Research graph
References from VIDA: A programmable gasdermin-mediated strategy to broaden mRNA therapeutics. Local targets link to admitted publications; unresolved targets remain external evidence.
Mechanistic insights into gasdermin-mediated pyroptosis
10.1038/s41580-025-00837-0 · 2025 · External reference
Channelling inflammation: gasdermins in physiology and disease
10.1038/s41573-021-00154-z · 2021 · External reference
Lipid nanoparticle-encapsulated mRNA antibody provides long-term protection against SARS-CoV-2 in mice and hamsters
10.1038/s41422-022-00630-0 · 2022 · External reference
Efficacy and safety of an mRNA encoding neutralizing antibody against SARS-CoV-2 in non-human primates
10.1016/j.scib.2025.03.055 · 2025 · External reference
Pan-membrane pyroptosis of liver induced by gasdermin-encoding mRNAs
10.1093/nsr/nwaf452 · 2026 · External reference
mRNA lipid nanoparticle-mediated pyroptosis sensitizes immunologically cold tumors to checkpoint immunotherapy
10.1038/s41467-023-39938-9 · 2023 · External reference
Viral protease-initiated lytic cell death as a universal antiviral mRNA therapy
10.1016/j.cell.2026.06.031 · 2026 · External reference
A Thermostable mRNA Vaccine against COVID-19
10.1016/j.cell.2020.07.024 · 2020 · External reference
Efficacy, immunogenicity, and safety of a monovalent mRNA vaccine, ABO1020, in adults: A randomized, double-blind, placebo-controlled, phase 3 trial
10.1016/j.medj.2024.06.013 · 2024 · External reference
Cell death in cancer
10.1016/j.cell.2026.03.024 · 2026 · External reference