Research graph
References from Synucleins deficiency alter dopamine- and glutamate-induced calcium signal in neurons and astrocytes. Local targets link to admitted publications; unresolved targets remain external evidence.
Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice
10.1016/j.neurobiolaging.2008.11.001 · 2010 · External reference
Isolating brain mitochondria by differential centrifugation
2016 · External reference
Alpha-synuclein and beta-amyloid – different targets, same players: calcium, free radicals and mitochondria in the mechanism of neurodegeneration
10.1016/j.bbrc.2016.07.103 · 2017 · External reference
α-synuclein fibrils per se but not α-synuclein seeded aggregation causes mitochondrial dysfunction and cell death in human neurons
10.1016/j.redox.2025.103817 · 2025 · External reference
Ca2+ is a key factor in α-synuclein-induced neurotoxicity
10.1242/jcs.180737 · 2016 · External reference
Functional alterations to the nigrostriatal System in mice lacking all three members of the Synuclein family
10.1523/jneurosci.6194-10.2011 · 2011 · External reference
Ecdysterone prevents negative effect of acute immobilization stress on energy metabolism of rat liver mitochondria
10.1016/j.jsbmb.2022.106066 · 2022 · External reference
Dopamine controls neuronal spontaneous calcium oscillations via astrocytic signal
10.1016/j.ceca.2021.102359 · 2021 · External reference
α-Synuclein promotes SNARE-Complex assembly in vivo and in vitro
10.1126/science.1195227 · 2010 · External reference
α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction
10.1126/sciadv.ady6978 · 2026 · External reference
Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism
10.1016/j.neurobiolaging.2016.06.020 · 2016 · External reference
Direct observation of the interconversion of normal and toxic forms of α-Synuclein
10.1016/j.cell.2012.03.037 · 2012 · External reference
Targeting dopaminergic pathways: current and emerging dopamine inhibitors in neurological and psychiatric disorders
10.2174/0118715273431536251202114957 · 2026 · External reference
Lack of synucleins induces an alteration of lipid peroxidation in the brain
10.1016/j.bbrc.2026.154420 · 2026 · External reference
Alpha- and gamma-synucleins regulate energy metabolism and Xanthine oxidase activity in brain cells
10.1134/s0006297925602278 · 2025 · External reference
Dopamine-1-mediated stimulation of phospholipase C activity in rat renal cortical membranes
10.1016/s0021-9258(18)81855-5 · 1989 · External reference
Role of α-synuclein in synaptic glutamate release
10.1016/j.nbd.2007.06.016 · 2007 · External reference
Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors
10.1038/nn.2592 · 2010 · External reference
Acute CCl4-induced intoxication reduces complex I, but not complex II-based mitochondrial bioenergetics – protective role of succinate
10.1007/s10863-024-10047-6 · 2025 · External reference
Synaptic changes in mice lacking Alpha- and gamma-synucleins
10.3390/biomedicines13122866 · 2025 · External reference
Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal
10.1074/jbc.m401923200 · 2004 · External reference
Monomeric Alpha-Synuclein exerts a physiological role on brain ATP synthase
10.1523/jneurosci.1659-16.2016 · 2016 · External reference
Alpha-synuclein is involved in manganese-induced spatial memory and synaptic plasticity impairments via TrkB/Akt/Fyn-mediated phosphorylation of NMDA receptors
10.1038/s41419-020-03051-2 · 2020 · External reference
β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
10.1016/j.jbc.2021.101375 · 2021 · External reference
Adrenaline induces calcium signal in astrocytes and vasoconstriction via activation of monoamine oxidase
10.1016/j.freeradbiomed.2020.07.011 · 2020 · External reference
Nrf2 modulates cytosolic and mitochondrial calcium signal
10.1016/j.redox.2026.104213 · 2026 · External reference
Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ‐synuclein, α‐synuclein and double α/γ‐synuclein null mutant mice
10.1111/j.1471-4159.2004.02378.x · 2004 · External reference
Distinct properties of Ca2+ efflux from brain, heart and liver mitochondria: the effects of Na+, Li+ and the mitochondrial Na+/Ca2+ exchange inhibitor CGP37157
10.1016/j.ceca.2021.102382 · 2021 · External reference
Nuclear calcium signaling in D1 receptor–expressing neurons of the nucleus accumbens regulates molecular, cellular, and behavioral adaptations to cocaine
10.1016/j.biopsych.2025.01.013 · 2025 · External reference
Distinct role of γ-Synuclein in the regulation of motor performance and behavioral responses in mice
10.3390/biomedicines14010092 · 2026 · External reference
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
10.1016/0896-6273(95)90294-5 · 1995 · External reference
Dopamine induces Ca2+ signaling in astrocytes through reactive oxygen species generated by monoamine oxidase
10.1074/jbc.m110.111450 · 2010 · External reference
Novel pathway for an old neurotransmitter: Dopamine-induced neuronal calcium signalling via receptor-independent mechanisms
10.1016/j.ceca.2010.08.008 · 2010 · External reference
Dopamine protects neurons against glutamate-induced excitotoxicity
10.1038/cddis.2012.194 · 2013 · External reference
α-Synuclein and dopamine at the crossroads of Parkinson's disease
10.1016/j.tins.2010.09.004 · 2010 · External reference
Loss of the Synuclein family members differentially affects Baseline- and apomorphine-associated EEG determinants in Single-, Double- and triple-knockout mice
10.3390/biomedicines10123128 · 2022 · External reference
Regulation of NMDA receptors by dopamine D 4 signaling in prefrontal cortex
10.1523/jneurosci.23-30-09852.2003 · 2003 · External reference
