Research graph
References from FOXM1 drives cisplatin resistance in ovarian cancer through STIM1-mediated SOCE and STAT1 activation. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2025
2025 · External reference
Ovarian cancer statistics, 2018
2018 · External reference
Epidemiology of ovarian cancer: a review
10.20892/j.issn.2095-3941.2016.0084 · 2017 · External reference
Treatment of epithelial ovarian cancer
2020 · External reference
Drug resistance in ovarian cancer: from mechanism to clinical trial
10.1186/s12943-024-01967-3 · 2024 · External reference
FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance
10.1016/j.bbagrm.2014.09.016 · 2014 · External reference
The emerging roles of forkhead box (Fox) proteins in cancer
10.1038/nrc2223 · 2007 · External reference
FOXM1-induced PRX3 regulates stemness and survival of colon cancer cells via maintenance of mitochondrial function
10.1053/j.gastro.2015.06.007 · 2015 · External reference
FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation
10.1091/mbc.e19-07-0413 · 2020 · External reference
FOXM1 in cancer: Interactions and vulnerabilities
10.1158/0008-5472.can-16-3566 · 2017 · External reference
FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients
10.1186/s13046-017-0536-y · 2017 · External reference
FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells
10.18632/oncotarget.2957 · 2015 · External reference
FOXM1 induces therapy resistance and inhibits apoptosis in a variety of human cancers
10.1038/s41419-025-08321-5 · 2026 · External reference
Calcium signaling and cell cycle: Progression or death
10.1016/j.ceca.2017.07.006 · 2018 · External reference
The calcium-cancer signalling nexus
10.1038/nrc.2017.18 · 2017 · External reference
Remodeling of calcium signaling in tumor progression
10.1186/1423-0127-20-23 · 2013 · External reference
Calcium signals and potential therapy targets in ovarian cancer (Review)
10.3892/ijo.2023.5573 · 2023 · External reference
Activation and regulation of store-operated calcium entry
10.1111/j.1582-4934.2010.01168.x · 2010 · External reference
Store-operated Ca2+ entry in tumor progression: From molecular mechanisms to clinical implications
10.3390/cancers11070899 · 2019 · External reference
Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca2+ entry-mediated turnover of focal adhesions
10.1186/s12929-020-00630-5 · 2020 · External reference
Depletion of intracellular Ca2+ induces FOXM1 SUMOylation and accumulation on the inner nuclear membrane and accelerates G2/M cell cycle transition
10.1016/j.ejcb.2023.151332 · 2023 · External reference
STIM1-mediated calcium signalling in cancer: Its relation to tumour aggressiveness and therapeutic horizons
10.1016/j.bbcan.2025.189420 · 2025 · External reference
Construction of store-operated calcium entry-related gene signature for predicting prognosis and indicates immune microenvironment infiltration in stomach adenocarcinomas
10.1038/s41598-024-73324-9 · 2024 · External reference
GEPIA3: Enhanced drug sensitivity and interaction network analysis for cancer research
10.1093/nar/gkaf423 · 2025 · External reference
The transcription factor FOXM1 is a cellular target of the natural product thiostrepton
10.1038/nchem.1114 · 2011 · External reference
The eukaryotic promoter database in its 30th year: focus on non-vertebrate organisms
10.1093/nar/gkw1069 · 2017 · External reference
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
10.1093/nar/gkad1059 · 2024 · External reference
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
10.1038/s41467-019-09234-6 · 2019 · External reference
The Reactome Pathway Knowledgebase 2024
10.1093/nar/gkad1025 · 2024 · External reference
Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth
10.1158/1078-0432.ccr-11-3225 · 2012 · External reference
Inhibition of the JAK/STAT pathway with ruxolitinib overcomes cisplatin resistance in non-small-cell lung cancer NSCLC
10.1007/s10495-014-1030-z · 2014 · External reference
ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair
10.18632/oncotarget.22488 · 2017 · External reference
The diverse repertoire of ISG15: more intricate than initially thought
10.1038/s12276-022-00872-3 · 2022 · External reference
ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap
10.1093/nar/gkv468 · 2015 · External reference
Glucotropaeolin promotes apoptosis by calcium dysregulation and attenuates cell migration with FOXM1 suppression in pancreatic cancer cells
10.3390/antiox12020257 · 2023 · External reference
Gene expression regulation by Ca2+ signaling: an updated systematic review
10.1186/s11658-026-00872-5 · 2026 · External reference
Harmonizome 3.0: integrated knowledge about genes and proteins from diverse multi-omics resources
10.1093/nar/gkae1080 · 2025 · External reference
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
10.1093/database/baw100 · 2016 · External reference
STIM1 mediates calcium-dependent epigenetic reprogramming in pancreatic cancer
10.1158/0008-5472.can-20-2874 · 2021 · External reference
Orai1 and STIM1 mediate SOCE and contribute to apoptotic resistance of pancreatic adenocarcinoma
10.1016/j.bbamcr.2014.02.012 · 2014 · External reference
Store operated calcium entry is altered by the inhibition of receptors tyrosine kinase
10.18632/oncotarget.24685 · 2018 · External reference
The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum
10.1038/s41590-018-0287-8 · 2019 · External reference
cGAS-STING pathway in cancer biotherapy
10.1186/s12943-020-01247-w · 2020 · External reference
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
10.1016/j.ccr.2011.08.016 · 2011 · External reference
Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation
10.1074/jbc.m703573200 · 2007 · External reference
