References

The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria

10.1007/s11064-010-0331-z · 2011 · External reference

Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy

10.1529/biophysj.104.046722 · 2005 · External reference

Covid-19 pandemic impact on mental health of vulnerable populations

2020 · External reference

Brain gene expression pattern of subjects with completed suicide and comorbid substance use disorder

2019 · External reference

Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway

10.1093/toxsci/kft254 · 2014 · External reference

Activation of spinal PGC-1α regulates microglial polarization through a feedback loop between ROS-mediated mitochondrial dysfunction and the NLRP3 inflammasome in neuropathic pain

10.1016/j.brainresbull.2025.111365 · 2025 · External reference

In vitro effects of antidepressants and mood-stabilizing drugs on cell energy metabolism

10.1007/s00210-019-01791-3 · 2020 · External reference

Antidepressant use and risk of adverse outcomes in older people: population based cohort study

10.1136/bmj.d4551 · 2011 · External reference

Antidepressant use and risk of suicide and attempted suicide or self harm in people aged 20 to 64: cohort study using a primary care database

2015 · External reference

The complex interaction of mitochondrial genetics and mitochondrial pathways in psychiatric disease

2018 · External reference

Alexithymia, suicide ideation, affective temperaments and homocysteine levels in drug naïve patients with post-traumatic stress disorder: an exploratory study in the everyday ‘real world’ clinical practice

10.1080/13651501.2019.1699575 · 2020 · External reference

Transcriptome profiling of the dorsomedial prefrontal cortex in suicide victims

10.3390/ijms23137067 · 2022 · External reference

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRα and γ

10.1016/j.cmet.2007.03.007 · 2007 · External reference

Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks

10.1016/j.mito.2011.03.121 · 2011 · External reference

Mitochondrial transcription factor a regulates mtDNA copy number in mammals

10.1093/hmg/ddh109 · 2004 · External reference

Antidepressants are cytotoxic to rat primary blood brain barrier endothelial cells at high therapeutic concentrations

10.1016/j.tiv.2017.07.011 · 2017 · External reference

Effect of neuropsychiatric medications on mitochondrial function: for better or for worse

10.1016/j.neubiorev.2021.05.001 · 2021 · External reference

Approaches and findings from gene expression profiling studies of suicide

2012 · External reference

Genetic and neurobiological approaches to understanding suicidal behaviors

2014 · External reference

31Phosphorus magnetic resonance spectroscopy study of tissue specific changes in high energy phosphates before and after sertraline treatment of geriatric depression

10.1002/gps.2230 · 2009 · External reference

Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy

10.1038/s41531-022-00369-w · 2022 · External reference

Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: relevance for transcriptional changes in Huntington disease

10.1016/j.nbd.2025.106818 · 2025 · External reference

Creation of a gene expression portrait of depression and its application for identifying potential treatments

10.1038/s41598-021-83348-0 · 2021 · External reference

Pilot randomized clinical trial of an SSRI vs bupropion: effects on suicidal behavior, ideation, and mood in major depression

10.1038/npp.2011.247 · 2012 · External reference

Emergence of antidepressant induced suicidality

10.1185/135525700543163 · 2000 · External reference

Antidepressants and suicide: risk-benefit conundrums

10.1139/jpn.0340 · 2003 · External reference

Antidepressant use and suicide rates in adults aged 75 and above: a Swedish nationwide cohort study

10.3389/fpubh.2021.611559 · 2021 · External reference

Neuroinflammation, stress-related suicidal ideation, and negative mood in depression

10.1001/jamapsychiatry.2024.3543 · 2025 · External reference

Transcriptional control of mitochondrial biogenesis and function

10.1146/annurev.physiol.010908.163119 · 2009 · External reference

Elevated translocator protein in anterior cingulate in major depression and a role for inflammation in suicidal thinking: a positron emission tomography study

10.1016/j.biopsych.2017.08.005 · 2018 · External reference

Inhibitory effects of SSRIs on IFN-γ induced microglial activation through the regulation of intracellular calcium

10.1016/j.pnpbp.2010.07.015 · 2010 · External reference

Activities of respiratory chain complexes and citrate synthase influenced by pharmacologically different antidepressants and mood stabilizers

2010 · External reference

Blood disorders and suicide in patients taking mianserin or amitriptyline

10.1016/s0140-6736(88)90016-5 · 1988 · External reference

Linkage and association of the glutamate receptor 6 gene with autism

10.1038/sj.mp.4000979 · 2002 · External reference

Requirement of AMPK activation for neuronal metabolic-enhancing effects of antidepressant paroxetine

10.1097/wnr.0000000000000365 · 2015 · External reference

Antidepressants and the risk of suicidal behaviors

10.1001/jama.292.3.338 · 2004 · External reference

Microglia: housekeeper of the central nervous system

10.1007/s10571-017-0504-2 · 2018 · External reference

Antidepressants and suicidality: a re-analysis of the re-analysis

10.1016/j.jad.2020.01.107 · 2020 · External reference

Depression, mitochondrial bioenergetics, and electroconvulsive therapy: a new approach towards personalized medicine in psychiatric treatment - a short review and current perspective

10.1038/s41398-020-00901-7 · 2020 · External reference

Connecting dots between mitochondrial dysfunction and depression

10.3390/biom13040695 · 2023 · External reference

Suicide candidate genes associated with bipolar disorder and schizophrenia: an exploratory gene expression profiling analysis of post-mortem prefrontal cortex

10.1186/1471-2164-8-413 · 2007 · External reference

ERRγ ligand regulates adult neurogenesis and depression-like behavior in a LRRK2-G2019S-associated young female mouse model of Parkinson’s disease

10.1007/s13311-022-01244-5 · 2022 · External reference

Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression

10.1038/sj.mp.4002110 · 2009 · External reference

A mitochondrial bioenergetic basis of depression

10.1007/s10863-014-9584-6 · 2015 · External reference

Major depressive disorder is associated with impaired mitochondrial function in skin fibroblasts

10.3390/cells9040884 · 2020 · External reference

Genetic markers of suicidal ideation emerging during citalopram treatment of major depression

10.1176/appi.ajp.2007.06122018 · 2007 · External reference

Prescription medications for the treatment of insomnia and risk of suicide attempt: a comparative safety study

10.1007/s11606-019-05030-6 · 2019 · External reference

Mitochondrial dysfunction induced by sertraline, an antidepressant agent

10.1093/toxsci/kfs100 · 2012 · External reference

The association between alexithymia as assessed by the 20-item Toronto alexithymia scale and depression: a meta-analysis

10.1016/j.psychres.2015.02.006 · 2015 · External reference

Mitochondrial dysfunction in microglia: a novel perspective for pathogenesis of Alzheimer’s disease

10.1186/s12974-022-02613-9 · 2022 · External reference

Effects of selective serotonin reuptake inhibitors (SSRIs) on suicide: a network meta-analysis of double-blind randomized trials

10.1016/j.psychres.2024.115917 · 2024 · External reference

The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity

10.1213/01.ane.0000216018.62549.bb · 2006 · External reference

Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

10.1186/1742-2094-11-47 · 2014 · External reference

Modulation of microglial activation by antidepressants

10.1177/02698811211069110 · 2022 · External reference

Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation

10.1176/appi.ajp.2008.08020274 · 2008 · External reference

Genome-wide association study of antidepressant treatment-emergent suicidal ideation

10.1038/npp.2011.257 · 2012 · External reference

Differential effects on suicidal ideation of mianserin, maprotiline and amitriptyline

1978 · External reference

Reduction of suicidal thoughts with paroxetine in comparison with reference antidepressants and placebo

10.1016/0924-977x(94)00131-t · 1995 · External reference

Cytotoxic effects of amitriptyline in human fibroblasts

10.1016/j.tox.2007.09.021 · 2008 · External reference

Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ

10.1016/j.cmet.2011.01.019 · 2011 · External reference

Optimization of receptor-G protein coupling by bilayer lipid composition II: formation of metarhodopsin II-transducin complex

10.1074/jbc.m105778200 · 2001 · External reference

Antidepressants and suicide mortality

10.1016/s0165-0327(98)00114-1 · 1998 · External reference

Antineuroinflammatory and neuroprotective effects of Gyejibokryeong-Hwan in lipopolysaccharide-stimulated BV2 microglia

10.1155/2019/7585896 · 2019 · External reference

The effect of tricyclic antidepressants on cutaneous melanoma cell lines and primary cell cultures

10.1097/cad.0b013e32834b1894 · 2012 · External reference

Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism

10.1016/j.cmet.2015.03.004 · 2015 · External reference

Suicidal ideation during antidepressant treatment: do genetic predictors exist?

10.2165/11589420-000000000-00000 · 2011 · External reference

Antidepressants and COVID-19: increased use, occurrence in water and effects and consequences on aquatic environment. A review

10.1016/j.scitotenv.2024.175993 · 2024 · External reference

Genetics and brain transcriptomics of completed suicide

10.1176/appi.ajp.2021.21030299 · 2022 · External reference

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

10.1038/nature03354 · 2005 · External reference

Suicidality and suicide attempt in a young female on long-term sertraline treatment

10.4103/0253-7176.108230 · 2012 · External reference

ERRα and ERRγ coordinate expression of genes associated with Alzheimer’s disease, inhibiting DKK1 to suppress tau phosphorylation

10.1073/pnas.2406854121 · 2024 · External reference

Activity of mitochondrial respiratory chain is increased by chronic administration of antidepressants

10.1111/j.1601-5215.2011.00548.x · 2011 · External reference

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

10.1152/physrev.00025.2007 · 2008 · External reference

Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years’ data

10.1001/archgenpsychiatry.2010.39 · 2010 · External reference

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

10.1038/mp.2008.20 · 2008 · External reference

Antidepressants

2023 · External reference

Mental health: a world of depression

10.1038/515180a · 2014 · External reference

Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome

10.1159/000326692 · 2011 · External reference

Genetic origins of suicidality? A synopsis of genes in suicidal behaviours, with regard to evidence diversity, disorder specificity and neurodevelopmental brain transcriptomics

10.1016/j.euroneuro.2020.06.002 · 2020 · External reference

Molecular consequences of depression treatment: a potential in vitro mechanism for antidepressants-induced reprotoxic side effects

10.3390/ijms222111855 · 2021 · External reference

Distribution of HLA-DR-positive microglia in schizophrenia reflects impaired cerebral lateralization

10.1007/s00401-006-0090-8 · 2006 · External reference

Editorial: what is depression?

10.1111/jcpp.12844 · 2017 · External reference

The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism

10.1371/journal.pone.0067810 · 2013 · External reference

Emergence of intense suicidal preoccupation during fluoxetine treatment

10.1176/ajp.147.2.207 · 1990 · External reference

Antidepressant drugs and the emergence of suicidal tendencies

10.2165/00002018-199308030-00002 · 1993 · External reference

Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes

10.18632/oncotarget.23302 · 2017 · External reference

Pre-treatment with amitriptyline causes epigenetic up-regulation of neuroprotection-associated genes and has anti-apoptotic effects in mouse neuronal cells

10.1016/j.ntt.2017.05.002 · 2017 · External reference

A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia

10.1016/j.bbi.2011.12.011 · 2012 · External reference

Effect of trazodone on oxidative metabolism of rat brain in vitro

1985 · External reference

Reduction by paroxetine of suicidal behavior in patients with repeated suicide attempts but not major depression

10.1176/ajp.155.4.543 · 1998 · External reference

Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells

10.18632/genesandcancer.114 · 2016 · External reference

Predictors of change in suicidal ideation across treatment phases of major depressive disorder: analysis of the STAR*D data

10.1038/s41386-020-00953-9 · 2021 · External reference

Unresolved reference

External reference

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

10.1016/s0092-8674(00)80611-x · 1999 · External reference

The central role of microglia in major depressive disorder and its potential as a therapeutic target

10.3389/fnbeh.2025.1598178 · 2025 · External reference

Glial markers of suicidal behavior in the human brain-a systematic review of postmortem studies

10.3390/ijms25115750 · 2024 · External reference

The effects of psychological stress on depression

10.2174/1570159x1304150831150507 · 2015 · External reference

Resveratrol regulates microglia M1/M2 polarization via PGC-1α in conditions of neuroinflammatory injury

10.1016/j.bbi.2017.03.003 · 2017 · External reference

Platycodigenin as potential drug candidate for Alzheimer’s disease via modulating microglial polarization and neurite regeneration

10.3390/molecules24183207 · 2019 · External reference

The critical role of P2XR/PGC-1α signalling pathway in hypoxia-mediated pyroptosis and M1/M2 phenotypic differentiation of mouse microglia

10.1111/ejn.16363 · 2024 · External reference

Genetic analysis of the GRIK2 modifier effect in Huntington’s disease

10.1186/1471-2202-7-62 · 2006 · External reference

Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease

10.1073/pnas.1804965115 · 2018 · External reference