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References from Metabolic syndrome identifies a high-risk polypharmacy phenotype in older adults with syncope. Local targets link to admitted publications; unresolved targets remain external evidence.
2018 ESC Guidelines for the diagnosis and management of syncope
10.1093/eurheartj/ehy037 · 2018 · External reference
Vasovagal syncope: An overview of pathophysiological mechanisms
10.1016/j.ejim.2023.03.025 · 2023 · External reference
Epidemiology of Syncope/Collapse in Younger and Older Western Patient Populations
10.1016/j.pcad.2012.11.006 · 2013 · External reference
Evaluation of GFAP/UCH-L1 biomarkers for computed tomography exclusion in mild traumatic brain injury (mTBI)
10.1186/s12245-024-00708-z · 2024 · External reference
Diabetes influences cancer risk in patients with increased carotid atherosclerosis burden
10.1016/j.numecd.2019.11.016 · 2020 · External reference
Correction: Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis
10.1186/s12877-022-03388-7 · 2022 · External reference
Deprescribing in older adults with polypharmacy
10.1136/bmj-2023-074892 · 2024 · External reference
Medication Regimen Complexity and Number of Medications as Factors Associated With Unplanned Hospitalizations in Older People: A Population-based Cohort Study
10.1093/gerona/glv219 · 2016 · External reference
Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study
10.1186/s12877-023-04062-2 · 2023 · External reference
Frailty in elderly people
10.1016/s0140-6736(12)62167-9 · 2013 · External reference
Comparison of Incidence, Predictors, and the Impact of Co-Morbidity and Polypharmacy on the Risk of Recurrent Syncope in Patients <85 Versus ≥85 Years of Age
10.1016/j.amjcard.2013.07.041 · 2013 · External reference
Prevalence and impact of polypharmacy in older patients with type 2 diabetes
10.1007/s40520-022-02165-1 · 2022 · External reference
Risk of orthostatic hypotension associated with sodium-glucose cotransporter-2 inhibitor treatment: A meta-analysis of randomized controlled trials
10.1177/1479164120953625 · 2020 · External reference
Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis
10.1016/j.jash.2014.01.007 · 2014 · External reference
Efficacy, renal safety and tolerability of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in elderly patients with type 2 diabetes: A real-world experience
10.1016/j.pcd.2020.10.002 · 2021 · External reference
An Investigation of Metabolic Risk Factors and Gut Microbiota in Unexplained Syncope
10.3390/biomedicines12020264 · 2024 · External reference
A Metabolomic Approach to Unexplained Syncope
10.3390/biomedicines12112641 · 2024 · External reference
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
10.1016/0021-9681(87)90171-8 · 1987 · External reference
Metabolic syndrome—a new world-wide definition. A Consensus Statement from the International Diabetes Federation
10.1111/j.1464-5491.2006.01858.x · 2006 · External reference
Development and Validation of the Medication Regimen Complexity Index
10.1345/aph.1d479 · 2004 · External reference
Drug-Related Orthostatic Hypotension: Beyond Anti-Hypertensive Medications
10.1007/s40266-020-00796-5 · 2020 · External reference
Differences in youngest-old, middle-old, and oldest-old patients who visit the emergency department
10.15441/ceem.17.261 · 2018 · External reference
Effect of deprescribing in elderly patients with type 2 diabetes: iDegLira might improve quality of life
10.1016/j.biopha.2021.112341 · 2021 · External reference
Perspectives of Older Patients on the Complexity of Medication Use
10.1111/jgs.70311 · 2026 · External reference
The relation between age, sex, comorbidity, and pharmacotherapy and the risk of syncope: a Danish nationwide study
10.1093/europace/eus154 · 2012 · External reference
DARWIN-FUP network. Short-term effectiveness of dapagliflozin versus DPP-4 inhibitors in elderly patients with type 2 diabetes: a multicentre retrospective study
10.1007/s40618-022-02002-2 · 2023 · External reference
Blood pressure control in type 2 diabetes mellitus with arterial hypertension. The important ancillary role of SGLT2-inhibitors and GLP1-receptor agonists
10.1016/j.phrs.2020.105052 · 2020 · External reference
SGLT2-inhibitors are effective and safe in the elderly: The SOLD study
10.1016/j.phrs.2022.106396 · 2022 · External reference
Improved glycemic and weight control with Dulaglutide addition in SGLT2 inhibitor treated obese type 2 diabetic patients at high cardiovascular risk in a real-world setting. The AWARE-2 study
10.1016/j.phrs.2024.107517 · 2024 · External reference
Update on the Impact, Diagnosis and Management of Cardiovascular Autonomic Neuropathy in Diabetes: What Is Defined, What Is New, and What Is Unmet
10.4093/dmj.2018.0259 · 2019 · External reference
Unresolved reference
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Unresolved reference
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Stop vasodepressor drugs in reflex syncope: a randomised controlled trial
10.1136/heartjnl-2016-309865 · 2017 · External reference
Effect of discontinuation of antihypertensive medication on orthostatic hypotension in older persons with mild cognitive impairment: the DANTE Study Leiden
10.1093/ageing/afv199 · 2016 · External reference
The prevalence of polypharmacy in older Europeans: A multi-national database study of general practitioner prescribing
10.1111/bcp.16113 · 2024 · External reference
Dysregulation of the gut-adipose tissue-liver axis: a possible mechanism behind the relationship between metabolic dysfunction-associated steatotic liver disease and type 2 diabetes
10.1007/s11892-026-01623-8 · 2026 · External reference
Glycometabolic cardiac dysfunction in HFpEF: Lessons from multi-omics studies
10.1016/j.phrs.2025.108032 · 2025 · External reference