Research graph
References from 40-Hz chirp auditory stimulation alleviates chronic restraint stress-induced depression-like behaviors and restores disrupted gamma oscillations. Local targets link to admitted publications; unresolved targets remain external evidence.
Gamma entrainment: impact on neurocircuits, glia, and therapeutic opportunities
10.1016/j.tins.2019.11.001 · 2019 · External reference
Gamma entrainment binds higher-order brain regions and offers neuroprotection
10.1016/j.neuron.2019.04.011 · 2019 · External reference
Treatment-resistant depression: therapeutic trends, challenges, and future directions
10.2147/ppa.s29716 · 2012 · External reference
D-limonene reduces depression-like behaviour and enhances learning and memory through an anti-neuroinflammatory mechanism in male rats subjected to chronic restraint stress
10.1111/ejn.16455 · 2024 · External reference
Rhythmic modulation of visual perception by continuous rhythmic auditory stimulation
10.1523/jneurosci.2980-20.2021 · 2020 · External reference
Relationship of hippocampal Theta and gamma oscillations to potentiation of synaptic transmission
10.3389/neuro.01.010.2008 · 2008 · External reference
Therapeutic potential of gamma entrainment using sensory stimulation for cognitive symptoms associated with schizophrenia
10.1016/j.neubiorev.2024.105681 · 2024 · External reference
Mechanisms of gamma oscillations
10.1146/annurev-neuro-062111-150444 · 2012 · External reference
The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes
10.1038/nrn3241 · 2012 · External reference
Ketamine alters oscillatory coupling in the hippocampus
10.1038/srep02348 · 2013 · External reference
A functional magnetic resonance imaging study of cortical asymmetry in bipolar disorder
10.1111/j.1399-5618.2004.00116.x · 2004 · External reference
LS CE-chirp® vs. click in the neuroaudiological diagnosis by ABR
10.1016/j.bjorl.2016.04.018 · 2016 · External reference
A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
10.1038/mp.2011.31 · 2012 · External reference
Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex
10.1016/j.pnpbp.2012.05.018 · 2012 · External reference
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis
10.1016/s0140-6736(17)32802-7 · 2018 · External reference
Short-term effects of rhythmic sensory stimulation in Alzheimer's disease: an exploratory pilot study
10.3233/jad-160081 · 2016 · External reference
Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms
10.1038/nrn2345 · 2008 · External reference
Auditory steady-state responses to chirp stimuli based on cochlear traveling wave delay
10.1121/1.2783985 · 2007 · External reference
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression
10.1038/s41386-020-0663-6 · 2020 · External reference
Altered structure of dynamic electroencephalogram oscillatory pattern in major depression
10.1016/j.biopsych.2014.12.011 · 2015 · External reference
Gamma oscillations as a biomarker for major depression: an emerging topic
10.1038/s41398-018-0239-y · 2018 · External reference
A 40-Hz auditory potential recorded from the human scalp
10.1073/pnas.78.4.2643 · 1981 · External reference
Electrophysiological biomarkers of antidepressant response to ketamine in treatment-resistant depression: gamma power and long-term potentiation
10.1016/j.pbb.2020.172856 · 2020 · External reference
Stimulus-evoked phase-locked activity along the human auditory pathway strongly varies across individuals
10.1038/s41598-020-80229-w · 2021 · External reference
40Hz auditory steady-state response in schizophrenia: sensitivity to stimulation type (clicks versus flutter amplitude-modulated tones)
10.1016/j.neulet.2017.10.025 · 2018 · External reference
40-Hz temporally interfering electrical stimulation over the temporal lobe induced antidepressant-like effects in chronic unpredictable mild stress rats
10.1109/tnsre.2025.3565099 · 2025 · External reference
Gamma auditory steady-state response as a promising electrophysiological biomarker for depression: an in vivo study with chronic unpredictable mild stress (CUS)-induced rats
10.1093/cercor/bhad076 · 2023 · External reference
Unresolved reference
2023 · External reference
A pilot study investigating the effect of music-based intervention on depression and anhedonia
2019 · External reference
Induced gamma-band activity and human brain function
10.1177/1073858403259137 · 2003 · External reference
Unresolved reference
2019 · External reference
A thalamic-primary auditory cortex circuit mediates resilience to stress
10.1016/j.cell.2023.02.036 · 2023 · External reference
Enhanced auditory steady-state response using an optimized chirp stimulus-evoked paradigm
2019 · External reference
Neurophysiological markers of depression detection and severity prediction in first-episode major depressive disorder
2023 · External reference
Neurophysiological signatures of major depressive disorder and Frontocentral gamma auditory response deficits
10.1155/da/7390951 · 2025 · External reference
An update on the use of gamma (multi)sensory stimulation for Alzheimer's disease treatment
10.3389/fnagi.2022.1095081 · 2022 · External reference
Multi-sensory gamma stimulation ameliorates Alzheimer's-associated pathology and improves cognition
10.1016/j.cell.2019.02.014 · 2019 · External reference
Depression in the elderly
10.64719/pb.6864 · 2015 · External reference
Investigating the effects of auditory and vibrotactile rhythmic sensory stimulation on depression: an EEG pilot study
2022 · External reference
Resting-state EEG gamma power and theta–gamma coupling enhancement following high-frequency left dorsolateral prefrontal rTMS in patients with depression
10.1016/j.clinph.2016.12.023 · 2017 · External reference
Enhanced theta-gamma coupling associated with hippocampal volume increase following high-frequency left prefrontal repetitive transcranial magnetic stimulation in patients with major depression
10.1016/j.ijpsycho.2018.07.004 · 2018 · External reference
Decreased BOLD signals elicited by 40-Hz auditory stimulation of the right primary auditory cortex in bipolar disorder: an fMRI study
10.3389/fpsyt.2022.833896 · 2022 · External reference
Cortical oscillations scan using chirp-evoked potentials in 6-hydroxydopamine rat model of Parkinson's disease
10.1016/j.brainres.2009.11.031 · 2010 · External reference
The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder. A critical review
10.1016/s0163-7258(00)00063-2 · 2000 · External reference
Right hemispheric laterality of human 40 Hz auditory steady-state responses
10.1093/cercor/bhi078 · 2005 · External reference
Protective effects of carnosol against oxidative stress induced brain damage by chronic stress in rats
10.1186/s12906-017-1753-9 · 2017 · External reference
40Hz auditory steady-state response is a pharmacodynamic biomarker for cortical NMDA receptors
10.1038/npp.2016.17 · 2016 · External reference
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
10.1038/nature07991 · 2009 · External reference
Application of frequency modulated chirp stimuli for rapid and sensitive ABR measurements in the rat
10.1016/j.heares.2008.09.001 · 2008 · External reference
Modulation of gamma oscillations as a possible therapeutic tool for neuropsychiatric diseases: a review and perspective
10.1016/j.ijpsycho.2020.03.003 · 2020 · External reference
Deep brain stimulation modulates gamma oscillations and theta–gamma coupling in treatment resistant depression
10.1016/j.brs.2015.06.010 · 2015 · External reference
Gamma-band auditory steady-state response as a neurophysiological marker for excitation and inhibition balance: a review for understanding schizophrenia and other neuropsychiatric disorders
10.1177/1550059419868872 · 2019 · External reference
Measuring phase-amplitude coupling between neuronal oscillations of different frequencies
10.1152/jn.00106.2010 · 2010 · External reference
Altered fronto-central theta-gamma coupling in major depressive disorder during auditory steady-state responses
10.1016/j.clinph.2022.11.013 · 2022 · External reference
Fronto-parietal and temporal brain dysfunction in depression: a fMRI investigation of auditory mismatch processing
10.1002/hbm.24623 · 2019 · External reference
