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References from Targeting the tumor, harboring the host: IL-7 receptor-targeted CARs to treat T-ALL. Local targets link to admitted publications; unresolved targets remain external evidence.
An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies
10.1038/s41375-018-0065-5 · 2018 · External reference
IL7-receptor-targeted CAR T-cell therapy for T-cell acute lymphoblastic leukemia
10.1038/s41467-026-75675-5 · 2026 · External reference
Overexpression of wild-type IL-7Ralpha promotes T-cell acute lymphoblastic leukemia/lymphoma
10.1182/blood.2019000553 · 2021 · External reference
IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition
2023 · External reference
Tumor antigen escape from CAR T-cell therapy
10.1158/2159-8290.cd-18-0442 · 2018 · External reference
T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape
10.1038/s41392-022-00898-z · 2022 · External reference
Differential regulation of human IL-7 receptor alpha expression by IL-7 and TCR signaling
10.4049/jimmunol.180.8.5201 · 2008 · External reference
Affinity-tuned ErbB2 or EGFR chimeric antigen receptor T cells exhibit an increased therapeutic index against tumors in mice
10.1158/0008-5472.can-15-0159 · 2015 · External reference
CAR T cells targeting CD99 as an approach to eradicate T-cell acute lymphoblastic leukemia without normal blood cells toxicity
10.1186/s13045-021-01178-z · 2021 · External reference
Universal base-edited CAR7 T cells for T-cell acute lymphoblastic leukemia
10.1056/nejmoa2505478 · 2026 · External reference
