Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Process intensification of lipid nanoparticle manufacturing via vortex-enhanced flow synthesis: from design to functional mRNA delivery. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1201/9781003508601-8
10.1201/9781003508601-8 · External reference
Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment
10.1016/s0140-6736(21)00306-8 · 2021 · External reference
Cellular uptake of nanoparticles: journey inside the cell
10.1039/c6cs00636a · 2017 · External reference
Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs
10.1016/j.dmpk.2021.100424 · 2021 · External reference
Economic analysis of integrated continuous and batch pharmaceutical manufacturing: a case study
10.1021/ie2006752 · 2011 · External reference
The hitchhiker’s guide to flow chemistry∥
10.1021/acs.chemrev.7b00183 · 2017 · External reference
Continuous flow synthesis: a promising platform for the future of nanoparticle-based drug delivery
2024 · External reference
Scalable mRNA and siRNA lipid nanoparticle production using a parallelized microfluidic device
10.1021/acs.nanolett.1c01353 · 2021 · External reference
Flow chemistry: recent developments in the synthesis of pharmaceutical products
10.1021/acs.oprd.5b00325 · 2016 · External reference
How to approach flow chemistry
10.1039/c9cs00832b · 2020 · External reference
Microfluidic vortex focusing for high throughput synthesis of size-tunable liposomes
10.1038/s41467-022-34750-3 · 2022 · External reference
Synthesizing lipid nanoparticles by turbulent flow in confined impinging jet mixers
2024 · External reference
Three-dimensional-printed vortex tube reactor for continuous flow synthesis of polyglycolic acid nanoparticles with high productivity
10.3390/nano13192679 · 2023 · External reference
Key fabrications of chitosan nanoparticles for effective drug delivery using flow chemistry reactors
10.2147/ijn.s433756 · 2023 · External reference
Optimization of lipid-based nanoparticles formulation loaded with biological product using a novel design vortex tube reactor via flow chemistry
10.2147/ijn.s474775 · 2024 · External reference
Development and evaluation of drug-loaded niosomes fabricated by flow chemistry: a novel vortex tube reactor approach
10.1016/j.onano.2025.100243 · 2025 · External reference
A careful look at lipid nanoparticle characterization: analysis of benchmark formulations for encapsulation of RNA cargo size gradient
10.1038/s41598-024-52685-1 · 2024 · External reference
mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability
10.1016/j.ijpharm.2021.120586 · 2021 · External reference
Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization
2017 · External reference
Quantification of objective concentrations of DNA impurities in mRNA vaccines
10.1016/j.vaccine.2025.127022 · 2025 · External reference
Conjugation of mannans to enhance the potency of liposome nanoparticles for the delivery of RNA vaccines
10.3390/pharmaceutics13020240 · 2021 · External reference
Continuous-flow production of liposomes with a millireactor under varying fluidic conditions
10.3390/pharmaceutics12111001 · 2020 · External reference
Microfluidic fabrication of monodispersed pharmaceutical colloidal spheres of atorvastatin calcium with tunable sizes
10.1021/ie901365w · 2010 · External reference
Precise control of liposome size using characteristic time depends on solvent type and membrane properties
10.1038/s41598-023-31895-z · 2023 · External reference
Manufacturing considerations for the development of lipid nanoparticles using microfluidics
10.3390/pharmaceutics12111095 · 2020 · External reference
Naturally derived membrane lipids impact nanoparticle-based messenger RNA delivery
10.1007/s12195-020-00619-y · 2020 · External reference
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
10.1021/ja301621z · 2012 · External reference
Simulating copolymeric nanoparticle assembly in the co-solvent method: how mixing rates control final particle sizes and morphologies
10.1016/j.polymer.2017.07.057 · 2017 · External reference
On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
10.1021/acsnano.8b01516 · 2018 · External reference
Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA
10.1038/mtna.2012.28 · 2012 · External reference
Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines
10.1016/j.omtn.2019.01.013 · 2019 · External reference
Retention characteristics of sterile filters–effect of pore size and structure
10.1016/j.memsci.2021.119436 · 2021 · External reference
Process development of tangential flow filtration and sterile filtration for manufacturing of mRNA-lipid nanoparticles: a study on membrane performance and filtration modeling
10.1016/j.ijpharm.2025.125520 · 2025 · External reference
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
10.1016/j.jconrel.2016.05.059 · 2016 · External reference
The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer
10.1038/gt.2008.60 · 2008 · External reference
Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
10.1042/bj20031253 · 2004 · External reference
Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis
10.1038/mt.2013.54 · 2013 · External reference
Comparative analysis of lipid Nanoparticle-Mediated delivery of CRISPR-Cas9 RNP versus mRNA/sgRNA for gene editing in vitro and in vivo
10.1016/j.ejpb.2024.114207 · 2024 · External reference
Lab-scale siRNA and mRNA LNP manufacturing by various microfluidic mixing techniques–an evaluation of particle properties and efficiency
10.1016/j.onano.2023.100161 · 2023 · External reference