Research graph
References from Electroconvulsive therapy shifting brain dynamics toward more adaptive and integrated states in treatment-resistant depression based on a hidden markov model. Local targets link to admitted publications; unresolved targets remain external evidence.
The definition and meaning of treatment-resistant depression
2001 · External reference
Synthesizing the evidence for ketamine and esketamine in treatment-resistant depression: an international expert opinion on the available evidence and implementation
10.1176/appi.ajp.2020.20081251 · 2021 · External reference
Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions
10.1002/wps.21120 · 2023 · External reference
Treatment-resistant depression and suicidality
10.1016/j.jad.2018.04.016 · 2018 · External reference
A review of the clinical, economic, and societal burden of treatment-resistant depression: 1996–2013
10.1176/appi.ps.201300059 · 2014 · External reference
The burden of treatment-resistant depression: a systematic review of the economic and quality of life literature
10.1016/j.jad.2018.06.045 · 2019 · External reference
Modulation of limbic and prefrontal connectivity by electroconvulsive therapy in treatment-resistant depression: a preliminary study
10.1016/j.brs.2015.08.016 · 2016 · External reference
Default mode network coherence in treatment-resistant major depressive disorder during electroconvulsive therapy
10.1016/j.jad.2016.06.059 · 2016 · External reference
A multimetric systematic review of fMRI findings in patients with MDD receiving ECT
2021 · External reference
Electroconvulsive therapy improves functional connectivity of the frontoparietal network and language network in patients with treatment-resistant depression
10.1016/j.ajp.2025.104756 · 2025 · External reference
Electroconvulsive therapy changes temporal dynamics of intrinsic brain activity in depressed patients
10.1016/j.psychres.2022.114732 · 2022 · External reference
Electroconvulsive therapy regulates brain connectome dynamics in patients with major depressive disorder
10.1016/j.biopsych.2024.03.012 · 2024 · External reference
Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients
10.1016/j.brs.2021.12.008 · 2022 · External reference
Whole-brain functional connectivity dynamics associated with electroconvulsive therapy treatment response
2022 · External reference
Behavioural relevance of spontaneous, transient brain network interactions in fMRI
10.1016/j.neuroimage.2020.117713 · 2021 · External reference
Discovery of key whole-brain transitions and dynamics during human wakefulness and non-REM sleep
10.1038/s41467-019-08934-3 · 2019 · External reference
Brain network dynamics in schizophrenia: reduced dynamism of the default mode network
10.1002/hbm.24519 · 2019 · External reference
Reconfiguration of brain network dynamics in bipolar disorder: a hidden markov model approach
10.1038/s41398-024-03212-3 · 2024 · External reference
Altered brain dynamic in major depressive disorder: state and trait features
10.1038/s41398-023-02540-0 · 2023 · External reference
ECT in treatment-resistant depression
10.1176/appi.ajp.2012.12050648 · 2012 · External reference
Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients
10.1016/s0925-4927(03)00003-9 · 2003 · External reference
JuSpace: a tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps
10.1002/hbm.25244 · 2021 · External reference
Dose equivalents of antidepressants: evidence-Based recommendations from randomized controlled trials
10.1016/j.jad.2015.03.021 · 2015 · External reference
Hypnotic discontinuation in chronic insomnia
10.1016/j.jsmc.2022.06.014 · 2022 · External reference
RESTplus: an improved toolkit for resting-state functional magnetic resonance imaging data processing
10.1016/j.scib.2019.05.008 · 2019 · External reference
Brain network dynamics are hierarchically organized in time
10.1073/pnas.1705120114 · 2017 · External reference
Dynamic functional connectivity of the default mode network tracks daydreaming
10.1016/j.neuroimage.2014.06.044 · 2014 · External reference
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
10.1038/s41593-022-01186-3 · 2022 · External reference
Transition and dynamic reconfiguration of whole-brain network in major depressive disorder
10.1007/s12035-020-01995-2 · 2020 · External reference
Control of goal-directed and stimulus-driven attention in the brain
10.1038/nrn755 · 2002 · External reference
Dorsal and ventral attention systems: distinct neural circuits but collaborative roles
10.1177/1073858413494269 · 2014 · External reference
Dynamic neural network modulation associated with rumination in major depressive disorder: a prospective observational comparative analysis of cognitive behavioral therapy and pharmacotherapy
10.1038/s41398-025-03489-y · 2025 · External reference
Disrupted intrinsic functional brain topology in patients with major depressive disorder
10.1038/s41380-021-01247-2 · 2021 · External reference
Decreased dorsal attention network homogeneity as a potential neuroimaging biomarker for major depressive disorder
10.1016/j.jad.2023.03.080 · 2023 · External reference
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA major depressive disorder working group
10.1038/mp.2015.69 · 2016 · External reference
The impact of cortical and subcortical volumes on major depression risk: a genetic study
10.1016/j.jad.2025.01.069 · 2025 · External reference
Social support mediates the influence of cerebellum functional connectivity strength on postpartum depression and postpartum depression with anxiety
10.1038/s41398-022-01781-9 · 2022 · External reference
Group-guided individual functional parcellation of the hippocampus and application to normal aging
10.1002/hbm.25662 · 2021 · External reference
Semi-metric topology of the human connectome: sensitivity and specificity to autism and major depressive disorder
10.1371/journal.pone.0136388 · 2015 · External reference
Mapping intrinsic functional network topological architecture in major depression disorder after electroconvulsive therapy
10.1016/j.jad.2022.05.067 · 2022 · External reference
Structural plasticity of the hippocampus and amygdala induced by electroconvulsive therapy in major depression
10.1016/j.biopsych.2015.02.029 · 2016 · External reference
The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse
10.1038/s41598-020-79170-9 · 2020 · External reference
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
10.1073/pnas.0504136102 · 2005 · External reference
The default mode network in cognition: a topographical perspective
10.1038/s41583-021-00474-4 · 2021 · External reference
All roads lead to the default-mode network-global source of DMN abnormalities in major depressive disorder
10.1038/s41386-020-0785-x · 2020 · External reference
Rumination and the default mode network: meta-Analysis of brain imaging studies and implications for depression
10.1016/j.neuroimage.2019.116287 · 2020 · External reference
Movement, mood and cognition: preliminary insights into the therapeutic effects of electroconvulsive therapy for depression through a resting-state connectivity analysis
10.1016/j.jad.2021.04.069 · 2021 · External reference
Disrupted intrinsic functional connectivity of the cognitive control network underlies disease severity and executive dysfunction in first-episode, treatment-naive adolescent depression
10.1016/j.jad.2019.11.076 · 2020 · External reference
A comprehensive overview of the role of visual cortex malfunction in depressive disorders: opportunities and challenges
10.1007/s12264-023-01052-7 · 2023 · External reference
More optimal but less regulated dorsal and ventral visual networks in patients with major depressive disorder
10.1016/j.jpsychires.2019.01.005 · 2019 · External reference
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
10.1038/nm.4050 · 2016 · External reference
Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder
10.1016/j.biopsych.2008.10.025 · 2009 · External reference
Increased cortical GABA concentrations in depressed patients receiving ECT
10.1176/appi.ajp.160.3.577 · 2003 · External reference
Increased 5-HT(2A) receptor binding in euthymic, medication-free patients recovered from depression: a positron emission study with [(11)C]MDL 100,907
10.1176/ajp.2006.163.9.1580 · 2006 · External reference
Norepinephrine transporter in major depressive disorder: a PET study
10.1176/appi.ajp.2016.15101334 · 2017 · External reference
Neuromodulation by acetylcholine: examples from schizophrenia and depression
10.1016/j.conb.2014.06.004 · 2014 · External reference
The cholinergic system and hippocampal plasticity
10.1016/j.bbr.2010.11.037 · 2011 · External reference
Localized connectivity in depression: a meta-analysis of resting state functional imaging studies
10.1016/j.neubiorev.2015.01.006 · 2015 · External reference
Motor circuits and beyond: functional connectivity related to psychomotor syndromes in depression
10.1017/s0033291725101852 · 2025 · External reference
Test-retest reliabilities of resting-state FMRI measurements in human brain functional connectomics: a systems neuroscience perspective
10.1016/j.neubiorev.2014.05.009 · 2014 · External reference
Dynamic functional connectivity: promise, issues, and interpretations
10.1016/j.neuroimage.2013.05.079 · 2013 · External reference
Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?
10.1016/j.neuroimage.2015.11.055 · 2016 · External reference