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References from Varlitinib attenuates neuroinflammation and dopaminergic neurodegeneration in experimental Parkinsonism. Local targets link to admitted publications; unresolved targets remain external evidence.
Neurodegeneration in Parkinson’s disease: are we looking at the right spot?
10.1186/s13041-025-01218-6 · 2025 · External reference
10.1002/9781444341256.ch21
10.1002/9781444341256.ch21 · External reference
Parkinson's disease: mechanisms and models
10.1016/s0896-6273(03)00568-3 · 2003 · External reference
Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease
10.1002/mds.27874 · 2020 · External reference
Role of NLRP3 inflammasome in Parkinson’s disease and therapeutic considerations
10.3233/jpd-223290 · 2022 · External reference
Development of EGFR family small molecule inhibitors for anticancer intervention: an overview of approved drugs and clinical candidates
10.2174/0929867321666140915142809 · 2014 · External reference
Varlitinib and paclitaxel for EGFR/HER2 co-expressing advanced gastric cancer: a multicenter phase Ib/II study (K-MASTER-13)
10.4143/crt.2023.1324 · 2024 · External reference
Inhibiting EGFR/HER-2 ameliorates neuroinflammatory responses and the early stage of tau pathology through DYRK1A
10.3389/fimmu.2022.903309 · 2022 · External reference
Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson’s disease model
10.1186/s12974-025-03461-z · 2025 · External reference
Juglans mandshurica leaf extract protects skin fibroblasts from damage by regulating the oxidative defense system
10.1016/j.bbrc.2012.04.013 · 2012 · External reference
Inhibitory effects of myricetin on lipopolysaccharide-induced neuroinflammation
10.3390/brainsci10010032 · 2020 · External reference
Resilin, an insect-derived elastomeric protein, protects dopaminergic neurons in Parkinson disease models
10.1016/j.neulet.2022.136667 · 2022 · External reference
Artemisinin protects dopaminergic neurons against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced neurotoxicity in a mouse model of Parkinson’s disease
10.1016/j.biopha.2023.115972 · 2024 · External reference
The insect molting hormone 20-hydroxyecdysone protects dopaminergic neurons against MPTP-induced neurotoxicity in a mouse model of Parkinson's disease
10.1016/j.freeradbiomed.2020.07.010 · 2020 · External reference
Targeting HER2-positive breast cancer: advances and future directions
10.1038/s41573-022-00579-0 · 2023 · External reference
Alpha-synuclein/MPP+ mediated activation of NLRP3 inflammasome through microtubule-driven mitochondrial perinuclear transport
10.1016/j.bbrc.2022.01.047 · 2022 · External reference
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
10.1038/nm.3806 · 2015 · External reference
Drug repurposing as an effective drug discovery strategy: a critical review
10.2147/dddt.s576701 · 2025 · External reference
Drug repurposing: progress, challenges and recommendations
10.1038/nrd.2018.168 · 2019 · External reference