Research graph
References from Purinergic receptor activation rectifies autism-associated endothelial dysfunction. Local targets link to admitted publications; unresolved targets remain external evidence.
Brain Energy and Oxygen Metabolism: Emerging Role in Normal Function and Disease
10.3389/fnmol.2018.00216 · 2018 · External reference
Brain Fuel Utilization in the Developing Brain
10.1159/000508054 · 2019 · External reference
Vulnerability of the developing brain to hypoxic-ischemic damage: contribution of the cerebral vasculature to injury and repair?
10.3389/fphys.2012.00424 · 2012 · External reference
Vascular Regulation of Developmental Neurogenesis
10.3389/fcell.2022.890852 · 2022 · External reference
From Neurodevelopmental to Neurodegenerative Disorders: The Vascular Continuum
10.3389/fnagi.2021.749026 · 2021 · External reference
Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice
10.1038/s41593-020-0663-1 · 2020 · External reference
16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
10.1016/j.celrep.2023.112485 · 2023 · External reference
A Vascular-Centric Approach to Autism Spectrum Disorders
10.1177/26331055241235921 · 2024 · External reference
Autism spectrum disorders: Integration of the genome, transcriptome and the environment
10.1016/j.jns.2016.03.026 · 2016 · External reference
A Short Review on the Current Understanding of Autism Spectrum Disorders
10.5607/en.2016.25.1.1 · 2016 · External reference
EEG Analytics for Early Detection of Autism Spectrum Disorder: A data-driven approach
10.1038/s41598-018-24318-x · 2018 · External reference
Neural Hyperexcitability in Autism Spectrum Disorders
10.3390/brainsci7100129 · 2017 · External reference
Neuron Number and Size in Prefrontal Cortex of Children With Autism
10.1001/jama.2011.1638 · 2011 · External reference
Prenatal Neurogenesis in Autism Spectrum Disorders
10.3389/fchem.2016.00012 · 2016 · External reference
The neuroanatomy of autism - a developmental perspective
10.1111/joa.12542 · 2017 · External reference
Isolation and functional characterization of primary endothelial cells from mouse cerebral cortex
10.1016/j.xpro.2021.101019 · 2021 · External reference
Sensory-Related Neural Activity Regulates the Structure of Vascular Networks in the Cerebral Cortex
10.1016/j.neuron.2014.07.034 · 2014 · External reference
Measurement of Oxidized/Reduced Glutathione Ratio
10.1007/978-1-60761-756-3_18 · 2010 · External reference
The role of glutathione redox imbalance in autism spectrum disorder: A review
10.1016/j.freeradbiomed.2020.07.017 · 2020 · External reference
AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease
10.1111/joim.12268 · 2014 · External reference
Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio
10.1038/ncomms3550 · 2013 · External reference
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo
10.7554/elife.56006 · 2020 · External reference
A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System
10.1038/s44161-022-00046-4 · 2022 · External reference
Mitochondrial ATP Production is Required for Endothelial Cell Control of Vascular Tone
2023 · External reference
Lipidoid nanoparticles increase ATP uptake into hypoxic brain endothelial cells
10.1016/j.ejpb.2022.10.011 · 2022 · External reference
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
10.1016/j.jconrel.2016.05.059 · 2016 · External reference
Lipid Nanoparticle Systems for Enabling Gene Therapies
10.1016/j.ymthe.2017.03.013 · 2017 · External reference
Mechanisms of ATP release and signalling in the blood vessel wall
10.1093/cvr/cvs187 · 2012 · External reference
Purinergic signaling: A gatekeeper of blood-brain barrier permeation
2023 · External reference
Brain endothelial cell TRPA1 channels initiate neurovascular coupling
10.7554/elife.63040 · 2021 · External reference
Site-specific and developmental expression of pannexin1 in the mouse nervous system
10.1111/j.1460-9568.2005.04139.x · 2005 · External reference
Purinergic P2Y2 receptors modulate endothelial sprouting
10.1007/s00018-019-03213-2 · 2020 · External reference
Purine receptors and Ca2+ signalling in the human blood-brain barrier endothelial cell line hCMEC/D3
10.1007/s11302-011-9262-7 · 2012 · External reference
Neuromodulation by extracellular ATP and P2X receptors in the CNS
10.1016/j.neuron.2012.09.024 · 2012 · External reference
Prevention of Surgery-Induced Dry Eye by Diquafosol Eyedrops after Femtosecond Laser-Assisted Cataract Surgery
10.3390/jcm11195757 · 2022 · External reference
A randomised, prospective study of the effects of 3% diquafosol on ocular surface following cataract surgery
2021 · External reference
3-Nitrotyrosine: a versatile oxidative stress biomarker for major neurodegenerative diseases
10.1080/00207454.2020.1713776 · 2020 · External reference
Hyperactivity and male-specific sleep deficits in the 16p11.2 deletion mouse model of autism
10.1002/aur.1707 · 2017 · External reference
Untargeted Metabolomics for Autism Spectrum Disorders: Current Status and Future Directions
10.3389/fpsyt.2019.00647 · 2019 · External reference
Profiles of urine and blood metabolomics in autism spectrum disorders
10.1007/s11011-021-00788-3 · 2021 · External reference
Metabolic network analysis of pre-ASD newborns and 5-year-old children with autism spectrum disorder
10.1038/s42003-024-06102-y · 2024 · External reference
The multifaceted role of mitochondria in autism spectrum disorder
10.1038/s41380-024-02725-z · 2025 · External reference
Mitochondrial transfer mediates endothelial cell engraftment through mitophagy
10.1038/s41586-024-07340-0 · 2024 · External reference
Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks
10.1016/j.bbadis.2018.03.001 · 2018 · External reference
Purinergic signaling and blood vessels in health and disease
10.1124/pr.113.008029 · 2014 · External reference
P2Y2 and Gq/G11 control blood pressure by mediating endothelial mechanotransduction
10.1172/jci81067 · 2015 · External reference
Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11.2 deletion female mice
10.1038/s41380-024-02596-4 · 2024 · External reference
Inhibition of purinergic P2 receptors prevents synaptic and behavioral alterations in a rodent model of autism spectrum disorders
10.1016/j.rasd.2024.102353 · 2024 · External reference
Disruption of the ATP/adenosine balance in CD39−/− mice is associated with handling-induced seizures
10.1111/imm.12798 · 2017 · External reference
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39
2025 · External reference
Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism
10.1073/pnas.1114042108 · 2011 · External reference
Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes
10.1038/nmeth.2773 · 2014 · External reference
MetaboAnalyst: a web server for metabolomic data analysis and interpretation
10.1093/nar/gkp356 · 2009 · External reference
Unresolved reference
External reference
The slice overlay assay: a versatile tool to study the influence of extracellular signals on neuronal development
10.1126/stke.2002.136.pl9 · 2002 · External reference
Feature detection with automatic scale selection
10.1023/a:1008045108935 · 1998 · External reference
Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation
10.1038/s41467-023-40682-3 · 2023 · External reference
Exploration of Nitrotyrosine-Containing Proteins and Peptides by Antibody-Based Enrichment Strategies
10.1016/j.mcpro.2024.100733 · 2024 · External reference
Extracellular Vesicles Derived from a Human Brain Endothelial Cell Line Increase Cellular ATP Levels
10.1208/s12249-020-01892-w · 2021 · External reference
Engineering Extracellular Vesicles to Modulate Their Innate Mitochondrial Load
10.1007/s12195-022-00738-8 · 2022 · External reference
Mitochondria-containing extracellular vesicles (EV) reduce mouse brain infarct sizes and EV/HSP27 protect ischemic brain endothelial cultures
10.1016/j.jconrel.2023.01.025 · 2023 · External reference
Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells
10.1016/j.jconrel.2021.08.038 · 2021 · External reference
Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy
10.1016/j.jconrel.2024.07.065 · 2024 · External reference
Mitochondria-containing large extracellular vesicles target mouse motor neurons upon intramuscular injection
10.1016/j.vesic.2025.100100 · 2026 · External reference
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
10.1038/ncomms5277 · 2014 · External reference
Tracking neuronal migration in adult brain slices
2015 · External reference
In vivo deep two-photon imaging of neural circuits with the fluorescent Ca2+ indicator Cal-590
10.1113/jp272790 · 2017 · External reference
Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein
10.1007/s12015-020-10056-z · 2021 · External reference
Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics
10.1016/j.cell.2020.12.026 · 2021 · External reference
CaMKIIalpha Expression Defines Two Functionally Distinct Populations of Granule Cells Involved in Different Types of Odor Behavior
10.1016/j.cub.2017.09.058 · 2017 · External reference
Use of the Open Field Maze to measure locomotor and anxiety-like behavior in mice
2015 · External reference
