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References from Ophiopogonin D suppresses non-small cell lung cancer progression by targeting exosomal MALAT1 to enhance dendritic cell maturation. Local targets link to admitted publications; unresolved targets remain external evidence.
Clinical recommendations for perioperative immunotherapy-induced adverse events in patients with non-small cell lung cancer
10.1111/1759-7714.13942 · 2021 · External reference
Comprehensive insights and In silico analysis into the emerging role of LincRNAs in lung diseases pathogenesis; a step toward ncRNA precision
10.1007/s10142-025-01540-1 · 2025 · External reference
Treatment of non-small cell lung cancer using chem-bioinformatics-driven engineering of exosomal cargo-vehicle for telmisartan and pioglitazone targeted-delivery
10.1038/s41598-025-10416-0 · 2025 · External reference
The tumor immune microenvironment and T-cell-related immunotherapies in colorectal cancer
10.1007/s12672-024-01117-7 · 2024 · External reference
Collagen Type XI Inhibits Lung Cancer-Associated Fibroblast Functions and Restrains the Integrin Binding Site Availability on Collagen Type I Matrix
10.3390/ijms231911722 · 2022 · External reference
Cancer immunotherapies: advances and bottlenecks
10.3389/fimmu.2023.1212476 · 2023 · External reference
Distinctive CD8(+) T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells
10.1016/j.celrep.2025.115413 · 2025 · External reference
Targeting tumor-associated macrophages with mannosylated nanotherapeutics delivering TLR7/8 agonist enhances cancer immunotherapy
10.1016/j.jconrel.2024.06.062 · 2024 · External reference
Tumor microenvironment-related dendritic cell deficiency: a target to enhance tumor immunotherapy
10.1016/j.phrs.2020.104980 · 2020 · External reference
Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer
10.1016/bs.ircmb.2023.07.006 · 2024 · External reference
Non-small Cell Lung Cancer Cells Modulate the Development of Human CD1c(+) Conventional Dendritic Cell Subsets Mediated by CD103 and CD205
10.3389/fimmu.2019.02829 · 2019 · External reference
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
10.1016/j.ccell.2023.02.016 · 2023 · External reference
Microenvironment-driven metabolic adaptations guiding CD8(+) T cell anti-tumor immunity
10.1016/j.immuni.2022.12.008 · 2023 · External reference
Differential Signaling Pathways in Medulloblastoma: Nano-biomedicine Targeting Non-coding Epigenetics to Improve Current and Future Therapeutics
10.2174/0113816128277350231219062154 · 2024 · External reference
A Comprehensive Insight and In Silico Analysis of CircRNAs in Hepatocellular Carcinoma: A Step toward ncRNA-Based Precision Medicine
10.3390/cells13151245 · 2024 · External reference
Exosomal non-coding RNAs in glioma progression: insights into tumor microenvironment dynamics and therapeutic implications
10.3389/fcell.2023.1275755 · 2023 · External reference
Exosomes from 5-aminolevulinic acid photodynamic therapy-treated squamous carcinoma cells promote dendritic cell maturation
2020 · External reference
Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy
10.3389/fimmu.2020.00221 · 2020 · External reference
PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
10.1016/j.celrep.2020.108278 · 2020 · External reference
Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway
10.2147/ott.s256669 · 2020 · External reference
Ophiopogonin-D suppresses MDA-MB-435 cell adhesion and invasion by inhibiting matrix metalloproteinase-9
10.3892/mmr.2015.3541 · 2015 · External reference
Ophiopogonin D′, a Natural Product From Radix Ophiopogonis, Induces in Vitro and in Vivo RIPK1-Dependent and Caspase-Independent Apoptotic Death in Androgen-Independent Human Prostate Cancer Cells
10.3389/fphar.2018.00432 · 2018 · External reference
Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells
10.1016/j.phymed.2018.01.002 · 2018 · External reference
An immunopotentiator, ophiopogonin D, encapsulated in a nanoemulsion as a robust adjuvant to improve vaccine efficacy
10.1016/j.actbio.2018.07.034 · 2018 · External reference
Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
10.3390/cancers10110427 · 2018 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Accelerating AutoDock Vina with GPUs
10.3390/molecules27093041 · 2022 · External reference
State-specific protein–ligand complex structure prediction with a multiscale deep generative model
10.1038/s42256-024-00792-z · 2024 · External reference
Exosome-mediated crosstalk between tumor cells and innate immune cells: implications for cancer progression and therapeutic strategies
10.1007/s00432-023-04833-9 · 2023 · External reference
The Emerging Mechanisms and Therapeutic Potentials of Dendritic Cells in NSCLC
10.2147/jir.s506644 · 2025 · External reference
Artesunate attenuates isoprenaline induced cardiac hypertrophy in rats via SIRT1 inhibiting NF-κB activation
10.1016/j.ejphar.2024.176709 · 2024 · External reference
Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway
10.1080/13880209.2023.2292256 · 2024 · External reference
Base-Resolution Analysis of Cisplatin-DNA Adducts at the Genome Scale
10.1002/anie.201607380 · 2016 · External reference
Dynamic monitoring of PD-L1 and Ki67 in circulating tumor cells of metastatic non-small cell lung cancer patients treated with pembrolizumab
10.1002/1878-0261.13317 · 2023 · External reference
Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
10.1038/s41419-022-05454-9 · 2022 · External reference
Exosomes derived from human umbilical cord Wharton's jelly mesenchymal stem cells ameliorate experimental lymphedema
10.1002/ctm2.384 · 2021 · External reference
Immunoradiotherapy for NSCLC: mechanisms, clinical outcomes, and future directions
10.1007/s12094-023-03337-9 · 2024 · External reference
Natural bioactives in cancer treatment and prevention
10.1155/2015/182835 · 2015 · External reference
Bioactive natural products in cancer prevention and therapy: Progress and promise
10.1016/j.semcancer.2016.08.006 · 2016 · External reference
Comparison of Ophiopogon japonicus and Liriope spicata var. prolifera from Different Origins Based on Multi-Component Quantification and Anticancer Activity
10.3390/molecules28031045 · 2023 · External reference
Ophiopogonin D suppresses TGF-β1-mediated metastatic behavior of MDA-MB-231 breast carcinoma cells via regulating ITGB1/FAK/Src/AKT/β-catenin/MMP-9 signaling axis
10.1016/j.tiv.2020.104973 · 2020 · External reference
Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells
10.1016/s2095-4964(16)60238-8 · 2016 · External reference
Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation
10.1007/s10787-024-01531-x · 2024 · External reference
Strategy and application of manipulating DCs chemotaxis in disease treatment and vaccine design
10.1016/j.biopha.2023.114457 · 2023 · External reference
Logical modelling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions
10.1098/rsfs.2020.0061 · 2021 · External reference
Echinococcus granulosus Protoscoleces-Derived Exosome-like Vesicles and Egr-miR-277a-3p Promote Dendritic Cell Maturation and Differentiation
10.3390/cells11203220 · 2022 · External reference
Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-κB pathway
10.1590/1414-431x2021e11062 · 2021 · External reference
Discovery of novel adjuvants: Identification of saponins from Hylomecon japonica (Thunb.) Prantl & Kündig and insights into their in vitro and in vivo activities
10.1016/j.bioorg.2025.108501 · 2025 · External reference
SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
10.7554/elife.67452 · 2021 · External reference
LncRNA MALAT1 Enhances ox-LDL-Induced Autophagy through the SIRT1/MAPK/NF-κB Pathway in Macrophages
10.2174/1570161118666200317153124 · 2020 · External reference
Protective roles of SIRT1 in atherosclerosis
10.4161/cc.10.4.14863 · 2011 · External reference
MiR-217 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation by down-regulation of SIRT1
10.1016/j.bbamcr.2012.02.014 · 2012 · External reference
The effect of tumor-derived exosomes on immune regulation and cancer immunotherapy
10.2217/fon-2017-0343 · 2017 · External reference
Forging New Therapeutic Targets: Efforts of Tumor Derived Exosomes to Prepare the Pre-Metastatic Niche for Cancer Cell Dissemination and Dormancy
10.3390/biomedicines11061614 · 2023 · External reference
Diagnostic and therapeutic potential of exosomal circRNAs in cancer: decoding the circular code toward precision medicine
10.1186/s12935-025-04053-w · 2025 · External reference
The long noncoding RNA MALAT1 suppresses miR-211 to confer protection from ultraviolet-mediated DNA damage in vitiligo epidermis by upregulating sirtuin 1
10.1111/bjd.19666 · 2021 · External reference
LncRNA MALAT1 improves cerebral ischemia-reperfusion injury and cognitive dysfunction by regulating miR-142-3p/SIRT1 axis
10.1080/00207454.2021.1972999 · 2023 · External reference
BML-111 alleviates acute lung injury through regulating the expression of lncRNA MALAT1
10.1016/j.abb.2018.04.016 · 2018 · External reference
Long Noncoding RNAs MALAT1 and HOTTIP Act as Serum Biomarkers for Hepatocellular Carcinoma
10.1177/10732748241284821 · 2024 · External reference
Long noncoding RNAs: role and contribution in pancreatic cancer
10.1080/21541264.2021.1922071 · 2021 · External reference
Predicting small molecule-RNA interactions without RNA tertiary structures
10.1038/s41587-025-02942-z · 2026 · External reference
