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References from Caracterización microbiológica de las exacerbaciones en el asma grave y su impacto en la toma de decisiones terapéuticas. Local targets link to admitted publications; unresolved targets remain external evidence.
M. Global, regional, national burden of asthma from 1990 to 2021, with projections of incidence to 2050: A systematic analysis of the global burden of disease study 2021
2025 · External reference
Characterization of severe asthma worldwide: Data from the International Severe Asthma Registry
10.1016/j.chest.2019.10.053 · 2020 · External reference
Global burden of chronic respiratory diseases and risk factors, 1990-2019: An update from the Global Burden of Disease Study 2019
2023 · External reference
Prevalence T2 biomarkers, and cost of severe asthma in the era of biologics: The BRAVO-1 Study
10.18176/jiaci.0871 · 2024 · External reference
Economic impact of severe asthma in Spain: Multicentre observational longitudinal study
10.1080/02770903.2018.1499035 · 2019 · External reference
Economic impact of severe asthma exacerbations in Spain: multicentre observational study
10.1080/02770903.2019.1674330 · 2021 · External reference
Severe asthma units in Spain: Enhancing patient care and research in severe asthma
10.1016/j.opresp.2025.100474 · 2025 · External reference
Cost effectiveness of outpatient asthma clinics
10.1016/j.arbres.2015.09.009 · 2016 · External reference
Interrupting the conversation: Implications for crosstalk between viral and bacterial infections in the asthmatic airway
10.3389/falgy.2021.738987 · 2021 · External reference
J. Asthma Inception: Epidemiologic risk factors and natural history across the life course
10.1164/rccm.202312-2249so · 2024 · External reference
Epidemiology of asthma across the ages
10.1016/j.anai.2024.12.004 · 2025 · External reference
Infección y asma [Infection and asthma]
2025 · External reference
The role of viruses in acute exacerbations of asthma
10.1016/j.jaci.2010.04.021 · 2010 · External reference
Viruses and bacteria in acute asthma exacerbations--a GA2 LEN-DARE systematic review
10.1111/j.1398-9995.2010.02505.x · 2011 · External reference
Prevalence of viral respiratory infections amongst asthmatics: Results of a meta-regression analysis
10.1016/j.rmed.2020.106020 · 2020 · External reference
The importance of bacterial and viral infections associated with adult asthma exacerbations in clinical practice
10.1371/journal.pone.0123584 · 2015 · External reference
Unresolved reference
2025 · External reference
Antibiotics for exacerbations of asthma
2018 · External reference
A real-life comparative effectiveness study into the addition of antibiotics to the management of asthma exacerbations in primary care
10.1183/13993003.03599-2020 · 2021 · External reference
EAACI Task Force on Conscious and Rational use of Antibiotics in Allergic Diseases. A survey study on antibiotic prescription practices for acute asthma exacerbations: An European academy of allergy and clinical immunology task force report
10.1002/clt2.12345 · 2024 · External reference
Real-world effectiveness of antibiotics in addition to oral corticosteroids for managing asthma exacerbations in adults
2025 · External reference
Medical algorithms: Approach to adult asthma exacerbations
10.1111/all.14976 · 2021 · External reference
Antibiotics for asthma attacks: Masking uncertainty
10.1183/13993003.00183-2021 · 2021 · External reference
Antibiotics for acute wheezing and asthma exacerbations: An EAACI position paper and systematic review
10.1111/all.70091 · 2025 · External reference
Applying precision medicine to the heterogeneity of asthma attacks
10.1016/j.chest.2025.11.013 · 2026 · External reference
Versión 5.5
2025 · External reference
Performance of the BIOFIRE® Filmarray Pneumonia Plus Panel for quantifiable bacterial targets compared to semiquantitative culture methods: A systematic review and meta-analysis
10.1016/j.jinf.2026.106683 · 2026 · External reference
Semi-quantitative detection of respiratory pathogens: A systematic review and meta-analysis of results from the BIOFIRE FILMARRAY pneumonia panel and culture
10.1002/mbo3.70086 · 2026 · External reference
Asthma exacerbations: Origin, effect, and prevention
10.1016/j.jaci.2011.10.024 · 2011 · External reference
Asthma Exacerbations in a Tertiary Hospital: Clinical Features Triggers, and Risk Factors for Hospitalization
10.18176/jiaci.0128 · 2024 · External reference
Evaluation of the BioFire® FilmArray® Pneumonia Panel with Conventional Bacterial Culture in Conjunction with Leukocyte Esterase Test
10.3390/diagnostics13111847 · 2023 · External reference
Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections
10.1128/jcm.00135-20 · 2020 · External reference
Real-life Assessment of BioFire FilmArray Pneumonia Panel in Adults Hospitalized With Respiratory Illness
10.1093/infdis/jiad221 · 2024 · External reference
Implementation of Point-of-Care PCR-testing for the diagnosis of respiratory infections in vulnerable patient populations
10.1371/journal.pone.0307621 · 2025 · External reference
How does comorbid bronchiectasis affect asthmatic patients? A meta-analysis
10.1080/02770903.2020.1784194 · 2021 · External reference
Impact of asthma on bronchiectasis severity and risk of exacerbations
10.1080/02770903.2020.1857395 · 2022 · External reference
Does asthma-bronchiectasis overlap syndrome (ABOS) really exist?
10.1080/02770903.2023.2203743 · 2023 · External reference
EMBARC registry investigators. Bronchiectasis and asthma: Data from the European Bronchiectasis Registry (EMBARC)
10.1016/j.jaci.2024.01.027 · 2024 · External reference
Bacteria and viruses and clinical outcomes of asthma-bronchiectasis overlap syndrome: A cohort study
10.1002/clt2.12331 · 2024 · External reference
Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma
10.1371/journal.pone.0100645 · 2014 · External reference
Refractory asthma: importance of bronchoscopy to identify phenotypes and direct therapy
10.1378/chest.11-0741 · 2012 · External reference
Redefining the Role of Bronchoscopy in the Workup of Severe Uncontrolled Asthma in the Era of Biologics: A Prospective Study
10.1016/j.chest.2023.03.012 · 2023 · External reference
Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology
10.1016/j.jaci.2017.03.044 · 2018 · External reference
Asthma is associated with increased Streptococcus pneumoniae carriage in the upper airway: A systematic review and meta-analysis
10.1080/20018525.2025.2569129 · 2025 · External reference
Enhanced detection of respiratory pathogens using PCR in COPD and asthma exacerbations
2025 · External reference
U-BIOPRED consortium Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation
10.1111/all.15776 · 2023 · External reference
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia
10.1002/ctm2.70007 · 2024 · External reference
Association of antibiotic treatment with outcomes in patients hospitalized for an asthma exacerbation treated with systemic corticosteroids
10.1001/jamainternmed.2018.5394 · 2019 · External reference
Inappropriate use of antibiotics for acute asthma in United States emergency departments
10.1111/j.1553-2712.2008.00167.x · 2008 · External reference
Uncertainty as a critical determinant of antibiotic prescribing in patients with an asthma exacerbation: A qualitative study
10.1080/02770903.2020.1847929 · 2022 · External reference
Phenotyping asthma exacerbations: One step further in the management of severe asthma
10.18176/jiaci.1043 · 2025 · External reference