.00015 · 2011 · External reference
10.1016/b978-0-12-385506-0.00010-7
10.1016/b978-0-12-385506-0.00010-7 · External reference
Age-Dependent Effects of Isolation Housing on the Self-Administration of Ethanol in Laboratory Rats
1990 · External reference
Analysis of inflammation
10.1146/annurev.bioeng.8.061505.095708 · 2006 · External reference
Effects of pair housing on voluntary alcohol intake in male and female Wistar rats
10.1016/j.alcohol.2019.12.005 · 2020 · External reference
Tonically active GABAA receptors: Modulating gain and maintaining the tone
10.1016/j.tins.2004.03.005 · 2004 · External reference
Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat
10.1080/10253890500495244 · 2005 · External reference
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain
10.1046/j.1471-4159.2000.0750732.x · 2000 · External reference
Effects of isolation stress and voluntary ethanol exposure during adolescence on ethanol and nicotine co-use in adulthood using male rats
2024 · External reference
Adolescent social isolation increases anxiety-like behavior and ethanol intake and impairs fear extinction in adulthood: Possible role of disrupted noradrenergic signaling
10.1016/j.neuropharm.2015.05.025 · 2015 · External reference
Associations between solitary drinking and increased alcohol consumption, alcohol problems, and drinking to cope motives in adolescents and young adults: a systematic review and meta-analysis
2020 · External reference
Effect of social isolation on ethanol consumption and substance P/neurokinin expression in Wistar rats
10.1016/j.alcohol.2005.07.003 · 2005 · External reference
Effects of Cagemate Gender and the Cagemate’s access to ethanol on ethanol and water intake of the proximal male or the proximal female CD-1 mouse
10.1016/j.alcohol.2013.10.006 · 2014 · External reference
Effects of number of cagemates on home cage ethanol drinking during proximal cagemate drinking (PCD) procedures in male and female CD-1 mice
10.1016/j.pnpbp.2014.10.001 · 2015 · External reference
Isolation stress and chronic mild stress induced immobility in the defensive burying behavior and a transient increased ethanol intake in Wistar rats
10.1016/j.alcohol.2017.03.005 · 2017 · External reference
Sex differences in ethanol intake and sensitivity to aversive effects during adolescence and adulthood
10.1093/alcalc/agp048 · 2009 · External reference
Imaging dopamine’s role in drug abuse and addiction
10.1016/j.neuropharm.2008.05.022 · 2009 · External reference
There and back again: a tale of norepinephrine and drug addiction
10.1038/sj.npp.1301263 · 2007 · External reference
Social deprivation enhances VTA synaptic plasticity and drug-induced contextual learning
10.1016/j.neuron.2012.11.022 · 2013 · External reference
Free choice ethanol intake of laboratory rats under different social conditions. In
1990 · External reference
Social Behavior, Dominance, Social Deprivation of Rats Determine Drug Choice and. In Btochemtstr 3 & Behavtor
1991 · External reference
Adolescent intermittent ethanol drives modest neuroinflammation but does not escalate drinking in male rats
10.3390/cells12212572 · 2023 · External reference
Unresolved reference
External reference
Voluntary ethanol consumption during early social isolation and responding for ethanol in adulthood
10.1016/j.alcohol.2018.09.004 · 2019 · External reference
Social isolation and the brain: effects and mechanisms
2023 · External reference
Accelerated acquisition of ethanol tolerance in isolated mice
1982 · External reference
Brain default-mode network dysfunction in addiction
2019 · External reference
