Research graph
References from Cytochrome P450 Expression Influences Behavioral Responses to 3,3ʹ-Dichlorobiphenyl (PCB 11) in Juvenile Male and Female Mice Exposed Throughout Gestation and Lactation. Local targets link to admitted publications; unresolved targets remain external evidence.
Concentrations of polychlorinated biphenyl in indoor environment of public bars and its health implications
10.1007/s10661-021-09405-3 · 2021 · External reference
Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models of cdkl5 deficiency
10.1093/hmg/ddac091 · 2022 · External reference
Inhalation and dietary exposure to pcbs in urban and rural cohorts via congener-specific measurements
10.1021/es5048039 · 2015 · External reference
Concentration levels and congener profiles of polychlorinated biphenyls, pentachlorobenzene, and hexachlorobenzene in commercial pigments
10.1007/s11356-013-1977-2 · 2014 · External reference
Polychlorinated dioxins, furans (pcdd/fs) and dioxin-like polychlorinated biphenyls (dl-pcbs) in food from italy: Estimates of dietaryintake and assessment
10.1111/1750-3841.15901 · 2021 · External reference
Sex differences in effects of gestational polychlorinated biphenyl exposure on hypothalamic neuroimmune and neuromodulator systems in neonatal rats
10.1016/j.taap.2018.06.002 · 2018 · External reference
Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 1. Sexually dimorphic effects on social and anxiety-like behaviors
10.1016/j.yhbeh.2015.11.007 · 2016 · External reference
Developmental social communication deficits in the shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder
10.1002/aur.1925 · 2018 · External reference
Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats
10.1038/s41398-020-00978-0 · 2020 · External reference
A scoping review of neurotoxic and behavioral outcomes following polychlorinated biphenyl (pcb) exposure in post-weaned rodents
10.3390/ijms262210829 · 2025 · External reference
Autism-relevant social abnormalities and cognitive deficits in engrailed-2 knockout mice
10.1371/journal.pone.0040914 · 2012 · External reference
Assessing reproductive status/stages in mice
10.1002/0471142301.nsa04is48 · 2009 · External reference
Quantification of polychlorinated biphenyls and polybrominated diphenyl ethers in commercial cows' milk from california by gas chromatography-triple quadruple mass spectrometry
2017 · External reference
Ahr and cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls
10.1016/j.neuro.2018.01.008 · 2018 · External reference
Ahrd cyp1a2(-/-) mice show increased susceptibility to pcb-induced developmental neurotoxicity
10.1016/j.neuro.2012.08.005 · 2012 · External reference
utero and lactational exposure to pcbs in mice: Adult offspring show altered learning and memory depending on cyp1a2 and ahr genotypes. Environ Health Persp. 119
2011 · External reference
utero and lactational exposure to a complex mixture of polychlorinated biphenyls: Toxicity in pups dependent on the cyp1a2 and ahr genotypes
10.1093/toxsci/kfq314 · 2011 · External reference
Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (pcb3) in female rats
10.1021/tx500150h · 2014 · External reference
Pesticides and polychlorinated biphenyls in milk and dairy products in croatia: A health risk assessment
10.3390/foods13081155 · 2024 · External reference
Differential prevalence of pfas, pcbs and pesticides in liver of hunted game
10.1007/s11356-026-37805-w · 2026 · External reference
Metabolism and metabolites of polychlorinated biphenyls
10.3109/10408444.2014.999365 · 2015 · External reference
Identification of a sulfate metabolite of pcb 11 in human serum
10.1016/j.envint.2016.10.023 · 2017 · External reference
Human prenatal and postnatal exposure to polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorobiphenylols, and pentachlorophenol
10.1289/ehp.5946 · 2003 · External reference
Long-term outcomes of adhd: A systematic review of self-esteem and social function
10.1177/1087054713486516 · 2016 · External reference
Polychlorinated biphenyls (pcbs) and organochlorine pesticides (ocps) in water-sediment system of southern mediterranean: Concentration, source and ecological risk assessment
10.1016/j.marpolbul.2023.115692 · 2023 · External reference
Emissions of tetrachlorobiphenyls (pcbs 47, 51, and 68) from polymer resin on kitchen cabinets as a non-aroclor source to residential air
10.1021/acs.est.8b00966 · 2018 · External reference
An extended structure-activity relationship of nondioxin-like pcbs evaluates and supports modeling predictions and identifies picomolar potency of pcb 202 towards ryanodine receptors
10.1093/toxsci/kfw189 · 2017 · External reference
Persistent organic pollutant concentrations in human pancreas correlate with markers of beta cell dysfunction
10.1038/s41467-026-71847-5 · 2026 · External reference
Inadvertent polychlorinated biphenyls in commercial paint pigments
10.1021/es902413k · 2010 · External reference
The fate of inhaled (14)c-labeled pcb11 and its metabolites in vivo
10.1016/j.envint.2013.10.017 · 2014 · External reference
Elimination of inhaled 3,3'-dichlorobiphenyl and the formation of the 4-hydroxylated metabolite
10.1021/es3049114 · 2013 · External reference
Widespread emissions of polychlorinated biphenyls from building materials in vermont schools
2026 · External reference
Distinguishing aroclor and non-aroclor sources to chicago air
10.1016/j.scitotenv.2022.153263 · 2022 · External reference
Perinatal exposure to polychlorinated biphenyls alters social behaviors in rats
10.1016/j.toxlet.2010.08.015 · 2010 · External reference
Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome p-450
10.1021/bi00529a009 · 1981 · External reference
Toxicokinetics of chiral polychlorinated biphenyls across different species--a review
10.1007/s11356-015-4383-0 · 2016 · External reference
Editor's highlight: Congener-specific disposition of chiral polychlorinated biphenyls in lactating mice and their offspring: Implications for pcb developmental neurotoxicity
10.1093/toxsci/kfx071 · 2017 · External reference
Sex-dependent effects of 2,2',3,5',6-pentachlorobiphenyl on dendritic arborization of primary mouse neurons
10.1093/toxsci/kfy277 · 2019 · External reference
Sex and genotype modulate the dendritic effects of developmental exposure to a human-relevant polychlorinated biphenyls mixture in the juvenile mouse
10.3389/fnins.2021.766802 · 2021 · External reference
Social decision making in autism: On the impact of mirror neurons, motor control, and imitative behaviors
10.1111/cns.13001 · 2018 · External reference
Social behavior in prepubertal neurexin 1α deficient rats: A model of neurodevelopmental disorders
10.1037/bne0000482 · 2021 · External reference
Improving bioscience research reporting: The arrive guidelines for reporting animal research
10.1111/j.1939-165x.2012.00418.x · 2012 · External reference
Genetic differences in the aryl hydrocarbon receptor and cyp1a2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: Relevance to studies of human neurological disorders
10.1007/s00335-017-9728-1 · 2018 · External reference
Evidence implicating non-dioxin-like congeners as the key mediators of polychlorinated biphenyl (pcb) developmental neurotoxicity
10.3390/ijms21031013 · 2020 · External reference
The developmental neurotoxicity of legacy vs. Contemporary polychlorinated biphenyls (pcbs): Similarities and differences
2019 · External reference
The developmental neurotoxicity of legacy vs. Contemporary polychlorinated biphenyls (pcbs): Similarities and differences
10.1007/s11356-019-06723-5 · 2020 · External reference
Tissue levels of persistent organic pollutants and biotransformation enzyme polymorphisms in human stomach cancer
2026 · External reference
Hydroxylated polychlorinated biphenyls in human sera from adolescents and their mothers living in two u.S. Midwestern communities
10.1016/j.chemosphere.2015.12.113 · 2016 · External reference
Human serum from urban and rural adolescents and their mothers shows exposure to polychlorinated biphenyls not found in commercial mixtures
10.1021/acs.est.5b01854 · 2015 · External reference
Formulation and characterization of an experimental pcb mixture designed to mimic human exposure from contaminated fish
10.1093/toxsci/kfi338 · 2005 · External reference
The y-maze for assessment of spatial working and reference memory in mice
10.1007/978-1-4939-8994-2_10 · 2019 · External reference
Effects of polychlorinated biphenyl (pcb) exposure on response perseveration and ultrasonic vocalization emission in rat during development
10.4161/23273739.2014.969608 · 2014 · External reference
The dendritic tree and brain disorders
10.1016/j.mcn.2012.03.005 · 2012 · External reference
Identification of cytochrome p450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (nnk): Insights from a novel cyp2abfgs-null mouse
10.1093/carcin/bgu182 · 2014 · External reference
Elucidating the metabolism of chiral pcb95 in wildtype and transgenic mouse models with altered cytochrome p450 enzymes using intestinal content screening
10.1021/acs.chemrestox.4c00350 · 2024 · External reference
Assessment of polychlorinated biphenyls and their hydroxylated metabolites in postmortem human brain samples: Age and brain region differences
10.1021/acs.est.2c00581 · 2022 · External reference
Sex-specific effects of developmental exposure to polychlorinated biphenyls on neuroimmune and dopaminergic endpoints in adolescent rats
10.1016/j.ntt.2020.106880 · 2020 · External reference
Variability in pcb and oh-pcb serum levels in children and their mothers in urban and rural u.S. Communities
10.1021/es502490w · 2014 · External reference
Airborne pcbs and oh-pcbs inside and outside urban and rural u.S. Schools
10.1021/acs.est.7b01910 · 2017 · External reference
Is current generation of polychlorinated biphenyls exceeding peak production of the 1970s?
10.1016/j.scitotenv.2024.171436 · 2024 · External reference
Human cyp2d6 varies across the estrous cycle in brains of transgenic mice altering drug response
10.1016/j.pnpbp.2024.111108 · 2024 · External reference
Studies on the structure-activity relationships for the metabolism of polybrominated biphenyls by rat liver microsomes
10.1016/0041-008x(85)90309-6 · 1985 · External reference
Sociability and preference for social novelty in five inbred strains: An approach to assess autistic-like behavior in mice
10.1111/j.1601-1848.2004.00076.x · 2004 · External reference
A review of polychlorinated biphenyls (pcbs) pollution in the air: Where and how much are we exposed to?
10.3390/ijerph192113923 · 2022 · External reference
Polychlorinated biphenyl (pcb) concentrations and breakpoint trends across the waters of the great lakes by isotope-dilution high-resolution mass spectroscopy
10.1016/j.scitotenv.2024.178024 · 2025 · External reference
Exposure to hydroxylated polychlorinated biphenyls (oh-pcbs) in the prenatal period and subsequent neurodevelopment in eastern slovakia
10.1289/ehp.0900611 · 2009 · External reference
Neurotoxicity of polychlorinated biphenyls and related organohalogens
10.1007/s00401-019-01978-1 · 2019 · External reference
Early adversity alters neurodevelopmental milestones in male and female rat pups and motor cortex morphology and gait in juveniles
10.1016/j.ynstr.2026.100814 · 2026 · External reference
Polymorphic cytochrome p450 enzymes (cyps) and their role in personalized therapy
10.1371/journal.pone.0082562 · 2013 · External reference
Ultrasonic vocalizations in mice: Relevance for ethologic and neurodevelopmental disorders studies
10.4103/1673-5374.300340 · 2021 · External reference
A global, cross-system meta-analysis of polychlorinated biphenyl biomagnification
10.1021/acs.est.9b07693 · 2020 · External reference
Embryonic exposure to 2,2',3,5',6-pentachlorobiphenyl (pcb-95) causes developmental malformations in zebrafish
10.1002/etc.4587 · 2020 · External reference
The effects of prenatal pcbs on adult social behavior in rats
10.1016/j.yhbeh.2015.06.002 · 2015 · External reference
Analysis of within subjects variability in mouse ultrasonic vocalization: Pups exhibit inconsistent, state-like patterns of call production
10.3389/fnbeh.2016.00182 · 2016 · External reference
3,3'-dichlorobiphenyl (pcb 11) alters the hepatic expression of cytochrome p450 enzymes in the liver of mouse dams exposed orally during pregnancy and lactation
10.1007/s00204-025-04241-7 · 2026 · External reference
Polychlorinated biphenyls in food
10.1021/acs.est.0c03632 · 2020 · External reference
Unusual repertoire of vocalizations in the btbr t+tf/j mouse model of autism
10.1371/journal.pone.0003067 · 2008 · External reference
Identifying small molecules via high resolution mass spectrometry: Communicating confidence
2014 · External reference
Detection of 3,3'-dichlorobiphenyl in human maternal plasma and its effects on axonal and dendritic growth in primary rat neurons
10.1093/toxsci/kfx100 · 2017 · External reference
3,3'-dichlorobiphenyl (pcb 11) promotes dendritic arborization in primary rat cortical neurons via a creb-dependent mechanism
10.1007/s00204-018-2307-8 · 2018 · External reference
Developmental exposure to a human-relevant polychlorinated biphenyl mixture causes behavioral phenotypes that vary by sex and genotype in juvenile mice expressing human mutations that modulate neuronal calcium
10.3389/fnins.2021.766826 · 2021 · External reference
Comparative analyses of the 12 most abundant pcb congeners detected in human maternal serum for activity at the thyroid hormone receptor and ryanodine receptor
10.1021/acs.est.9b00535 · 2019 · External reference
Neonatal transitions in social behavior and their implications for autism
10.1016/j.tics.2018.02.012 · 2018 · External reference
Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: Opportunities for translation
10.1097/wco.0000000000000537 · 2018 · External reference
Behavioural phenotyping assays for mouse models of autism
10.1038/nrn2851 · 2010 · External reference
Offspring neuroimmune consequences of maternal malnutrition: Potential mechanism for behavioral impairments that underlie metabolic and neurodevelopmental disorders
10.1016/j.yfrne.2017.07.007 · 2017 · External reference
Fetal exposure to pcbs and their hydroxylated metabolites in a dutch cohort
10.1289/ehp.6424 · 2004 · External reference
Human cyp2a6, cyp2b6, and cyp2e1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
10.1021/acs.est.8b05250 · 2019 · External reference
Microglial responses to inflammatory challenge in adult rats altered by developmental exposure to polychlorinated biphenyls in a sex-specific manner
10.1016/j.neuro.2024.07.009 · 2024 · External reference
Neurodevelopmental outcomes relevant to autism in juvenile mice exposed to pcb 11 in the maternal diet throughout gestation and lactation
10.3389/ftox.2026.1816944 · 2026 · External reference
Developmental exposure to the fox river pcb mixture modulates behavior in juvenile mice
10.1016/j.neuro.2024.06.008 · 2024 · External reference
3,3′-dichlorobiphenyl is metabolized to a complex mixture of oxidative metabolites, including novel methoxylated metabolites, by hepg2 cells
10.1021/acs.est.0c03476 · 2020 · External reference
Disposition of pcb 11 in mice following acute oral exposure
10.1021/acs.chemrestox.1c00067 · 2021 · External reference
Generation and characterization of a transgenic mouse model with hepatic expression of human cyp2a6
10.1016/j.bbrc.2005.08.086 · 2005 · External reference
Cytochrome p450 enzymes and drug metabolism in humans
10.3390/ijms222312808 · 2021 · External reference