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References from Comparative analysis of the effects of Δ9-tetrahydrocannabinol and cannabidiol on pilocarpine-induced status epilepticus in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Interactions between cannabidiol and Δ9-tetrahydrocannabinol in modulating seizure susceptibility and survival in a mouse model of Dravet syndrome
10.1111/bph.15181 · 2020 · External reference
Unbalanced inhibitory/excitatory responses in the substantia nigra pars reticulata underlie cannabinoid-related slowness of movements
10.1523/jneurosci.0045-20.2020 · 2020 · External reference
Evaluation of the possible anticonvulsant effect of Δ9-tetrahydrocannabinolic acid in murine seizure models
10.1089/can.2020.0073 · 2022 · External reference
Chronux: a platform for analyzing neural signals
10.1016/j.jneumeth.2010.06.020 · 2010 · External reference
Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity
10.1046/j.1460-9568.2003.02588.x · 2003 · External reference
Synergistic action of CB 1 and 5-HT 2B receptors in preventing pilocarpine-induced status epilepticus in rats
10.1016/j.nbd.2019.01.026 · 2019 · External reference
2-AG-mediated control of GABAergic signaling is impaired in a model of epilepsy
10.1523/jneurosci.0541-22.2022 · 2023 · External reference
Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants
10.7554/elife.06513 · 2015 · External reference
Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus
10.1523/jneurosci.23-06-02371.2003 · 2003 · External reference
Trial of cannabidiol for drug-resistant seizures in the dravet syndrome
10.1056/nejmoa1611618 · 2017 · External reference
Protective effects of cannabidiol against seizures and neuronal death in a rat model of mesial temporal lobe epilepsy
2017 · External reference
The proposed mechanisms of action of CBD in epilepsy
10.1684/epd.2020.1135 · 2020 · External reference
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice
10.1172/jci130419 · 2019 · External reference
The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels
10.1213/00000539-200202000-00015 · 2002 · External reference
Epigenetics and epilepsy
2015 · External reference
Cannabinoid receptor localization in brain
10.1073/pnas.87.5.1932 · 1990 · External reference
Cannabidiol attenuates seizures and social deficits in a mouse model of dravet syndrome
10.1073/pnas.1711351114 · 2017 · External reference
Definition of drug resistant epilepsy: consensus proposal by the ad hoc task force of the ILAE commission on therapeutic strategies
10.1111/j.1528-1167.2009.02397.x · 2010 · External reference
The pilocarpine model of mesial temporal lobe epilepsy: over one decade later, with more rodent species and new investigative approaches
10.1016/j.neubiorev.2021.08.020 · 2021 · External reference
Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice
10.1016/j.nbd.2022.105637 · 2022 · External reference
Termination of acute stress response by the endocannabinoid system is regulated through lysine-specific demethylase 1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL
10.1111/jnc.15000 · 2020 · External reference
Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options
10.1124/pr.120.019539 · 2020 · External reference
Natural (Δ9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor
10.1038/s41598-017-10447-2 · 2017 · External reference
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
10.1126/science.1088208 · 2003 · External reference
Pilocarpine-induced seizures associate with modifications of LSD1/CoREST/HDAC1/2 epigenetic complex and repressive chromatin in mice hippocampus
2021 · External reference
Adjunctive transdermal cannabidiol for adults with focal epilepsy: a randomized clinical trial
10.1001/jamanetworkopen.2022.20189 · 2022 · External reference
Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models
10.1111/epi.14629 · 2019 · External reference
Pilocarpine-induced status epilepticus in mice: a comparison of spectral analysis of electroencephalogram and behavioral grading using the Racine scale
10.1016/j.eplepsyres.2015.09.008 · 2015 · External reference
Modification of seizure activity by electrical stimulation: II
10.1016/0013-4694(72)90177-0 · 1972 · External reference
Beneficial outcome of urethane treatment following status epilepticus in a rat organophosphorus toxicity model
10.1523/eneuro.0070-18.2018 · 2018 · External reference
LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior
10.1073/pnas.1511974113 · 2016 · External reference
NeuroLSD1: splicing-generated epigenetic enhancer of neuroplasticity
10.1016/j.tins.2016.11.002 · 2017 · External reference
LSD1 neurospecific alternative splicing controls neuronal excitability in mouse models of epilepsy
10.1093/cercor/bhu070 · 2015 · External reference
Kainic acid, bicuculline, pentylenetetrazol and pilocarpine elicit maximal dentate activation in the anesthetized rat
10.1016/0920-1211(94)90029-9 · 1994 · External reference
Endocannabinoid-mediated control of neural circuit excitability and epileptic seizures
10.3389/fncir.2021.781113 · 2022 · External reference
Incidence and prevalence of drug-resistant epilepsy: a systematic review and meta-analysis
10.1212/wnl.0000000000011839 · 2021 · External reference
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial
10.1016/s0140-6736(18)30136-3 · 2018 · External reference
Epilepsy in adults
10.1016/s0140-6736(18)32596-0 · 2019 · External reference
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
10.1016/s0306-4522(97)00436-3 · 1998 · External reference
Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats
10.1186/s12987-024-00508-w · 2024 · External reference
Anticonvulsant effect of cannabidiol in the pentylenetetrazole model: pharmacological mechanisms, electroencephalographic profile, and brain cytokine levels
10.1016/j.yebeh.2017.07.014 · 2017 · External reference
LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control
10.1038/nn.4069 · 2015 · External reference
Advances and challenges of cannabidiol as an anti-seizure strategy: preclinical evidence
10.3390/ijms232416181 · 2022 · External reference
Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system
10.1523/jneurosci.5500-09.2010 · 2010 · External reference
