References

Promises and challenges of a decentralized CAR T-cell manufacturing model

10.3389/frtra.2023.1238535 · 2023 · External reference

Should we adopt an automated de-centralized model of chimeric antigen receptor- T cells manufacturing for low-and middle-income countries? A real world perspective

10.3389/fonc.2022.1062296 · 2022 · External reference

Cryopreservation: An Overview of Principles and Cell-Specific Considerations

10.1177/0963689721999617 · 2021 · External reference

Dimethyl Sulfoxide (DMSO) Decreases Cell Proliferation and TNF-α, IFN-γ, and IL-2 Cytokines Production in Cultures of Peripheral Blood Lymphocytes

10.3390/molecules22111789 · 2017 · External reference

Thawing and infusion of CAR-T cell products

10.46765/2675-374x.2022v3n1p165 · 2022 · External reference

Clinical manufacturing of CAR T cells: foundation of a promising therapy

10.1038/mto.2016.15 · 2016 · External reference

CAR-T cell manufacturing: Major process parameters and next-generation strategies

10.1084/jem.20230903 · 2024 · External reference

Metabolism in T cell activation and differentiation

10.1016/j.coi.2010.01.018 · 2010 · External reference

Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

10.3389/fimmu.2015.00001 · 2015 · External reference

Metabolism and epigenetics at the heart of T cell function

10.1016/j.it.2023.01.002 · 2023 · External reference

Prolonged Cryopreservation Negatively Affects Embryo Transfer Outcomes Following the Elective Freeze-All Strategy: A Multicenter Retrospective Study

2021 · External reference

A quantitative analysis of the impact of cryopreservation on the implantation potential of human early cleavage stage embryos

10.1093/humrep/15.1.175 · 2000 · External reference

Mitochondrial Dysfunction and Oxidative Stress Caused by Cryopreservation in Reproductive Cells

10.3390/antiox10030337 · 2021 · External reference

Effects of Cryopreservation on Cell Metabolic Activity and Function of Biofabricated Structures Laden with Osteoblasts

10.3390/ma13081966 · 2020 · External reference

Investigation of Functional and Morphological Integrity of Freshly Isolated and Cryopreserved Human Hepatocytes

10.1023/a:1010175906791 · 2000 · External reference

Cryopreservation of isolated human hepatocytes for transplantation: State of the art

10.1016/j.cryobiol.2006.05.004 · 2006 · External reference

Human islet mass, morphology, and survival after cryopreservation using the Edmonton protocol

10.4161/isl.26304 · 2013 · External reference

Review of vitreous islet cryopreservation: Some practical issues and their resolution

10.4161/org.5.3.9812 · 2009 · External reference

Impact of Cryopreservation and Freeze-Thawing on Therapeutic Properties of Mesenchymal Stromal/Stem Cells and Other Common Cellular Therapeutics

10.1007/s40778-022-00212-1 · 2022 · External reference

Optical imaging using endogenous contrast to assess metabolic state

10.1146/annurev-bioeng-071811-150108 · 2012 · External reference

In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

10.1073/pnas.0708425104 · 2007 · External reference

Metabolically Linked Changes in Fluorescence Emission Spectra of Cortex of Rat Brain, Kidney and Adrenal Gland

10.1038/1951073a0 · 1962 · External reference

Molecular mechanism of metabolic NAD(P)H-dependent electron-transfer systems: The role of redox cofactors

10.1016/j.bbabio.2018.11.014 · 2019 · External reference

Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells

10.1364/boe.401935 · 2020 · External reference

Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling

10.1117/1.jbo.30.s2.s23901 · 2025 · External reference

Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD

10.1089/ars.2017.7451 · 2019 · External reference

Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on squamous cell carcinoma cultures

10.1117/1.jbo.26.10.106501 · 2021 · External reference

Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon

10.1038/s41598-018-23691-x · 2018 · External reference

Multiphoton fluorescence lifetime imaging microscopy reveals free-to-bound NADH ratio changes associated with metabolic inhibition

10.1117/1.jbo.19.8.086016 · 2014 · External reference

Classification of T-cell activation via autofluorescence lifetime imaging

10.1038/s41551-020-0592-z · 2021 · External reference

Time-domain single photon-excited autofluorescence lifetime for label-free detection of T cell activation

10.1364/ol.422445 · 2021 · External reference

Bax and Bak regulate T cell proliferation through control of ER Ca2+ homeostasis

10.1016/j.immuni.2007.05.023 · 2007 · External reference

Natural NADH and FAD Autofluorescence as Label-Free Biomarkers for Discriminating Subtypes and Functional States of Immune Cells

10.3390/ijms23042338 · 2022 · External reference

Bispecific anti-CD20, anti-CD19 CAR T cells for relapsed B cell malignancies: a phase 1 dose escalation and expansion trial

10.1038/s41591-020-1081-3 · 2020 · External reference

Immunophenotype of CAR T cells and apheresis products predicts response in CD22 CAR T cell trial for B cell acute lymphoblastic leukemia

10.1016/j.ymthe.2025.03.019 · 2025 · External reference

Label-free metabolic imaging monitors the fitness of chimeric antigen receptor T cells

10.1038/s41551-025-01504-7 · 2025 · External reference

Cryopreserved anti-CD22 and bispecific anti-CD19/22 CAR T cells are as effective as freshly infused cells

10.1016/j.omtm.2022.12.004 · 2023 · External reference

Concerns arising from MSC retrieval from cryostorage and effect on immune suppressive function and pharmaceutical usage in clinical trials

10.1111/voxs.12022 · 2013 · External reference

The impact of cryopreservation on human peripheral blood leucocyte bioenergetics

10.1042/cs20140725 · 2015 · External reference

Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer cell (NK) activity in 51Cr-release and CD107a assays

10.1016/j.jim.2014.01.017 · 2014 · External reference

Hepatocellular Metabolic Profile: Understanding Post-Thawing Metabolic Shift in Primary Hepatocytes In Vitro

10.3390/cells14110803 · 2025 · External reference

Quantitative assessment of the impact of cryopreservation on human bone marrow-derived mesenchymal stem cells: up to 24 h post-thaw and beyond

10.1186/s13287-020-02054-2 · 2020 · External reference

Cryopreservation affected the levels of immune responses of PBMCs and antigen-presenting cells

10.1016/j.tiv.2020.104918 · 2020 · External reference

Post-Thaw Culture and Measurement of Total Cell Recovery Is Crucial in the Evaluation of New Macromolecular Cryoprotectants

10.1021/acs.biomac.0c00591 · 2020 · External reference

Assessment of the Impact of Post-Thaw Stress Pathway Modulation on Cell Recovery following Cryopreservation in a Hematopoietic Progenitor Cell Model

10.3390/cells11020278 · 2022 · External reference

Simultaneous NAD(P)H and FAD fluorescence lifetime microscopy of long UVA–induced metabolic stress in reconstructed human skin

10.1038/s41598-021-00126-8 · 2021 · External reference

Fluorescence lifetime imaging of NAD(P)H upon oxidative stress in Kluyveromyces marxianus

10.3389/fbioe.2022.998800 · 2022 · External reference

Unresolved reference

External reference

T Cell Fitness and Autologous CAR T Cell Therapy in Haematologic Malignancy

10.3389/fimmu.2021.780442 · 2021 · External reference

Cryopreservation and its clinical applications

10.1016/j.imr.2016.12.001 · 2017 · External reference

FLIM Playground: An interactive, end-to-end graphical user interface for analyzing single-cell fluorescence lifetime data

2025 · External reference