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References from Probiotics Attenuate AlCl₃-Induced Alzheimer’s Disease via Gut–Brain Axis Modulation and Suppression of NF-κB/NLRP3 Neuroinflammation. Local targets link to admitted publications; unresolved targets remain external evidence.
10.12779/dnd.2026.25.1.1
10.12779/dnd.2026.25.1.1 · External reference
Gut microbes and the brain: paradigm shift in neuroscience
10.1523/jneurosci.3299-14.2014 · 2014 · External reference
10.1021/acschemneuro.5c00063
10.1021/acschemneuro.5c00063 · External reference
The role of LRP1 in Aβ efflux transport across the blood-brain barrier and cognitive dysfunction in diabetes mellitus
10.1016/j.neuint.2022.105417 · 2022 · External reference
LRP1 at the crossroads of Aβ clearance and therapeutic targeting in Alzheimer’s disease
2026 · External reference
Gut microbiota: a promising new target in immune tolerance
10.3389/fimmu.2025.1607388 · 2025 · External reference
Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review
10.1016/j.biopha.2023.114985 · 2023 · External reference
Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
10.1016/j.neurobiolaging.2016.08.019 · 2017 · External reference
Human supplementation with Pediococcus acidilactici GR-1 decreases heavy metals levels through modifying the gut microbiota and metabolome
10.1038/s41522-022-00326-8 · 2022 · External reference
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading
10.1084/jem.20172158 · 2018 · External reference
Signaling to NF-κB by Toll-like receptors
10.1016/j.molmed.2007.09.002 · 2007 · External reference
NF-κB, IκB, and IKK: Integral Components of Immune System Signaling
10.1007/978-981-13-9367-9_10 · 2019 · External reference
10.1136/gpsych-2023-101374
10.1136/gpsych-2023-101374 · External reference
GABA-modulating bacteria of the human gut microbiota
10.1038/s41564-018-0307-3 · 2019 · External reference
A synbiotic multiparticulate microcapsule for enhancing inulin intestinal release and Bifidobacterium gastro-intestinal survivability
10.1016/j.carbpol.2018.03.068 · 2018 · External reference
Ameliorative effect of probiotic-fermented milk and costus extract in Alzheimer’s disease model induced by D-galactose and aluminum chloride
2022 · External reference
Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
10.1016/j.fct.2012.11.016 · 2013 · External reference
Prolactin is a peripheral marker of manganese neurotoxicity
10.1016/j.brainres.2011.01.047 · 2011 · External reference
A hitchhiker's guide to behavioral analysis in laboratory rodents
10.1111/j.1601-183x.2006.00228.x · 2006 · External reference
Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice
10.1002/hipo.22756 · 2017 · External reference
Exercise improves memory acquisition and retrieval in the Y-maze task: relationship with hippocampal neurogenesis
10.1037/0735-7044.121.2.324 · 2007 · External reference
Quercetin stimulates the non-amyloidogenic pathway via activation of ADAM10 and ADAM17 gene expression in aluminum chloride-induced Alzheimer's disease rat model
10.1016/j.lfs.2021.119964 · 2021 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
2018 · External reference
Improved metagenomic analysis with Kraken 2
10.1186/s13059-019-1891-0 · 2019 · External reference
phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data
10.1371/journal.pone.0061217 · 2013 · External reference
Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail
10.1038/s41598-024-84780-8 · 2025 · External reference
Microbiota-derived IPA alleviates intestinal mucosal inflammation through upregulating Th1/Th17 cell apoptosis in inflammatory bowel disease
10.1080/19490976.2025.2467235 · 2025 · External reference
The preventive effects of probiotic Akkermansia muciniphila on D-galactose/AlCl3 mediated Alzheimer's disease-like rats
10.1016/j.exger.2022.111959 · 2022 · External reference
10.1080/19490976.2020.1802866
10.1080/19490976.2020.1802866 · External reference
Gut microbiota-driven metabolic alterations reveal gut-brain communication in Alzheimer's disease model mice
10.1080/19490976.2024.2302310 · 2024 · External reference
Unveiling the Intricate Link Between Anaerobe Niche and Alzheimer Disease Pathogenesis
10.1093/infdis/jiae312 · 2024 · External reference
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease
10.1186/s12974-022-02599-4 · 2022 · External reference
Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice
10.4049/jimmunol.1100500 · 2011 · External reference
High-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation
10.1074/jbc.ra118.002428 · 2018 · External reference
Serum amyloid A-mediated neuro-inflammation induces hippocampal neuron apoptosis and postoperative cognitive dysfunction in mice
2025 · External reference
Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia
10.1523/jneurosci.0801-19.2019 · 2019 · External reference
Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer’s disease
10.1016/j.jneuroim.2018.11.010 · 2019 · External reference
Involvement of astrocytes in Alzheimer’s disease from a neuroinflammatory and oxidative stress perspective
10.3389/fnmol.2017.00427 · 2017 · External reference
Postbiotics alleviate cognitive impairment and neuroinflammation via gut-brain axis and TLR4/MyD88/NLRP3 pathway
10.1016/j.foodres.2025.117708 · 2025 · External reference
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
10.1038/nature08530 · 2009 · External reference
Effect of Clostridium butyricum against Microglia-Mediated Neuroinflammation in Alzheimer's Disease via Regulating Gut Microbiota and Metabolites Butyrate
10.1002/mnfr.201900636 · 2020 · External reference
10.3390/healthcare13010074
10.3390/healthcare13010074 · External reference
Microbial-generated amyloids and Alzheimer's disease (AD)
2015 · External reference
Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice
10.1002/glia.24007 · 2021 · External reference
RAGE mediates Aβ accumulation in a mouse model of Alzheimer’s disease via modulation of β- and γ-secretase activity
10.1093/hmg/ddy017 · 2018 · External reference
10.1139/apnm-2017-0648
10.1139/apnm-2017-0648 · External reference
Lactobacilli and bifidobacteria ameliorate memory and learning deficits and oxidative stress in β-amyloid (1–42) injected rats
10.1139/apnm-2017-0648 · 2018 · External reference
Probiotic Bifidobacterium breve prevents memory impairment through the reduction of both amyloid-β production and microglia activation in APP knock-in mouse
10.3233/jad-215025 · 2022 · External reference
Probiotics administration alleviates cognitive impairment and circadian rhythm disturbance induced by sleep deprivation
10.26599/fshw.2022.9250162 · 2024 · External reference
Akkermansia muciniphila-derived extracellular vesicles alleviate depressive-like behaviors via hippocampal protection and gut metabolic modulation
10.1016/j.fbio.2026.108904 · 2026 · External reference
