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References from Hemoporfin research progress – Part II: Clinical applications of Hemoporfin PDT for the treatment of port-wine stain (PWS) birthmarks. Local targets link to admitted publications; unresolved targets remain external evidence.
Port-wine stains: a focused review on their management
2017 · External reference
Quality of life in adults with facial port-wine stains
10.1016/j.jaad.2016.10.039 · 2017 · External reference
Influence of port-wine stains on quality of life of children and their parents
10.2340/00015555-3883 · 2021 · External reference
An overview of clinical and experimental treatment modalities for port wine stains
10.1016/j.jaad.2011.11.938 · 2012 · External reference
Pulsed dye laser-resistant port-wine stains: mechanisms of resistance and implications for treatment
10.1111/bjd.12204 · 2013 · External reference
Early history of clinical application of photosensitizing drugs in photodynamic therapy (PDT) of portwine stain (PWS) birthmarks
10.1016/j.pdpdt.2024.104383 · 2024 · External reference
Research progress of Hemoporfin - part one: preclinical study
10.1016/j.pdpdt.2011.09.004 · 2012 · External reference
Absorptive characteristics of HMME and HpD in chicken comb skin and vascular endothelial cells
2001 · External reference
Single oxygen quantum yields of porphyrin-based photosensitizers for photodynamic therapy
10.1142/s1793545808000169 · 2008 · External reference
Tolerance and pharmacokinetics of single-dose intravenous Hemoporfin in healthy volunteers
10.1038/aps.2011.132 · 2011 · External reference
Study of pharmacokinetics and cutaneous photosensitization of Hemoporfin in healthy volunteers
2019 · External reference
Efficacy and safety of hemoporfin in photodynamic therapy for port-wine stain: a multicenter and open-labeled phase ⅱa study
10.1111/j.1600-0781.2010.00555.x · 2011 · External reference
A dose-finding study for hemoporfin in photodynamic therapy for port-wine stain: a multicenter randomized double-blind phase ⅱb trial
10.1111/phpp.12384 · 2018 · External reference
Hemoporfin photodynamic therapy for port-wine stain: a randomized controlled trial
10.1371/journal.pone.0156219 · 2016 · External reference
Efficacy and safety of hemoporfin photodynamic therapy in treating port-wine stains in Chinese children: a systematic review and meta-analysis
10.3389/fped.2024.1501401 · 2025 · External reference
Population pharmacokinetics and exposure-response relationship of hemoporfin in pediatric patients with port-wine stain
10.1002/psp4.70050 · 2025 · External reference
Clinical efficacy and safety of two different hematoporphyrin monomethyl ether-mediated photodynamic therapy regimen in Chinese children with port-wine stain
10.1111/exd.14834 · 2023 · External reference
Clinical study on hematoporphyrin monomethyl ether in the treatment of children with port wine stain at different drug-light intervals based on non-invasive detection technology
2025 · External reference
A clinical study of HMME-PDT therapy in Chinese pediatric patients with port-wine stain
10.1016/j.pdpdt.2018.06.006 · 2018 · External reference
General anaesthesia for photodynamic therapy of port-wine stain in children: a retrospective study
10.1016/j.pdpdt.2023.103273 · 2023 · External reference
Efficacy and safety of hemoporfin photodynamic therapy for port-wine stains in paediatric patients: a retrospective study of 439 cases at a single centre
10.1016/j.pdpdt.2021.102568 · 2021 · External reference
Evaluation of efficacy of Hemoporfin PDT in the treatment of PWS birthmarks of young children previously received PDL treatment
2024 · External reference
Comparing the clinical efficacy of hemoporfin-mediated photodynamic therapy for port wine stains in children with prior pulsed dye laser treatment history
2025 · External reference
Correlation between dermoscopic vascular characteristics and efficacy of hematoporphyrin monomethyl ether-photodynamic therapy on port-wine stain in children
2025 · External reference
Clinical study on Hemoporfin PDT for infant facial port-wine stains
10.1016/j.pdpdt.2018.09.012 · 2019 · External reference
Retrospective analysis of the correlation between dermoscopic vascular features and the response to Hemoporfin-mediated photodynamic therapy in previously untreated children with port wine stains
10.1016/j.pdpdt.2025.104691 · 2025 · External reference
Clinical efficacy of Hemoporfin photodynamic therapy in treating 67 patients with port-wine stains
2023 · External reference
Clinical study on clinical operation and post-treatment reactions of HMME-PDT in treatment of PWS
10.1016/j.pdpdt.2017.09.013 · 2017 · External reference
Retrospective study of photodynamic therapy for pulsed dye laser-resistant port-wine stains
10.1111/1346-8138.15238 · 2020 · External reference
Hemoporfin-mediated photodynamic therapy for the treatment of port-wine stain: a multicenter, retrospective study
10.1016/j.pdpdt.2023.103545 · 2023 · External reference
Hemoporfin-mediated photodynamic therapy with general anesthesia showed superior efficacy in the treatment of port-wine stains: a retrospective evaluation
10.3389/fmed.2023.1170520 · 2023 · External reference
Efficacy of Hemoporfin PDT on port-wine stains: a retrospective analysis of 2952 cases
10.1016/j.pdpdt.2023.103837 · 2023 · External reference
Efficacy of photodynamic therapy of port-wine stains resistant to pulsed dye laser therapy
2022 · External reference
Is HMME-PDT the first choice of treatment for young children with port-wine stain birthmarks?
10.1002/lsm.23831 · 2024 · External reference
Hematoporphyrin monomethyl ether photodynamic therapy for the treatment of facial port-wine stains resistant to pulsed dye laser
10.1016/j.pdpdt.2020.101820 · 2020 · External reference
Unresolved reference
2024 · External reference
Effectiveness and safety of hematoporphyrin monomethyl ether mediated photodynamic therapy versus pulsed dye laser for port wine stain: a retrospective study
10.1016/j.jaad.2026.06.029 · 2026 · External reference
Retrospective analysis of Hemoporfin-mediated photodynamic therapy in the treatment of naive port-wine stains
10.1016/j.pdpdt.2022.103003 · 2022 · External reference
Efficacy and influential factors of hematoporphyrin monomethyl ether mediated photodynamic therapy in the treatment for port-wine stains
10.1016/j.pdpdt.2023.103933 · 2024 · External reference
Study of treatment and patient factors of hemoporfin-photodynamic therapy for port-wine stains
2024 · External reference
Efficacy of influential factors in hemoporfin-mediated photodynamic therapy for facial port-wine stains
10.1111/1346-8138.16094 · 2021 · External reference
Hemoporfin-mediated photodynamic therapy for port-wine stains: multivariate analysis of clinical efficacy and optical coherence tomography appearance
2022 · External reference
Influential factors in the efficacy and safety of hemoporfin-mediated photodynamic therapy for facial port-wine stains
10.1111/jocd.70153 · 2025 · External reference
Comparing HMME-PDT and Cynergy dual-wavelength laser in the treatment of facial PWS
10.1016/j.pdpdt.2021.102703 · 2022 · External reference
Ten-year long-term results following HMME-PDT therapy for port-wine stain
10.1002/tbio.202200004 · 2023 · External reference
Histological characteristics of port wine stains with complete regression after photodynamic therapy treatment: a 7 year follow up
2022 · External reference
18 years long term results of facial port wine stain (PWS) after photodynamic therapy (PDT) – a case report
10.1016/j.pdpdt.2014.09.004 · 2015 · External reference
Unresolved reference
2010 · External reference
Expert consensus on hematoporphyrin monomethyl ether-mediated photodynamic therapy for treating port-wine stains (2024)
2024 · External reference
Guideline for the diagnosis and treatment in laser and aesthetic medicine (2024)
2024 · External reference
Guideline of diagnosis and treatment of hemangioma and vascular malformation (2024)
2024 · External reference
Efficacy and related factors analysis in HMME-PDT in the treatment of port wine stains
10.1016/j.pdpdt.2020.101649 · 2020 · External reference
The association between treatment reactions and treatment efficiency of HMME-photodynamic therapy on port wine stains: a prospective double blind randomized controlled trial
10.1016/j.pdpdt.2017.02.005 · 2017 · External reference
Adverse effects associated with photodynamic therapy (PDT) of port-wine stain (PWS) birthmarks
10.1016/j.pdpdt.2012.03.007 · 2012 · External reference
Impact of general anesthesia on the photodynamic therapy of port wine stain: a retrospective study
2022 · External reference
Post treatment care in photodynamic therapy (PDT) of large facial port-wine stain (PWS) birthmarks
10.1016/j.pdpdt.2021.102604 · 2021 · External reference
Hematoporphyrin monomethyl ether photodynamic therapy for the treatment of Sturge-Weber syndrome and large segmental facial port-wine stain
10.1111/dth.15404 · 2022 · External reference
Sturge-Weber Syndrome with GNAQ mutation treated with hemoporfin photodynamic therapy: a case report
2024 · External reference
Retrospective study of photodynamic therapy for the GNA-Related Capillary malformation spectrum of pediatric patients
10.1016/j.pdpdt.2026.105448 · 2026 · External reference
Hemoporfin-mediated photodynamic therapy for angiokeratoma corporis diffusum: a case report
2024 · External reference
Simulating PDT of port-wine stains in the in vivo chicken wattle model using hemoporfin and radiation at 532 nm: comparison of a LED and a laser source
10.1016/j.pdpdt.2024.104068 · 2024 · External reference
Implementation and uniformity calibration of LED array for photodynamic therapy
10.1142/s1793545822400041 · 2022 · External reference
Three-dimensional image-guided topical photodynamic therapy system with light dosimetry dynamic planning and monitoring
10.1364/boe.481248 · 2023 · External reference
Research progress on lesion structure of port-wine stains and its optical imaging methods in vascular targeted photodynamic therapy
2022 · External reference
Application of different noninvasive diagnostic techniques used in HMME-PDT in the treatment of port wine stains
10.1016/j.pdpdt.2019.01.008 · 2019 · External reference
Efficacy of influential factors in hemoporfin-mediated photodynamic therapy for facial port-wine stains
10.1111/1346-8138.16094 · 2021 · External reference
Multimodal ultrasound manifestations of port-wine stains and their application in efficacy assessment of photodynamic therapy
2024 · External reference
Unresolved reference
External reference
Comparative study of laser doppler imaging and laser speckle imaging for non-destructive testing of port-wine stains
2014 · External reference
Fluorescence monitoring of a photosensitizer and prediction of the therapeutic effect of photodynamic therapy for port wine stains
10.1258/ebm.2009.009294 · 2010 · External reference
Lesion segmentation using 3D scan and deep learning for the evaluation of facial portwine stain birthmarks
10.1016/j.pdpdt.2024.104030 · 2024 · External reference
The effect of autophagy on hemoporfin-mediated photodynamic therapy in human umbilical vein endothelial cells
10.1016/j.pdpdt.2024.104196 · 2024 · External reference
Hemoporfin photodynamic therapy affects secretion, uptake, and function of human umbilical vein endothelial cell-derived exosomes via apoptosis and autophagy
10.1016/j.pdpdt.2026.105353 · 2026 · External reference
Expert consensus on diagnosis and treatment of port-wine stain in children (2025 edition)
2025 · External reference
Photodynamic therapy: clinical applications in dermatology
10.1016/j.jaad.2024.12.050 · 2026 · External reference
Laser and light based treatments for port wine birthmarks – a systematic review and network meta analysis
2025 · External reference
Side-by-side comparison of photodynamic therapy and pulsed dye laser for port-wine stains
10.1111/bjd.12130 · 2013 · External reference
Comparison of efficacy between hemoporfin photodynamic therapy and pulsed dye laser in the treatment of port-wine stains with different vascular patterns: a retrospective study
10.1111/phpp.70031 · 2025 · External reference
Comparison of the effects of hemoporfin-mediated photodynamic and vbeam pulsed dye laser in the treatment of port-wine stains: a retrospective analysis
10.1186/s40001-025-02820-z · 2025 · External reference
Efficacy and safety evaluation of 595 nm pulsed dye laser treatment in 120 cases of Asian infants with port wine stain
10.2147/ccid.s489305 · 2025 · External reference
The 595-nm wavelength pulsed dye laser for pediatric port-wine birthmarks and infantile hemangiomas: a systematic review
10.1002/lsm.23864 · 2025 · External reference
Weekly pulsed dye laser treatments for port-wine birthmarks in infants
10.1001/jamadermatol.2024.0293 · 2024 · External reference
Pulsed dye laser for port wine stains in 974 children: a 20-year study in China
10.2147/ccid.s487229 · 2024 · External reference
Photodynamic therapy in treatment of port wine stain birthmarks - recent progress
10.1016/j.pdpdt.2009.08.001 · 2009 · External reference
Combined benzoporphyrin derivative monoacid ring photodynamic therapy and pulsed dye laser for port wine stain birthmarks
10.1016/j.pdpdt.2009.10.002 · 2009 · External reference
Effect of skin color on optical properties and the implications for medical optical technologies: a review
10.1117/1.jbo.29.1.010901 · 2024 · External reference
Comparison of wavelength-dependent penetration depths of lasers in different types of skin in photodynamic therapy
10.1007/s12648-012-0213-0 · 2013 · External reference
Analysis of photon transport and detectability in skin tissue through Monte Carlo simulation of photosensitization-mediated fluorescence and singlet oxygen luminescence
10.1016/j.pdpdt.2026.105489 · 2026 · External reference
Port wine stain treatment outcomes have not improved over the past three decades
10.1111/jdv.15599 · 2019 · External reference